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HIV-1 wild Type protease with GRL-0648A (a isophthalamide-derived P2-Ligand)
Descriptor: CHLORIDE ION, GLYCEROL, N-[(2,5-dimethyl-1,3-oxazol-4-yl)methyl]-N'-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]-N,5-dimethylbenzene-1,3-dicarboxamide, ...
Authors:Wang, Y.-F, Agniswamy, J, Weber, I.T.
Deposit date:2015-04-28
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands.
Bioorg.Med.Chem.Lett., 25, 2015

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건을2024-07-10부터공개중

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