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PDB: 2 results

4JJS
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BU of 4jjs by Molmil
Crystal structure of HCV NS5B polymerase in complex with COMPOUND 2
Descriptor: 2-{[(trans-4-methylcyclohexyl)carbonyl](propan-2-yl)amino}-5-[2-(trifluoromethyl)phenoxy]benzoic acid, Genome polyprotein, MAGNESIUM ION
Authors:Coulombe, R.
Deposit date:2013-03-08
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype.
Bioorg.Med.Chem.Lett., 23, 2013
4JJU
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BU of 4jju by Molmil
Crystal structure of HCV NS5B polymerase in complex with COMPOUND 29
Descriptor: 1-(2,4-difluorobenzyl)-6-{[3-(trifluoromethyl)pyridin-2-yl]oxy}quinazolin-4(1H)-one, GLYCEROL, Genome polyprotein, ...
Authors:Coulombe, R.
Deposit date:2013-03-08
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype.
Bioorg.Med.Chem.Lett., 23, 2013

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건을2024-07-10부터공개중

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