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PDB: 1 results
4FZ7
Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide
Descriptor:
6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK
Authors:
Kuglstatter, A
,
Slade, M.
Deposit date:
2012-07-06
Release date:
2013-07-10
Last modified:
2023-09-13
Method:
X-RAY DIFFRACTION (1.75 Å)
Cite:
Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
J. Med. Chem., 57, 2014
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건을2024-11-13부터공개중