PDB: 533 resultsInfo pagesStatus searchChemie searchBIRD

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2H8H	Src kinase in complex with a quinazoline inhibitor Descriptor: N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src Authors: Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. Deposit date: 2006-06-07 Release date: 2006-11-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J.Med.Chem., 49, 2006
2HCK	SRC FAMILY KINASE HCK-QUERCETIN COMPLEX Descriptor: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, CALCIUM ION, HEMATOPOETIC CELL KINASE HCK Authors: Sicheri, F, Moarefi, I, Kuriyan, J. Deposit date: 1997-02-25 Release date: 1997-08-20 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of the Src family tyrosine kinase Hck. Nature, 385, 1997
2EYZ	CT10-Regulated Kinase isoform II Descriptor: v-crk sarcoma virus CT10 oncogene homolog isoform a Authors: Kobashigawa, Y, Tanaka, S, Inagaki, F. Deposit date: 2005-11-10 Release date: 2006-11-10 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2DVJ	phosphorylated Crk-II Descriptor: V-crk sarcoma virus CT10 oncogene homolog, isoform a Authors: Kobashigawa, Y, Inagaki, F. Deposit date: 2006-07-31 Release date: 2007-05-08 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2LQN	Solution structure of CRKL Descriptor: Crk-like protein Authors: Jankowski, W, Saleh, T, Kalodimos, C. Deposit date: 2012-03-09 Release date: 2012-05-16 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LQW	Solution structure of phosphorylated CRKL Descriptor: Crk-like protein Authors: Jankowski, W, Saleh, T, Kalodimos, C. Deposit date: 2012-03-16 Release date: 2012-05-16 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2K79	Solution Structure of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase Descriptor: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK Authors: Andreotti, A.H, Severin, A.J, Fulton, D.B. Deposit date: 2008-08-08 Release date: 2009-03-10 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009
2K7A	Ensemble Structures of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase. Descriptor: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK Authors: Andreotti, A.H, Severin, A.J, Fulton, D.B. Deposit date: 2008-08-08 Release date: 2009-03-10 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009

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