3NQ0
 
 | | Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of Zinc | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2010-06-29 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity.
J.Mol.Biol., 405, 2011
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3NTM
 | | Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of zinc, partial occupancy of CuB | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2010-07-05 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity
J.Mol.Biol., 405, 2011
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3NPY
 | | Crystal Structure of Tyrosinase from Bacillus megaterium soaked in CuSO4 | | Descriptor: | CHLORIDE ION, COPPER (II) ION, Tyrosinase, ... | | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2010-06-29 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.192 Å) | | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity.
J.Mol.Biol., 405, 2011
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3NM8
 | | Crystal structure of Tyrosinase from Bacillus megaterium | | Descriptor: | CHLORIDE ION, COPPER (II) ION, Tyrosinase, ... | | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2010-06-22 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity
J.Mol.Biol., 405, 2011
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4HD6
 | | Crystal Structure of Tyrosinase from Bacillus megaterium V218F mutant soaked in CuSO4 | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2012-10-02 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase.
Biochim.Biophys.Acta, 1834, 2013
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4HD4
 | | Crystal Structure of Tyrosinase from Bacillus megaterium V218F mutant | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2012-10-02 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase.
Biochim.Biophys.Acta, 1834, 2013
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4J3P
 | | Crystal structure of full-length catechol oxidase from Aspergillus oryzae | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Catechol oxidase, ... | | Authors: | Hakulinen, N, Gasparetti, C, Kaljunen, H, Rouvinen, J. | | Deposit date: | 2013-02-06 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae.
J.Biol.Inorg.Chem., 18, 2013
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4HD7
 | | Crystal Structure of Tyrosinase from Bacillus megaterium V218G mutant soaked in CuSO4 | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | | Deposit date: | 2012-10-02 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase.
Biochim.Biophys.Acta, 1834, 2013
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4J6V
 | | Crystal Structure of Tyrosinase from Bacillus megaterium N205D mutant | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. | | Deposit date: | 2013-02-12 | | Release date: | 2013-12-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The mechanism of copper uptake by tyrosinase from Bacillus megaterium.
J.Biol.Inorg.Chem., 18, 2013
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4J6T
 | | Crystal Structure of Tyrosinase from Bacillus megaterium F197A mutant | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. | | Deposit date: | 2013-02-12 | | Release date: | 2013-12-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | The mechanism of copper uptake by tyrosinase from Bacillus megaterium.
J.Biol.Inorg.Chem., 18, 2013
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4J6U
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4J3R
 | | Crystal structure of catechol oxidase from Aspergillus oryzae, soaked in 4-tert-butylcatechol | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, OXYGEN MOLECULE, ... | | Authors: | Hakulinen, N, Gasparetti, C, Kaljunen, H, Rouvinen, J. | | Deposit date: | 2013-02-06 | | Release date: | 2013-11-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae.
J.Biol.Inorg.Chem., 18, 2013
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4J3Q
 | | Crystal structure of truncated catechol oxidase from Aspergillus oryzae | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | | Authors: | Hakulinen, N, Gasparetti, C, Kaljunen, H, Rouvinen, J. | | Deposit date: | 2013-02-06 | | Release date: | 2013-11-27 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae.
J.Biol.Inorg.Chem., 18, 2013
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6JU6
 | | Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant | | Descriptor: | NITRATE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU9
 | | Aspergillus oryzae active-tyrosinase copper-bound C92A mutant complexed with L-tyrosine | | Descriptor: | 3,4-DIHYDROXYPHENYLALANINE, COPPER (II) ION, NITRATE ION, ... | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU7
 | | Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant complexed with L-tyrosine | | Descriptor: | NITRATE ION, TYROSINE, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU8
 | | Aspergillus oryzae active-tyrosinase copper-bound C92A mutant | | Descriptor: | COPPER (II) ION, NITRATE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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5M8N
 | | Crystal structure of human tyrosinase related protein 1 in complex with mimosine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5M8T
 | | Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with tropolone | | Descriptor: | 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5M8O
 | | Crystal structure of human tyrosinase related protein 1 in complex with tropolone | | Descriptor: | 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5M8L
 | | Crystal structure of human tyrosinase related protein 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5M8S
 | | Crystal structure of human tyrosinase related protein 1 mutant (T391V-R374S-Y362F) in complex with phenylthiourea (PTU) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2018-01-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Phenylthiourea Binding to Human Tyrosinase-Related Protein 1
Int J Mol Sci, 2020
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5M8P
 | | Crystal structure of human tyrosinase related protein 1 in complex with tyrosine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2022-12-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5M8R
 | | Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with mimosine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5M8Q
 | | Crystal structure of human tyrosinase related protein 1 mutant (T391V-R374S-Y362F) in complex with kojic acid | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | | Deposit date: | 2016-10-29 | | Release date: | 2017-07-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
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