9G5H
 
 | | p53-Y220C Core Domain Covalently Bound to 2-chloro-5-cyanopyrazine Soaked at 5 mM | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-chloranylpyrazine-2-carbonitrile, ... | | Authors: | Stahlecker, J, Klett, T, Stehle, T, Boeckler, F.M. | | Deposit date: | 2024-07-17 | | Release date: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes
Drug Des Devel Ther, 2025
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9G6U
 | | p53-Y220C Core Domain Covalently Bound to 3,5-Dichloro-6-Ethylpyrazine-2-carbonitirle Soaked at 5 mM | | Descriptor: | 1,2-ETHANEDIOL, 3,5-bis(chloranyl)-6-ethyl-pyrazine-2-carbonitrile, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Stahlecker, J, Klett, T, Stehle, T, Boeckler, F.M. | | Deposit date: | 2024-07-19 | | Release date: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes
Drug Des Devel Ther, 2025
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9G6T
 | | p53-Y220C Core Domain Covalently Bound to 5-Chloro-6-methylpyrazine-2-carbonitrile Soaked at 5 mM | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-chloranyl-6-methyl-pyrazine-2-carbonitrile, ... | | Authors: | Stahlecker, J, Klett, T, Stehle, T, Boeckler, F.M. | | Deposit date: | 2024-07-19 | | Release date: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes
Drug Des Devel Ther, 2025
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