9JBH
 
 | | Cryo-EM structure of the human LYCHOS PLD homodimer | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, Lysosomal cholesterol signaling protein | | Authors: | Yu, S, Liang, L. | | Deposit date: | 2024-08-27 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway.
Nat Commun, 16, 2025
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9JBF
 | | Cryo-EM structure of the human LYCHOS Y57A mutant in complex with cholesteryl hemisuccinate in the contracted state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, ... | | Authors: | Yu, S, Liang, L. | | Deposit date: | 2024-08-27 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway.
Nat Commun, 16, 2025
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9JBJ
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9JBG
 | | Cryo-EM structure of the human LYCHOS in complex with lipids in the expanded state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Lysosomal cholesterol signaling protein, ... | | Authors: | Yu, S, Liang, L. | | Deposit date: | 2024-08-27 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.76 Å) | | Cite: | Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway.
Nat Commun, 16, 2025
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9JBI
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9JBE
 | | Cryo-EM structure of the human LYCHOS in complex with cholesterol and cholesteryl hemisuccinate in the contracted state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, ... | | Authors: | Yu, S, Liang, L. | | Deposit date: | 2024-08-27 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway.
Nat Commun, 16, 2025
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