435D
 
 | | 5'-R(*UP*AP*GP*CP*CP*CP*C)-3', 5'-R(*GP*GP*GP*GP*CP*UP*A)-3' | | Descriptor: | RNA (5'-R(*GP*GP*GP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*CP*CP*C)-3'), SODIUM ION | | Authors: | Mueller, U, Schuebel, H, Sprinzl, M, Heinemann, U. | | Deposit date: | 1998-10-23 | | Release date: | 1999-06-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of acceptor stem of tRNA(Ala) from Escherichia coli shows unique G.U wobble base pair at 1.16 A resolution.
RNA, 5, 1999
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434D
 | | 5'-R(*UP*AP*GP*CP*UP*CP*C)-3', 5'-R(*GP*GP*GP*GP*CP*UP*A)-3' | | Descriptor: | RNA (5'-R(*GP*GP*GP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3'), SODIUM ION, ... | | Authors: | Mueller, U, Schuebel, H, Sprinzl, M, Heinemann, U. | | Deposit date: | 1998-10-23 | | Release date: | 1999-06-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | Crystal structure of acceptor stem of tRNA(Ala) from Escherichia coli shows unique G.U wobble base pair at 1.16 A resolution.
RNA, 5, 1999
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1ZDI
 | | RNA BACTERIOPHAGE MS2 COAT PROTEIN/RNA COMPLEX | | Descriptor: | PROTEIN (RNA BACTERIOPHAGE MS2 COAT PROTEIN), RNA (5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP*UP*AP*CP*CP*CP*AP*U P*GP*U)-3') | | Authors: | Valegard, K, Van Den Worm, S, Liljas, L. | | Deposit date: | 1996-09-24 | | Release date: | 1997-04-21 | | Last modified: | 2023-04-19 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The three-dimensional structures of two complexes between recombinant MS2 capsids and RNA operator fragments reveal sequence-specific protein-RNA interactions.
J.Mol.Biol., 270, 1997
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8AMK
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8AMN
 | | Crystal structure of AUGUGGCAU duplex with strontium ions | | Descriptor: | RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), STRONTIUM ION | | Authors: | Kiliszek, A, Rypniewski, W. | | Deposit date: | 2022-08-03 | | Release date: | 2022-11-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair.
Rna, 29, 2022
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3P2J
 | | Crystal structure of peptidyl-tRNA hydrolase from Mycobacterium smegmatis at 2.2 A resolution | | Descriptor: | Peptidyl-tRNA hydrolase | | Authors: | Kumar, A, Singh, A, Yadav, R, Sinha, M, Arora, A, Sharma, S, Singh, T.P. | | Deposit date: | 2010-10-02 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Crystal Structure of peptidyl-tRNA hydrolase from Mycobacterium smegmatis at 2.2 A resolution
To be Published
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3G98
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2L9B
 | | Heterodimer between Rna14p monkeytail domain and Rna15p hinge domain of the yeast CF IA complex | | Descriptor: | mRNA 3'-end-processing protein RNA14, mRNA 3'-end-processing protein RNA15 | | Authors: | Moreno-Morcillo, M, Minvielle-Sebastia, L, Fribourg, S, Mackereth, C.D. | | Deposit date: | 2011-02-07 | | Release date: | 2011-04-27 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Locked Tether Formation by Cooperative Folding of Rna14p Monkeytail and Rna15p Hinge Domains in the Yeast CF IA Complex.
Structure, 19, 2011
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6NLQ
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6NLY
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6NOW
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479D
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8K9X
 | | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 5 (ADKI5) | | Descriptor: | (2~{S})-2,6-bis(azanyl)-~{N}-[3-[2-[[4-[(2,5-dimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]phenyl]sulfonylpropyl]hexanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lysine--tRNA ligase | | Authors: | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | | Deposit date: | 2023-08-01 | | Release date: | 2024-06-26 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors.
Commun Biol, 7, 2024
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8K9V
 | | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 3 (ADKI3) | | Descriptor: | GLYCEROL, LYSINE, Lysine--tRNA ligase, ... | | Authors: | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | | Deposit date: | 2023-08-01 | | Release date: | 2024-06-26 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors.
Commun Biol, 7, 2024
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8K9S
 | | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 1 (ADKI1) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LYSINE, Lysine--tRNA ligase, ... | | Authors: | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | | Deposit date: | 2023-08-01 | | Release date: | 2024-06-26 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors.
Commun Biol, 7, 2024
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8K9W
 | | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 4 (ADKI4) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lysine--tRNA ligase, ~{N}2-(2-methoxyphenyl)-~{N}4-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine | | Authors: | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | | Deposit date: | 2023-08-01 | | Release date: | 2024-06-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors.
Commun Biol, 7, 2024
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8K9U
 | | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 2 (ADKI2) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LYSINE, Lysine--tRNA ligase, ... | | Authors: | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | | Deposit date: | 2023-08-01 | | Release date: | 2024-06-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors.
Commun Biol, 7, 2024
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6ILD
 | | Crystal Structure of Human LysRS: P38/AIMP2 Complex II | | Descriptor: | 5'-O-[(S)-hydroxy(methyl)phosphoryl]adenosine, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, ... | | Authors: | Hei, Z, Liu, Z, Wang, J, Fang, P. | | Deposit date: | 2018-10-17 | | Release date: | 2019-02-27 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.882 Å) | | Cite: | Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.
J. Biol. Chem., 294, 2019
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485D
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6MTK
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1G2J
 | | RNA OCTAMER R(CCCP*GGGG) CONTAINING PHENYL RIBONUCLEOTIDE | | Descriptor: | 5'-R(*CP*CP*CP*(PYY)P*GP*GP*GP*G)-3', CALCIUM ION | | Authors: | Minasov, G, Matulic-Adamic, J, Wilds, C.J, Haeberli, P, Usman, N, Beigelman, L, Egli, M. | | Deposit date: | 2000-10-20 | | Release date: | 2000-12-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines.
RNA, 6, 2000
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2PY9
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8TC9
 | | Human asparaginyl-tRNA synthetase bound to OSM-S-106 | | Descriptor: | Asparagine--tRNA ligase, cytoplasmic, GLYCEROL, ... | | Authors: | Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | | Deposit date: | 2023-06-30 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
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8TC7
 | | Human asparaginyl-tRNA synthetase, apo form | | Descriptor: | Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ... | | Authors: | Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | | Deposit date: | 2023-06-30 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
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7XOF
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