5WJW
 
 | | Cryo-EM structure of B. subtilis flagellar filaments H84R | | Descriptor: | Flagellin | | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | | Deposit date: | 2017-07-24 | | Release date: | 2017-10-25 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | A structural model of flagellar filament switching across multiple bacterial species.
Nat Commun, 8, 2017
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4X2D
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3HUO
 | | X-ray crystallographic structure of CTX-M-9 S70G in complex with benzylpenicillin | | Descriptor: | (2R,4S)-2-{(R)-carboxy[(phenylacetyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CTX-M-9 extended-spectrum beta-lactamase, PENICILLIN G | | Authors: | Delmas, J, Leyssene, D, Dubois, D, Robin, F, Bonnet, R. | | Deposit date: | 2009-06-15 | | Release date: | 2010-05-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Dynamic view of the early and late steps of the catalytic mechanism mediated by the emerging enzymes CTX-M.
To be Published
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5WJV
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3HVI
 | | Rat catechol O-methyltransferase in complex with a catechol-type, N6-ethyladenine-containing bisubstrate inhibitor | | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ... | | Authors: | Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. | | Deposit date: | 2009-06-16 | | Release date: | 2009-10-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor.
Angew.Chem.Int.Ed.Engl., 48, 2009
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5WNV
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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3HWE
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4WNX
 | | Netrin 4 lacking the C-terminal Domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | McDougall, M, Patel, T, Reuten, R, Meier, M, Koch, M, Stetefeld, J. | | Deposit date: | 2014-10-14 | | Release date: | 2016-02-10 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.723 Å) | | Cite: | Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.
Nat Commun, 7, 2016
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5ZDQ
 | | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with COLLETOCHLORIN B | | Descriptor: | 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | | Authors: | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | | Deposit date: | 2018-02-23 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Biochim Biophys Acta Bioenerg, 1860, 2019
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7XWE
 | | RRGSGG-AtPRT6 UBR box | | Descriptor: | E3 ubiquitin-protein ligase PRT6, MAGNESIUM ION, ZINC ION | | Authors: | Kim, L, Song, H.K. | | Deposit date: | 2022-05-26 | | Release date: | 2023-05-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.598 Å) | | Cite: | Structural analyses of plant PRT6-UBR box for Cys-Arg/N-degron pathway and insights into the plant submergence resistance
To Be Published
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7XWG
 | | RSGSGG-AtPRT6 UBR box | | Descriptor: | E3 ubiquitin-protein ligase PRT6, ZINC ION | | Authors: | Kim, L, Song, H.K. | | Deposit date: | 2022-05-26 | | Release date: | 2023-05-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.832 Å) | | Cite: | Structural analyses of plant PRT6-UBR box for Cys-Arg/N-degron pathway and insights into the plant submergence resistance
To Be Published
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4Y83
 | | Crystal structure of COT kinase domain in complex with 5-(2-amino-5-(quinolin-3-yl)pyridin-3-yl)-1,3,4-oxadiazole-2(3H)-thione | | Descriptor: | 5-[2-amino-5-(quinolin-3-yl)pyridin-3-yl]-1,3,4-oxadiazole-2(3H)-thione, Mitogen-activated protein kinase kinase kinase 8 | | Authors: | Gutmann, S, Hinniger, A. | | Deposit date: | 2015-02-16 | | Release date: | 2015-05-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold.
J.Biol.Chem., 290, 2015
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7XWF
 | | RLGSGG-AtPRT6 UBR box (highest resolution) | | Descriptor: | E3 ubiquitin-protein ligase PRT6, ZINC ION | | Authors: | Kim, L, Song, H.K. | | Deposit date: | 2022-05-26 | | Release date: | 2023-05-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.451 Å) | | Cite: | Structural analyses of plant PRT6-UBR box for Cys-Arg/N-degron pathway and insights into the plant submergence resistance
To Be Published
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1NAN
 | | MCH CLASS I H-2KB MOLECULE COMPLEXED WITH PBM1 PEPTIDE | | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | | Authors: | Reiser, J.-B, Darnault, C, Gregoire, C, Mosser, T, Mazza, G, Kearnay, A, van der Merwe, P.A, Fontecilla-Camps, J.C, Housset, D, Malissen, B. | | Deposit date: | 2002-11-28 | | Release date: | 2003-03-11 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | CDR3 loop flexibility contributes to the degeneracy of TCR recognition
Nat.Immunol., 4, 2003
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4YB0
 | | 3',3'-cGAMP riboswitch bound with c-di-GMP | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ren, A.M, Patel, D.J, Rajashankar, R.K. | | Deposit date: | 2015-02-18 | | Release date: | 2015-04-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.121 Å) | | Cite: | Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
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3HNE
 | | Crystal structure of human ribonucleotide reductase 1 bound to the effectors TTP and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... | | Authors: | Fairman, J.W, Wijerathna, S.R, Xu, H, Dealwis, C.G. | | Deposit date: | 2009-05-31 | | Release date: | 2011-02-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.11 Å) | | Cite: | Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
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182L
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8CIH
 | | Structure of FL CINP | | Descriptor: | Cyclin-dependent kinase 2-interacting protein, SODIUM ION | | Authors: | Foglizzo, M, Zeqiraj, E. | | Deposit date: | 2023-02-09 | | Release date: | 2024-02-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity.
Cell, 187, 2024
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3HVJ
 | | Rat catechol O-methyltransferase in complex with a catechol-type, N6-propyladenine-containing bisubstrate inhibitor | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ... | | Authors: | Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. | | Deposit date: | 2009-06-16 | | Release date: | 2009-10-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor.
Angew.Chem.Int.Ed.Engl., 48, 2009
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3LLS
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8CCN
 | | Filamentous actin II from Plasmodium falciparum | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-2, MAGNESIUM ION | | Authors: | Kursula, I, Lopez, A.J. | | Deposit date: | 2023-01-27 | | Release date: | 2023-02-22 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and function of Plasmodium actin II in the parasite mosquito stages.
Plos Pathog., 19, 2023
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8CCO
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1O68
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8C03
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation | | Descriptor: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 | | Authors: | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | Deposit date: | 2022-12-15 | | Release date: | 2023-03-22 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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5TUE
 | | Crystal structure of tetracycline destructase Tet(50) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Tetracycline destructase Tet(50) | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2016-11-05 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
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