9C48
 
 | | Cryo-EM structure of the full-length human P2X4 receptor in the ATP-bound desensitized state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Shi, H, Ditter, I.A, Oken, A.C, Mansoor, S.E. | | Deposit date: | 2024-06-03 | | Release date: | 2025-01-29 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.
Sci Adv, 11, 2025
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9BQI
 | | Cryo-EM structure of BAY-1797 bound to the full-length human P2X4 receptor in the closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Shi, H, Ditter, I.A, Oken, A.C, Mansoor, S.E. | | Deposit date: | 2024-05-09 | | Release date: | 2025-01-29 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.
Sci Adv, 11, 2025
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9BQH
 | | Cryo-EM structure of the full-length human P2X4 receptor in the apo closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Shi, H, Ditter, I.A, Oken, A.C, Mansoor, S.E. | | Deposit date: | 2024-05-09 | | Release date: | 2025-01-29 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.27 Å) | | Cite: | Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.
Sci Adv, 11, 2025
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