PDB: 162184 resultsInfo pagesStatus searchChemie searchBIRD

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8Q7P	Tau - AD-MIA8 (intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-16 Release date: 2023-08-30 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8QCR	Tau - CTE-MIA12 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-28 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q99	Tau - CTE-MIA10 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9H	Tau - CTE-LIA4 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.18 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q97	Tau - CTE-MIA9 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9D	Tau - CTE-MIA15 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q98	Tau - CTE-MIA8 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (1.75 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8L	Tau - AD-LIA7 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-18 Release date: 2023-09-20 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8F	Tau - AD-LIA5 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-18 Release date: 2023-09-20 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8U	Tau - CTE-MIA1 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-18 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8W	Tau - CTE-MIA4 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-19 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9C	Tau - CTE-MIA14 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8Y	Tau - CTE-MIA6 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-19 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9E	Tau - CTE-MIA18 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8Z	Tau - CTE-MIA7 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-19 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9A	Tau - CTE-MIA11 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8E	Tau - AD-LIA4 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-18 Release date: 2023-09-20 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.81 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q8X	Tau - CTE-MIA5 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-19 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9B	Tau - CTE-MIA13 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-20 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8QJJ	CTE type II (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Scheres, S.H.W. Deposit date: 2023-09-13 Release date: 2023-10-18 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
6UQU	Serendipitous Discovery of Aryl Boronic Acids as beta-Lactamase Inhibitors Descriptor: Beta-lactamase, CHLORIDE ION, PHENYL BORONIC ACID Authors: Scapin, G. Deposit date: 2019-10-21 Release date: 2019-10-30 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.0902 Å) Cite: Serendipitous discovery of aryl boronic acids as beta-lactamase inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
6UR3	Serendipitous Discovery of Aryl Boronic Acids as beta-Lactamase Inhibitors Descriptor: 1,2-ETHANEDIOL, 2-hydroxyethyl hydrogen phenylboronate, Beta-lactamase, ... Authors: Scapin, G. Deposit date: 2019-10-22 Release date: 2019-10-30 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.423 Å) Cite: Serendipitous discovery of aryl boronic acids as beta-lactamase inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
4JZR	Structure of Prolyl Hydroxylase Domain-containing Protein (PHD) with Inhibitors Descriptor: 1,2-ETHANEDIOL, 2-(biphenyl-4-yl)-8-[(1-methyl-1H-imidazol-2-yl)methyl]-2,8-diazaspiro[4.5]decan-1-one, Egl nine homolog 1, ... Authors: Ma, Y, Yang, L. Deposit date: 2013-04-03 Release date: 2013-10-30 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors Bioorg.Med.Chem., 21, 2013
1YL8	3D Solution Structure of [Tyr3]Octreotate derivatives in DMSO Descriptor: [Tyr3]Octreotate peptide Authors: Spyroulias, G.A, Galanis, A.S, Petrou, C, Vahliotis, D, Sotiriou, P, Nikolopoulou, A, Nock, B, Maina, T, Cordopatis, P. Deposit date: 2005-01-19 Release date: 2005-09-20 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: 3D solution structure of [Tyr3]octreotate derivatives in DMSO: structure differentiation of peptide core due to chelate group attachment and biologically active conformation. Med.Chem., 1, 2005
1YL9	3D Solution Structure of [Tyr3]Octreotate derivatives in DMSO Descriptor: 3-[(2-AMINOETHYL)AMINO]-2-{[(2-AMINOETHYL)AMINO]METHYL}PROPANAL, [Tyr3]Octreotate Authors: Spyroulias, G.A, Galanis, A.S, Petrou, C, Vahliotis, D, Sotiriou, P, Nikolopoulou, A, Nock, B, Maina, T, Cordopatis, P. Deposit date: 2005-01-19 Release date: 2005-09-20 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: 3D solution structure of [Tyr3]octreotate derivatives in DMSO: structure differentiation of peptide core due to chelate group attachment and biologically active conformation. Med.Chem., 1, 2005

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