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8G5Z
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BU of 8g5z by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G6J
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BU of 8g6j by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Descriptor: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-15
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G60
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BU of 8g60 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G61
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BU of 8g61 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8GLP
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BU of 8glp by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C.
Deposit date:2023-03-22
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.67 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G5Y
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BU of 8g5y by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
7Z1L
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BU of 7z1l by Molmil
Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
Descriptor: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
Authors:Girbig, M, Mueller, C.W.
Deposit date:2022-02-24
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z1O
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BU of 7z1o by Molmil
Structure of yeast RNA Polymerase III PTC + NTPs
Descriptor: CHAPSO, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
Authors:Girbig, M, Mueller, C.W.
Deposit date:2022-02-24
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z1M
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BU of 7z1m by Molmil
Structure of yeast RNA Polymerase III Elongation Complex (EC)
Descriptor: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
Authors:Girbig, M, Mueller, C.W.
Deposit date:2022-02-24
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z1N
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BU of 7z1n by Molmil
Structure of yeast RNA Polymerase III Delta C53-C37-C11
Descriptor: CHAPSO, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Girbig, M, Mueller, C.W.
Deposit date:2022-02-24
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
6T0W
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BU of 6t0w by Molmil
Human Influenza B polymerase recycling complex
Descriptor: Polymerase PB2, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ...
Authors:Wandzik, J.M, Kouba, T, Karuppasamy, M, Cusack, S.
Deposit date:2019-10-03
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6KV5
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BU of 6kv5 by Molmil
Structure of influenza D virus apo polymerase
Descriptor: Polymerase 3, Polymerase PB2, RNA-directed RNA polymerase catalytic subunit
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-03
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6T0R
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BU of 6t0r by Molmil
Bat Influenza A polymerase product dissociation complex using 44-mer vRNA template with mutated oligo(U) sequence
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2019-10-03
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6T0U
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BU of 6t0u by Molmil
Bat Influenza A polymerase product dissociation complex using 44-mer vRNA template with intact oligo(U) sequence
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2019-10-03
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6GZ3
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BU of 6gz3 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
8R65
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BU of 8r65 by Molmil
1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2023-11-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
To Be Published
8R60
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BU of 8r60 by Molmil
1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
Deposit date:2023-11-19
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
To Be Published
5EPI
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BU of 5epi by Molmil
CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT
Descriptor: CRNA 5' END, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Guilligay, D, Cusack, S.
Deposit date:2015-11-11
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.
Mol.Cell, 61, 2016
2E9Z
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BU of 2e9z by Molmil
Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP
Descriptor: 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2007-01-29
Release date:2007-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
6EVJ
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BU of 6evj by Molmil
Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primer
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(GDM))-R(P*AP*AP*U)-3'), ...
Authors:Pflug, A, Cusack, S.
Deposit date:2017-11-01
Release date:2017-12-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
4M6T
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BU of 4m6t by Molmil
Structure of human Paf1 and Leo1 complex
Descriptor: RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ...
Authors:Shen, Y, Qin, X.
Deposit date:2013-08-11
Release date:2013-10-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
1YKE
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BU of 1yke by Molmil
Structure of the mediator MED7/MED21 subcomplex
Descriptor: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
Authors:Baumli, S, Hoeppner, S, Cramer, P.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
1YKH
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BU of 1ykh by Molmil
Structure of the mediator MED7/MED21 (Med7/Srb7) subcomplex
Descriptor: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
Authors:Baumli, S, Hoeppner, S, Cramer, P.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
3KYH
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BU of 3kyh by Molmil
Saccharomyces cerevisiae Cet1-Ceg1 capping apparatus
Descriptor: mRNA-capping enzyme subunit alpha, mRNA-capping enzyme subunit beta
Authors:Lima, C.D.
Deposit date:2009-12-06
Release date:2010-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus.
Structure, 18, 2010
2HZS
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BU of 2hzs by Molmil
Structure of the Mediator head submodule Med8C/18/20
Descriptor: RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8
Authors:Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
Deposit date:2006-08-09
Release date:2006-09-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006

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