PDB Search results for query - 일본 단백질구조 데이터 뱅크

PDB: 2 results

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Descriptor:	N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2
Authors:	Ultsch, M.H, Magnuson, S.
Deposit date:	2017-06-26
Release date:	2017-09-06
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model. Bioorg. Med. Chem. Lett., 27, 2017

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Descriptor:	N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Tyrosine-protein kinase JAK2
Authors:	Ultsch, M.H, Magnuson, S.
Deposit date:	2017-07-10
Release date:	2017-09-06
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.854 Å)
Cite:	Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model. Bioorg. Med. Chem. Lett., 27, 2017