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6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2018-12-10
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2018-12-06
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2018-12-07
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
4OWR
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BU of 4owr by Molmil
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair Rae1-Nup98
分子名称: Matrix protein, Nuclear pore complex protein Nup98-Nup96, mRNA export factor
著者Ren, Y, Quan, B, Seo, H.S, Blobel, G.
登録日2014-02-03
公開日2014-06-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 Nup98).
Proc.Natl.Acad.Sci.USA, 111, 2014
2B7E
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BU of 2b7e by Molmil
First FF domain of Prp40 Yeast Protein
分子名称: Pre-mRNA processing protein PRP40
著者Gasch, A, Wiesner, S, Martin-Malpartida, P, Ramirez-Espain, X, Ruiz, L, Macias, M.J.
登録日2005-10-04
公開日2005-11-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.
J.Biol.Chem., 281, 2006
8C43
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BU of 8c43 by Molmil
Ternary structure of 14-3-3sigma, strep-tagged PKA-responsive ERa phosphopeptide, and Fusicoccin-A.
分子名称: 14-3-3 protein sigma, De-acetylated Fusicoccin, Estrogen Receptor alpha phosphopeptide, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-12-30
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis and dual ligand regulation of tetrameric estrogen receptor alpha /14-3-3 zeta protein complex.
J.Biol.Chem., 299, 2023
8C42
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BU of 8c42 by Molmil
Ternary structure of 14-3-3sigma, PKA-responsive ERa phosphopeptide and Fusicoccin-A
分子名称: 14-3-3 protein sigma, De-acetylated Fusicoccin, Estrogen receptor, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-12-30
公開日2023-12-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis and dual ligand regulation of tetrameric estrogen receptor alpha /14-3-3 zeta protein complex.
J.Biol.Chem., 299, 2023
2M57
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BU of 2m57 by Molmil
NMR solution structure of domain 5 from Azotobacter vinelandii Intron 5 at pH 7.8
分子名称: RNA_(35-MER)
著者Pechlaner, M, Donghi, D, Zelenay, V, Sigel, R.K.O.
登録日2013-02-15
公開日2014-02-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Acid-base equilibria near neutral pH in the catalytic triad and the bulge of domain 5 of a bacterial group II intron
To be Published
4C0H
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BU of 4c0h by Molmil
Extended interface between Pcf11p and Clp1p and structural basis for ATP loss in Gly135Arg point mutant
分子名称: MRNA CLEAVAGE AND POLYADENYLATION FACTOR CLP1, PCF11P
著者Dupin, A.F, Fribourg, S.
登録日2013-08-02
公開日2014-02-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for ATP loss by Clp1p in a G135R mutant protein.
Biochimie, 101, 2014
1O6W
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BU of 1o6w by Molmil
Solution Structure of the Prp40 WW Domain Pair of the Yeast Splicing Factor Prp40
分子名称: PRE-MRNA PROCESSING PROTEIN PRP40
著者Wiesner, S, Stier, G, Sattler, M, Macias, M.J.
登録日2002-10-16
公開日2002-12-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure and Ligand Recognition of the Ww Domain Pair of the Yeast Splicing Factor Prp40
J.Mol.Biol., 324, 2002
4I2E
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BU of 4i2e by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(*AP*AP*AP*AP*A)-3', COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2C
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BU of 4i2c by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
8B5P
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BU of 8b5p by Molmil
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 10
分子名称: 14-3-3 protein sigma, 3-bromanyl-5-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-09-23
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
8B4Q
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BU of 8b4q by Molmil
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 5
分子名称: 14-3-3 protein sigma, 3-fluoranyl-4-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-09-20
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
8B2I
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BU of 8b2i by Molmil
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 4
分子名称: 14-3-3 protein sigma, 4-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-09-14
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
8B2K
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BU of 8b2k by Molmil
Ternary structure of 14-3-3s, RND3 phosphopeptide and dual-reactive compound 10
分子名称: 14-3-3 protein sigma, 3-bromanyl-5-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-09-14
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
8BJG
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BU of 8bjg by Molmil
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 8
分子名称: 14-3-3 protein sigma, 3-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-11-04
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
8BJN
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BU of 8bjn by Molmil
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 6
分子名称: 14-3-3 protein sigma, 3-bromanyl-4-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-11-04
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
8BM5
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BU of 8bm5 by Molmil
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 7
分子名称: 14-3-3 protein sigma, 4-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzenesulfonamide, CHLORIDE ION, ...
著者Somsen, B.A, Ottmann, C.
登録日2022-11-10
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
3FM7
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BU of 3fm7 by Molmil
Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain
分子名称: Dynein intermediate chain, cytosolic, Dynein light chain 1, ...
著者Hall, J.D, Karplus, P.A, Barbar, E.J.
登録日2008-12-19
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Multivalency in the assembly of intrinsically disordered Dynein intermediate chain.
J.Biol.Chem., 284, 2009
3GLW
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BU of 3glw by Molmil
Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain
分子名称: Dynein intermediate Chain, Dynein light chain 1, cytoplasmic
著者Hall, J.D, Karplus, P.A, Barbar, E.J.
登録日2009-03-12
公開日2009-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Multivalency in the assembly of intrinsically disordered Dynein intermediate chain.
J.Biol.Chem., 284, 2009
1H6K
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BU of 1h6k by Molmil
nuclear Cap Binding Complex
分子名称: 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80
著者Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S.
登録日2001-06-18
公開日2001-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Human Nuclear CAP Binding Complex
Mol.Cell, 8, 2001
6FF4
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BU of 6ff4 by Molmil
human Bact spliceosome core structure
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
登録日2018-01-03
公開日2018-08-29
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
9FA4
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BU of 9fa4 by Molmil
Structure of the Integrator arm module containing subunits INTS10/13/14/15 (state 1)
分子名称: Integrator complex subunit 10, Integrator complex subunit 13, Integrator complex subunit 14, ...
著者Razew, M, Galej, W.P.
登録日2024-05-10
公開日2024-06-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of the Integrator complex assembly and association with transcription factors.
Mol.Cell, 84, 2024
9FA7
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BU of 9fa7 by Molmil
Structure of the Integrator arm module containing subunits INTS10/13/14/15 (state 3)
分子名称: Integrator complex subunit 10, Integrator complex subunit 13, Integrator complex subunit 14, ...
著者Razew, M, Galej, W.P.
登録日2024-05-10
公開日2024-06-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of the Integrator complex assembly and association with transcription factors.
Mol.Cell, 84, 2024

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