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2GXQ
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BU of 2gxq by Molmil
HERA N-terminal domain in complex with AMP, crystal form 1
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, heat resistant RNA dependent ATPase
著者Rudolph, M.G, Klostermeier, D.
登録日2006-05-09
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006
2OXC
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BU of 2oxc by Molmil
Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Probable ATP-dependent RNA helicase DDX20
著者Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-02-20
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Human DEAD-box RNA helicase DDX20
To be Published
5ZBZ
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BU of 5zbz by Molmil
Crystal structure of the DEAD domain of Human eIF4A with sanguinarine
分子名称: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Eukaryotic initiation factor 4A-I, MALONATE ION
著者Ding, Y, Ding, L.
登録日2018-02-14
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.30860257 Å)
主引用文献Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling.
Cell Chem Biol, 26, 2019
3MWJ
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BU of 3mwj by Molmil
Q28E mutant of HERA N-terminal RecA-like domain, apo form
分子名称: Heat resistant RNA dependent ATPase, SULFATE ION
著者Rudolph, M.G, Klostermeier, D.
登録日2010-05-06
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3BER
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BU of 3ber by Molmil
Human DEAD-box RNA-helicase DDX47, conserved domain I in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Probable ATP-dependent RNA helicase DDX47, ...
著者Karlberg, T, Busam, R.D, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-11-20
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
3PEY
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BU of 3pey by Molmil
S. cerevisiae Dbp5 bound to RNA and ADP BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3MWK
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BU of 3mwk by Molmil
Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP
分子名称: Heat resistant RNA dependent ATPase, SULFATE ION, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
著者Rudolph, M.G, Klostermeier, D.
登録日2010-05-06
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
6AIB
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BU of 6aib by Molmil
Crystal structures of the N-terminal RecA-like domain 1 of Staphylococcus aureus DEAD-box Cold shock RNA helicase CshA
分子名称: DEAD-box ATP-dependent RNA helicase CshA
著者Chengliang, W, Tian, T, Xiaobao, C, Xuan, Z, Jianye, Z.
登録日2018-08-22
公開日2018-11-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of the N-terminal domain of the Staphylococcus aureus DEAD-box RNA helicase CshA and its complex with AMP
Acta Crystallogr F Struct Biol Commun, 74, 2018
5GVR
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BU of 5gvr by Molmil
Crystal structure of the DDX41 DEAD domain in an apo closed form
分子名称: (2S)-2-hydroxybutanedioic acid, Probable ATP-dependent RNA helicase DDX41
著者Omura, H, Oikawa, D, Nakane, T, Kato, M, Ishii, R, Goto, Y, Suga, H, Ishitani, R, Tokunaga, F, Nureki, O.
登録日2016-09-06
公開日2016-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide
Sci Rep, 6, 2016
3PEW
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BU of 3pew by Molmil
S. cerevisiae Dbp5 L327V bound to RNA and ADP BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
7AUC
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BU of 7auc by Molmil
Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Chen, X, Oliver, A.W.
登録日2020-11-02
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
8DPE
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BU of 8dpe by Molmil
Crystal structure of ATP-dependent RNA helicase DDX42
分子名称: ATP-dependent RNA helicase DDX42
著者Larsen, N.A, Tsai, J.
登録日2022-07-15
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.531 Å)
主引用文献Crystal structure of ATP-dependent RNA helicase DDX42
To Be Published
7GQU
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BU of 7gqu by Molmil
Crystal Structure of Werner helicase fragment 517-945 in covalent complex with N-[(E,1S)-1-cyclopropyl-3-methylsulfonylprop-2-enyl]-2-(1,1-difluoroethyl)-4-phenoxypyrimidine-5-carboxamide
分子名称: ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, GLYCEROL, ...
著者Classen, M, Benz, J, Brugger, D, Tagliente, O, Rudolph, M.G.
登録日2023-10-19
公開日2024-05-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024
7GQS
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BU of 7gqs by Molmil
Crystal Structure of Werner helicase fragment 517-945 in complex with ADP
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, ...
著者Classen, M, Benz, J, Brugger, D, Rudolph, M.G.
登録日2023-10-19
公開日2024-05-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024
6UV3
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BU of 6uv3 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo2
分子名称: 125a-oligo2, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Ngo, T.D, Partin, A.C, Nam, Y.
登録日2019-11-01
公開日2020-01-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
5GJU
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BU of 5gju by Molmil
DEAD-box RNA helicase
分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD
著者Xu, L, Li, F, Wang, L, Shi, Y.
登録日2016-07-02
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
8PFP
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BU of 8pfp by Molmil
Crystal structure of WRN helicase domain in complex with ATPgammaS
分子名称: Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ZINC ION
著者Scheufler, C, Villard, F.
登録日2023-06-16
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers.
Nature, 629, 2024
3MWL
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BU of 3mwl by Molmil
Q28E mutant of HERA N-terminal RecA-like domain in complex with 8-OXOADENOSINE
分子名称: 6-azanyl-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one, Heat resistant RNA dependent ATPase, SULFATE ION
著者Rudolph, M.G, Klostermeier, D.
登録日2010-05-06
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
2GXS
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BU of 2gxs by Molmil
HERA N-terminal domain in complex with AMP, crystal form 2
分子名称: ADENOSINE MONOPHOSPHATE, CALCIUM ION, GLYCEROL, ...
著者Rudolph, M.G, Klostermeier, D.
登録日2006-05-09
公開日2006-08-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006
2GXU
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BU of 2gxu by Molmil
HERA N-terminal domain in complex with orthophosphate, crystal form 1
分子名称: PHOSPHATE ION, heat resistant RNA dependent ATPase
著者Rudolph, M.G, Klostermeier, D.
登録日2006-05-09
公開日2006-08-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006
6UV4
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BU of 6uv4 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-18a-oligo1
分子名称: 18a_oligo1, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Ngo, T.D, Partin, A.C, Nam, Y.
登録日2019-11-01
公開日2020-01-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
5LTJ
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BU of 5ltj by Molmil
Crystal structure of the Prp43-ADP-BeF3 complex (in orthorhombic space group)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Tauchert, M.J, Ficner, R.
登録日2016-09-06
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
6AIC
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BU of 6aic by Molmil
Crystal structures of the N-terminal domain of Staphylococcus aureus DEAD-box Cold shock RNA helicase CshA in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, DEAD-box ATP-dependent RNA helicase CshA
著者Tian, T, Chengliang, W, Xiaobao, C, Xuan, Z, Jianye, Z.
登録日2018-08-22
公開日2018-11-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of the N-terminal domain of the Staphylococcus aureus DEAD-box RNA helicase CshA and its complex with AMP
Acta Crystallogr F Struct Biol Commun, 74, 2018
1OYW
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BU of 1oyw by Molmil
Structure of the RecQ Catalytic Core
分子名称: ATP-dependent DNA helicase, MANGANESE (II) ION, ZINC ION
著者Bernstein, D.A, Zittel, M.C, Keck, J.L.
登録日2003-04-07
公開日2003-10-07
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution structure of the E. coli RecQ helicase catalytic core
Embo J., 22, 2003
6L5O
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BU of 6l5o by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
登録日2019-10-24
公開日2020-06-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020

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件を2024-09-25に公開中

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