7YJR
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7YJQ
| Crystal structure of MCR-1-S treated by auranofin | Descriptor: | GOLD ION, Probable phosphatidylethanolamine transferase Mcr-1 | Authors: | Zhang, Q, Sun, H, Wang, M. | Deposit date: | 2022-07-20 | Release date: | 2023-02-01 | Last modified: | 2023-03-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria. J.Biol.Inorg.Chem., 28, 2023
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7YJS
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7WAA
| Crystal structure of MCR-1-S treated by AgNO3 | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1, SILVER ION | Authors: | Zhang, Q, Wang, M, Sun, H. | Deposit date: | 2021-12-13 | Release date: | 2022-03-16 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Re-sensitization of mcr carrying multidrug resistant bacteria to colistin by silver. Proc.Natl.Acad.Sci.USA, 119, 2022
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5YLF
| MCR-1 complex with D-glucose | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, beta-D-glucopyranose | Authors: | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | Deposit date: | 2017-10-17 | Release date: | 2017-11-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance. FASEB J., 32, 2018
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2W5R
| Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | Descriptor: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | Authors: | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | Deposit date: | 2008-12-11 | Release date: | 2009-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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2W8D
| Distinct and essential morphogenic functions for wall- and lipo- teichoic acids in Bacillus subtilis | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE 2, ... | Authors: | Schirner, K, Marles-Wright, J, Lewis, R.J, Errington, J. | Deposit date: | 2009-01-15 | Release date: | 2009-03-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Distinct and Essential Morphogenic Functions for Wall- and Lipo-Teichoic Acids in Bacillus Subtilis Embo J., 28, 2009
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5YLC
| Crystal Structure of MCR-1 Catalytic Domain | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | Authors: | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | Deposit date: | 2017-10-17 | Release date: | 2017-11-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance. FASEB J., 32, 2018
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4UPH
| Crystal Structure of Phosphonate Monoester Hydrolase of Agrobacterium radiobacter | Descriptor: | CHLORIDE ION, MAGNESIUM ION, SULFATASE (SULFURIC ESTER HYDROLASE) PROTEIN | Authors: | Fischer, G, Loo, B.v, Hyvonen, M, Hollfelder, F. | Deposit date: | 2014-06-17 | Release date: | 2015-07-01 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily. J.Am.Chem.Soc., 141, 2019
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2W5S
| Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | Descriptor: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | Authors: | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | Deposit date: | 2008-12-11 | Release date: | 2009-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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2W5T
| Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | Descriptor: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | Authors: | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | Deposit date: | 2008-12-11 | Release date: | 2009-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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5YLE
| MCR-1 complex with ethanolamine (ETA) | Descriptor: | ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | Authors: | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | Deposit date: | 2017-10-17 | Release date: | 2017-11-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance. FASEB J., 32, 2018
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2W8S
| CRYSTAL STRUCTURE OF A catalytically promiscuous PHOSPHONATE MONOESTER HYDROLASE FROM Burkholderia caryophylli | Descriptor: | FE (III) ION, GLYCEROL, PHOSPHONATE MONOESTER HYDROLASE, ... | Authors: | Jonas, S, van Loo, B, Hyvonen, M, Hollfelder, F. | Deposit date: | 2009-01-19 | Release date: | 2010-02-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | An Efficient, Multiply Promiscuous Hydrolase in the Alkaline Phosphatase Superfamily. Proc.Natl.Acad.Sci.USA, 107, 2010
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4UPL
| Dimeric sulfatase SpAS2 from Silicibacter pomeroyi | Descriptor: | SULFATASE FAMILY PROTEIN, ZINC ION | Authors: | Jonas, S, van Loo, B, Hollfelder, F, Hyvonen, M. | Deposit date: | 2014-06-17 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily. J.Am.Chem.Soc., 141, 2019
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4UOO
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4UOP
| Crystal structure of the lipoteichoic acid synthase LtaP from Listeria monocytogenes | Descriptor: | CHLORIDE ION, LIPOTEICHOIC ACID PRIMASE, MAGNESIUM ION, ... | Authors: | Campeotto, I, Freemont, P, Grundling, A. | Deposit date: | 2014-06-06 | Release date: | 2014-08-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system. J. Biol. Chem., 289, 2014
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4UOR
| Structure of lipoteichoic acid synthase LtaS from Listeria monocytogenes in complex with glycerol phosphate | Descriptor: | (2R)-2,3-dihydroxypropyl phosphate, LIPOTEICHOIC ACID SYNTHASE, MAGNESIUM ION | Authors: | Campeotto, I, Freemont, P, Grundling, A. | Deposit date: | 2014-06-09 | Release date: | 2014-08-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system. J. Biol. Chem., 289, 2014
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4UPI
| Dimeric sulfatase SpAS1 from Silicibacter pomeroyi | Descriptor: | SULFATASE FAMILY PROTEIN, ZINC ION | Authors: | Jonas, S, van Loo, B, Hollfelder, F, Hyvonen, M. | Deposit date: | 2014-06-17 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily. J.Am.Chem.Soc., 141, 2019
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5ZJV
| Crystal structure of the catalytic domain of MCR-1 (cMCR-1) in complex with xylose | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, beta-L-xylopyranose | Authors: | Liu, Z.X, Han, Z, Yu, X.L, Wen, G, Zeng, C. | Deposit date: | 2018-03-22 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal Structure of the Catalytic Domain of MCR-1 (cMCR-1) in Complex with d-Xylose Crystals, 8, 2018
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4UPK
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5ZZU
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6A83
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6A7W
| Structure of a catalytic domain of the colistin resistance enzyme | Descriptor: | Putative integral membrane protein, ZINC ION | Authors: | Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F. | Deposit date: | 2018-07-04 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.988 Å) | Cite: | Structural and functional insights into MCR-2 mediated colistin resistance. Sci China Life Sci, 61, 2018
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2W5Q
| Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE | Authors: | Lu, D, Wormann, M.E, Zhang, X, Scheewind, O, Grundling, A, Freemont, P.S. | Deposit date: | 2008-12-11 | Release date: | 2009-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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2VQR
| Crystal structure of a phosphonate monoester hydrolase from rhizobium leguminosarum: a new member of the alkaline phosphatase superfamily | Descriptor: | ACETATE ION, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Jonas, S, Hyvonen, M, Hollfelder, F. | Deposit date: | 2008-03-18 | Release date: | 2008-09-30 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | A New Member of the Alkaline Phosphatase Superfamily with a Formylglycine Nucleophile: Structural and Kinetic Characterisation of a Phosphonate Monoester Hydrolase/Phosphodiesterase from Rhizobium Leguminosarum. J.Mol.Biol., 384, 2008
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