PDB Search results for query - 일본 단백질구조 데이터 뱅크

PDB: 2 results

crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with N-(N-(4-amino-3,5- dichlorobenzyl)carbamimidoyl)-3-(4-methoxyphenyl)-5- methyl-4-isothiazolecarboxamide
Descriptor:	Beta-secretase 1, IODIDE ION, N-[N-(4-amino-3,5-dichlorobenzyl)carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
Authors:	Muckelbauer, J.K.
Deposit date:	2012-06-27
Release date:	2012-10-10
Last modified:	2019-07-17
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Acyl guanidine inhibitors of beta-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesis J.Med.Chem., 55, 2012

Crystal structure of beta-site app-cleaving enzyme 1 (BACE-DB-MUT) complex with N-(N-(4- acetamido-3-chloro-5-methylbenzyl)carbamimidoyl)-3-(4- methoxyphenyl)-5-methyl-4-isothiazolecarboxamide
Descriptor:	Beta-secretase 1, IODIDE ION, N-{N-[4-(acetylamino)-3-chloro-5-methylbenzyl]carbamimidoyl}-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
Authors:	Muckelbauer, J.K.
Deposit date:	2012-06-27
Release date:	2012-10-10
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Acyl Guanidine Inhibitors of beta-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis J.Med.Chem., 55, 2012