8OM1
 
 | | Mitochondrial complex I from Mus musculus in the active state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J. | | Deposit date: | 2023-03-31 | | Release date: | 2023-08-09 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (2.39 Å) | | Cite: | Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
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8OH9
 | | Cryo-EM structure of the electron bifurcating transhydrogenase StnABC complex from Sporomusa Ovata (state 1) | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, Formate dehydrogenase-O, ... | | Authors: | Kumar, A, Kremp, F, Mueller, V, Schuller, J.M. | | Deposit date: | 2023-03-20 | | Release date: | 2023-09-13 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular architecture and electron transfer pathway of the Stn family transhydrogenase.
Nat Commun, 14, 2023
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8OH5
 | | Cryo-EM structure of the electron bifurcating transhydrogenase StnABC complex from Sporomusa Ovata (state 2) | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Kumar, A, Kremp, F, Mueller, V, Schuller, J.M. | | Deposit date: | 2023-03-20 | | Release date: | 2023-09-13 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Molecular architecture and electron transfer pathway of the Stn family transhydrogenase.
Nat Commun, 14, 2023
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3IAM
 | | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, reduced, 2 mol/ASU, with bound NADH | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Sazanov, L.A, Berrisford, J.M. | | Deposit date: | 2009-07-14 | | Release date: | 2009-09-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for the mechanism of respiratory complex I
J.Biol.Chem., 284, 2009
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3I9V
 | | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, oxidized, 2 mol/ASU | | Descriptor: | CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Sazanov, L.A, Berrisford, J.M. | | Deposit date: | 2009-07-13 | | Release date: | 2009-09-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for the mechanism of respiratory complex I
J.Biol.Chem., 284, 2009
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3IAS
 | | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, oxidized, 4 mol/ASU, re-refined to 3.15 angstrom resolution | | Descriptor: | CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Sazanov, L.A, Berrisford, J.M. | | Deposit date: | 2009-07-14 | | Release date: | 2009-09-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural basis for the mechanism of respiratory complex I
J.Biol.Chem., 284, 2009
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6Q8X
 | | Respiratory complex I from Thermus thermophilus with bound Pyridaben. | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | Authors: | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | | Deposit date: | 2018-12-16 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.508 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6Q8W
 | | Respiratory complex I from Thermus thermophilus with bound Aureothin. | | Descriptor: | Aureothin, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | | Deposit date: | 2018-12-16 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6RFQ
 | | Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | | Authors: | Parey, K, Vonck, J. | | Deposit date: | 2019-04-16 | | Release date: | 2019-12-11 | | Last modified: | 2021-06-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease.
Sci Adv, 5, 2019
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2FUG
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6RFR
 | | Cryo-EM structure of respiratory complex I from Yarrowia lipolytica at 3.2 A resolution | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | | Authors: | Parey, K, Vonck, J. | | Deposit date: | 2019-04-16 | | Release date: | 2019-12-11 | | Last modified: | 2021-06-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease.
Sci Adv, 5, 2019
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6Q8O
 | | Respiratory complex I from Thermus thermophilus with bound Piericidin A | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | Authors: | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | | Deposit date: | 2018-12-15 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.605 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6RFS
 | | Cryo-EM structure of a respiratory complex I mutant lacking NDUFS4 | | Descriptor: | Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Parey, K, Vonck, J. | | Deposit date: | 2019-04-16 | | Release date: | 2019-12-11 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (4.04 Å) | | Cite: | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease.
Sci Adv, 5, 2019
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6YJ4
 | | Structure of Yarrowia lipolytica complex I at 2.7 A | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | | Authors: | Hirst, J, Grba, D. | | Deposit date: | 2020-04-02 | | Release date: | 2020-08-12 | | Last modified: | 2021-03-17 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation.
Nat.Struct.Mol.Biol., 27, 2020
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6ZJN
 | | Respiratory complex I from Thermus thermophilus, NADH dataset, minor state | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, NADH-quinone oxidoreductase subunit 1, ... | | Authors: | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | | Deposit date: | 2020-06-29 | | Release date: | 2020-09-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6ZJL
 | | Respiratory complex I from Thermus thermophilus, NAD+ dataset, major state | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | Authors: | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | | Deposit date: | 2020-06-29 | | Release date: | 2020-09-02 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6ZIY
 | | Respiratory complex I from Thermus thermophilus, NADH dataset, major state | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | | Deposit date: | 2020-06-26 | | Release date: | 2020-09-02 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6ZTQ
 | | Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. | | Deposit date: | 2020-07-20 | | Release date: | 2020-10-21 | | Last modified: | 2020-10-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
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7A24
 | | Assembly intermediate of the plant mitochondrial complex I | | Descriptor: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | | Authors: | Soufari, H, Waltz, F, Hashem, Y. | | Deposit date: | 2020-08-16 | | Release date: | 2020-10-28 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
Nat Commun, 11, 2020
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6ZJY
 | | Respiratory complex I from Thermus thermophilus, NAD+ dataset, minor state | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, NADH-quinone oxidoreductase subunit 1, ... | | Authors: | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | | Deposit date: | 2020-06-29 | | Release date: | 2020-09-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6ZR2
 | | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. | | Deposit date: | 2020-07-10 | | Release date: | 2020-10-21 | | Last modified: | 2020-10-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
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7A23
 | | Plant mitochondrial respiratory complex I | | Descriptor: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | | Authors: | Soufari, H, Waltz, F, Hashem, Y. | | Deposit date: | 2020-08-15 | | Release date: | 2020-10-28 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
Nat Commun, 11, 2020
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7AK6
 | | Cryo-EM structure of ND6-P25L mutant respiratory complex I from Mus musculus at 3.8 A | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | | Deposit date: | 2020-09-29 | | Release date: | 2021-02-03 | | Last modified: | 2021-02-10 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | Structural basis for a complex I mutation that blocks pathological ROS production.
Nat Commun, 12, 2021
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1G8J
 | | CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, ARSENITE OXIDASE, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Ellis, P.J, Conrads, T, Hille, R, Kuhn, P. | | Deposit date: | 2000-11-17 | | Release date: | 2000-12-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.
Structure, 9, 2001
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1G8K
 | | CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, ARSENITE OXIDASE, ... | | Authors: | Ellis, P.J, Conrads, T, Hille, R, Kuhn, P. | | Deposit date: | 2000-11-17 | | Release date: | 2000-12-13 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.
Structure, 9, 2001
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