PDB: 762 resultsInfo pagesStatus searchChemie searchBIRD

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8JNK	Crystal structure of human ALKBH3 bound to ssDNA through active site crosslink Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ... Authors: Zhang, L. Deposit date: 2023-06-06 Release date: 2024-01-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.69 Å) Cite: The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation. Angew.Chem.Int.Ed.Engl., 63, 2024
8JNR	Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ... Authors: Zhang, L. Deposit date: 2023-06-06 Release date: 2024-01-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.66 Å) Cite: The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation. Angew.Chem.Int.Ed.Engl., 63, 2024
8JKK	Crystal Structure of the dioxygenase CcTet from Coprinopsis cinerea bound to 12bp 5-methylcytosine (5mC) containing duplex DNA Descriptor: 2OGFeDO JBP1/TET oxygenase domain-containing protein, DNA (5'-D(P*CP*GP*AP*TP*CP*(5CM)P*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*AP*GP*CP*TP*GP*AP*TP*CP*G)-3'), ... Authors: Zhang, L, Zhang, L. Deposit date: 2023-06-01 Release date: 2024-03-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular basis of an atypical dsDNA 5mC/6mA bifunctional dioxygenase CcTet from Coprinopsis cinerea in catalyzing dsDNA 5mC demethylation. Nucleic Acids Res., 52, 2024
7UJV	Structure of PHD2 in complex with HIF2a-CODD Descriptor: Egl nine homolog 1, Endothelial PAS domain-containing protein 1, FE (III) ION, ... Authors: Ferens, F.G, Tarade, D, Lee, J.E, Ohh, M. Deposit date: 2022-03-31 Release date: 2023-04-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Deficiency in PHD2-mediated hydroxylation of HIF2 alpha underlies Pacak-Zhuang syndrome. Commun Biol, 7, 2024
7VPN	Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain in complex with Mn(II) and N-Oxalylglycine Descriptor: CcTet molecule, MANGANESE (II) ION, N-OXALYLGLYCINE Authors: Mu, Y.J, Zhang, L, Zhang, L. Deposit date: 2021-10-17 Release date: 2022-03-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat.Chem.Biol., 18, 2022
6BYK	Structure of 14-3-3 beta/alpha bound to O-ClcNAc peptide Descriptor: 14-3-3 protein beta/alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATPPVSQASSTT O-GlcNac peptide Authors: Schumacher, M.A. Deposit date: 2017-12-20 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018
7WL0	Crystal structure of human ALKBH5 in complex with N-oxalylglycine (NOG) and m6A-containing ssRNA Descriptor: FORMIC ACID, MANGANESE (II) ION, N-OXALYLGLYCINE, ... Authors: Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S. Deposit date: 2022-01-12 Release date: 2022-03-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes. Nucleic Acids Res., 50, 2022
7W5P	Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA Descriptor: CcTet, DNA, DNA (12-MER), ... Authors: Mu, Y.J, Zhang, L, Zhang, L. Deposit date: 2021-11-30 Release date: 2022-03-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat.Chem.Biol., 18, 2022
7VBQ	Heterodimer structure of Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxIJ Descriptor: FE (III) ION, Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxI, Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxJ, ... Authors: Li, X, Awakawa, T, Mori, T, Abe, I. Deposit date: 2021-09-01 Release date: 2022-04-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. J.Am.Chem.Soc., 143, 2021
2Q8C	Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate Descriptor: 2-OXOGLUTARIC ACID, HISTONE 3 PEPTIDE, JmjC domain-containing histone demethylation protein 3A, ... Authors: Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C. Deposit date: 2007-06-10 Release date: 2007-07-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.047 Å) Cite: Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat.Struct.Mol.Biol., 14, 2007
5DIY	Thermobaculum terrenum O-GlcNAc hydrolase mutant - D120N Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hyaluronidase, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Authors: Ostrowski, A, Gundogdu, M, Ferenbach, A.T, Lebedev, A, van Aalten, D.M.F. Deposit date: 2015-09-01 Release date: 2015-10-28 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Evidence for a Functional O-Linked N-Acetylglucosamine (O-GlcNAc) System in the Thermophilic Bacterium Thermobaculum terrenum. J.Biol.Chem., 290, 2015
8H68	Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II) Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Shi, Y, Ding, J, Yang, H. Deposit date: 2022-10-16 Release date: 2023-02-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Caenorhabditis elegans NMAD-1 functions as a demethylase for actin. J Mol Cell Biol, 15, 2023

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