PDB: 292 resultsInfo pagesStatus searchChemie searchBIRD

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2KDK	Structure of human circadian clock protein BMAL2 C-terminal PAS domain Descriptor: Aryl hydrocarbon receptor nuclear translocator-like protein 2 Authors: Wasielewski, E, Correia, C, Prendergast, F.G, Mer, G. Deposit date: 2009-01-10 Release date: 2011-04-13 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of human circadian clock protein BMAL2 C-terminal PAS domain To be Published
2DQL	Crystal structure of the circadian clock associated protein Pex from anabaena Descriptor: PHOSPHATE ION, Pex protein Authors: Kurosawa, S, Kouyama, T. Deposit date: 2006-05-29 Release date: 2007-05-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Functionally important structural elements of the cyanobacterial clock-related protein Pex. Genes Cells, 14, 2009
7V8Y	Crystal structure of mouse CRY2 in complex with SHP1703 compound Descriptor: 1-[(2R)-3-[3,6-bis(fluoranyl)carbazol-9-yl]-2-oxidanyl-propyl]imidazolidin-2-one, Cryptochrome-2 Authors: Miller, S.A, Hirota, T. Deposit date: 2021-08-23 Release date: 2022-08-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy. Proc.Natl.Acad.Sci.USA, 119, 2022
7V8Z	Crystal structure of mouse CRY2 in complex with SHP656 compound Descriptor: 1-[(2R)-3-[3,6-bis(fluoranyl)carbazol-9-yl]-2-oxidanyl-propyl]imidazolidin-2-one, Cryptochrome-2 Authors: Miller, S.A, Hirota, T. Deposit date: 2021-08-23 Release date: 2022-08-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy. Proc.Natl.Acad.Sci.USA, 119, 2022
8JON	Structure of a synthetic circadian clock protein KaiC mutant of cyanobacteria Synechococcus elongatus PCC 7942 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, ... Authors: Jia, X, Zhang, Q, Li, S, Guo, J. Deposit date: 2023-06-07 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (2.51 Å) Cite: Adaptation of ancient cyanobacterial clock to the day length ~ 0.95 Ga ago To Be Published
7D1C	Crystal structure of mouse Cryptochrome 1 in complex with compound TH303 Descriptor: Cryptochrome-1, N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-4-(phenylcarbonyl)benzamide Authors: Miller, S.A, Hirota, T. Deposit date: 2020-09-14 Release date: 2021-01-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock. J.Am.Chem.Soc., 143, 2021
7D19	Crystal structure of mouse Cryptochrome 1 in complex with compound TH129 Descriptor: Cryptochrome-1, N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-4-(phenylcarbonyl)benzamide Authors: Miller, S.A, Hirota, T. Deposit date: 2020-09-14 Release date: 2021-01-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock. J.Am.Chem.Soc., 143, 2021
7DYE	Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION Authors: Furuike, Y, Akiyama, S. Deposit date: 2021-01-21 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Regulation mechanisms of the dual ATPase in KaiC. Proc.Natl.Acad.Sci.USA, 119, 2022
4DJ2	Unwinding the Differences of the Mammalian PERIOD Clock Proteins from Crystal Structure to Cellular Function Descriptor: Period circadian protein homolog 1 Authors: Kucera, N, Schmalen, I, Hennig, S, Oellinger, R, Strauss, H.M, Grudziecki, A, Wieczorek, C, Kramer, A, Wolf, E. Deposit date: 2012-02-01 Release date: 2012-02-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function. Proc.Natl.Acad.Sci.USA, 109, 2012
4DJ3	Unwinding the Differences of the Mammalian PERIOD Clock Proteins from Crystal Structure to Cellular Function Descriptor: Period circadian protein homolog 3 Authors: Wolf, E, Kucera, N, Hennig, S. Deposit date: 2012-02-01 Release date: 2012-02-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function. Proc.Natl.Acad.Sci.USA, 109, 2012
7DY1	Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION Authors: Furuike, Y, Akiyama, S. Deposit date: 2021-01-20 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Regulation mechanisms of the dual ATPase in KaiC. Proc.Natl.Acad.Sci.USA, 119, 2022
3GDI	Mammalian Clock Protein mPER2 - Crystal Structure of a PAS Domain Fragment Descriptor: Period circadian protein homolog 2 Authors: Hennig, S, Wolf, E. Deposit date: 2009-02-24 Release date: 2009-05-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2. Plos Biol., 7, 2009
1T4Z	Solution structure of the N-terminal domain of Synechococcus elongatus SasA (25-structures ensemble) Descriptor: Adaptive-response sensory-kinase sasA Authors: Vakonakis, I, Klewer, D.A, LiWang, A.C. Deposit date: 2004-04-30 Release date: 2004-11-16 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure of the N-terminal domain of the circadian clock-associated histidine kinase SasA. J.Mol.Biol., 342, 2004
1T4Y	Solution structure of the N-terminal domain of Synechococcus elongatus SasA (average minimized structure) Descriptor: Adaptive-response sensory-kinase sasA Authors: Vakonakis, I, Klewer, D.A, LiWang, A.C. Deposit date: 2004-04-30 Release date: 2004-11-16 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure of the N-terminal domain of the circadian clock-associated histidine kinase SasA. J.Mol.Biol., 342, 2004
4U8H	Crystal Structure of Mammalian Period-Cryptochrome Complex Descriptor: Cryptochrome-2, Period circadian protein homolog 2, ZINC ION Authors: Nangle, S.N, Rosensweig, C, Koike, N, Tei, H, Takahashi, J.S, Green, C.B, Zheng, N. Deposit date: 2014-08-03 Release date: 2014-10-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.798 Å) Cite: Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex. Elife, 3, 2014
5T5X	High resolution structure of mouse Cryptochrome 1 Descriptor: CHLORIDE ION, Cryptochrome-1 Authors: Michael, A.K, Tripathi, S, Partch, C.L. Deposit date: 2016-08-31 Release date: 2017-02-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4O0M	Crystal structure of T. Elongatus BP-1 Clock Protein KaiC Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION Authors: Pattanayek, R, Egli, M. Deposit date: 2013-12-13 Release date: 2014-05-14 Method: X-RAY DIFFRACTION (2.84 Å) Cite: An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC Acta Crystallogr.,Sect.D, D70, 2014
1WA9	Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD Descriptor: PERIOD CIRCADIAN PROTEIN Authors: Yildiz, O, Doi, M, Yujnovsky, I, Cardone, L, Berndt, A, Hennig, S, Schulze, S, Urbanke, C, Sassone-Corsi, P, Wolf, E. Deposit date: 2004-10-25 Release date: 2005-01-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Crystal Structure and Interactions of the Pas Repeat Region of the Drosophila Clock Protein Period Mol.Cell, 17, 2005
3GEC	Crystal structure of a tandem PAS domain fragment of Drosophila PERIOD Descriptor: Period circadian protein Authors: Yildiz, O, Wolf, E. Deposit date: 2009-02-25 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (4 Å) Cite: Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2 Plos Biol., 7, 2009
6OF7	Crystal structure of the CRY1-PER2 complex Descriptor: Cryptochrome-1, Period circadian protein homolog 2 Authors: Michael, A.K, Fribourgh, J.L, Tripathi, S.M, Partch, C.L. Deposit date: 2019-03-28 Release date: 2020-03-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. Elife, 9, 2020
2ZFW	Crystal structure of Pex from Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Descriptor: Pex, SULFATE ION Authors: Kouyama, T. Deposit date: 2008-01-14 Release date: 2009-01-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Functionally important structural elements of the cyanobacterial clock-related protein Pex. Genes Cells, 14, 2009
5SVU	Structure and kinetics of the LOV domain of ZEITLUPE determine its circadian function in Arabidopsis Descriptor: Adagio protein 1, FLAVIN MONONUCLEOTIDE Authors: Zoltowski, B, Pudasaini, A. Deposit date: 2016-08-07 Release date: 2017-03-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Kinetics of the LOV domain of ZEITLUPE determine its circadian function inArabidopsis. Elife, 6, 2017
5SVG	Structure and kinetics of the LOV domain of ZEITLUPE determine its circadian function in Arabidopsis Descriptor: Adagio protein 1, FLAVIN MONONUCLEOTIDE Authors: Zoltowski, B, Pudasaini, A. Deposit date: 2016-08-05 Release date: 2017-03-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Kinetics of the LOV domain of ZEITLUPE determine its circadian function inArabidopsis. Elife, 6, 2017
5SVV	Structure and kinetics of the LOV domain of ZEITLUPE determine its circadian function in Arabidopsis Descriptor: ACETATE ION, Adagio protein 1, FLAVIN MONONUCLEOTIDE, ... Authors: Zoltowski, B, Pudasaini, A. Deposit date: 2016-08-07 Release date: 2017-03-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.101 Å) Cite: Kinetics of the LOV domain of ZEITLUPE determine its circadian function inArabidopsis. Elife, 6, 2017
6K0R	Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Zhang, W, Chen, L, Li, W, Ju, D, Huang, N, Zhang, E. Deposit date: 2019-05-07 Release date: 2020-05-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals. Sci Transl Med, 12, 2020

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