8SNL
 
 | | Structure of human ADAM17/iRhom2 sheddase complex | | Descriptor: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2, ... | | Authors: | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | Deposit date: | 2023-04-27 | | Release date: | 2024-05-29 | | Last modified: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Mol.Cell, 84, 2024
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8SNN
 | | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 1 | | Descriptor: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2 | | Authors: | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | Deposit date: | 2023-04-27 | | Release date: | 2024-05-29 | | Last modified: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (2.32 Å) | | Cite: | Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Mol.Cell, 84, 2024
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8SNO
 | | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 2 | | Descriptor: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2 | | Authors: | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | Deposit date: | 2023-04-27 | | Release date: | 2024-05-29 | | Last modified: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Mol.Cell, 84, 2024
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8SNM
 | | Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain | | Descriptor: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Disintegrin and metalloproteinase domain-containing protein 17 propeptide, ... | | Authors: | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | Deposit date: | 2023-04-27 | | Release date: | 2024-05-29 | | Last modified: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Mol.Cell, 84, 2024
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