8WPF
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | 著者 | Wang, X, Li, N, Gao, N. | 登録日 | 2023-10-10 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8WPK
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | 著者 | Wang, X, Li, N, Gao, N. | 登録日 | 2023-10-10 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8WPP
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA | 分子名称: | A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ... | 著者 | Wang, X, Li, N, Gao, N. | 登録日 | 2023-10-10 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8V6J
| DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | 著者 | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-12-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (11.11 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V5N
| Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Mullins, E.A, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-11-30 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (8.56 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V5O
| Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Mullins, E.A, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-11-30 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (8.99 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V6G
| DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | 著者 | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-12-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (11.16 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V5M
| Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Mullins, E.A, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-11-30 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (9.22 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V6H
| DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | 著者 | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-12-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (11.11 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V6I
| DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | 著者 | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-12-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (14.06 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
3L8B
| Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin | 分子名称: | DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), DNA polymerase, ... | 著者 | Aller, P, Ye, Y, Wallace, S.S, Burrows, C.J, Doublie, S. | 登録日 | 2009-12-30 | 公開日 | 2010-03-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Biochemistry, 49, 2010
|
|
3LDS
| Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*(8OG)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(DDG))-3'), ... | 著者 | Hogg, M, Midkiff, J, Rudnicki, J, Reha-Krantz, L, Doublie, S, Wallace, S.S. | 登録日 | 2010-01-13 | 公開日 | 2010-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Biochemistry, 49, 2010
|
|
3NAE
| RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-01 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
|
|
3LZJ
| RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine | 分子名称: | CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | 登録日 | 2010-03-01 | 公開日 | 2010-05-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Biochemistry, 49, 2010
|
|
3LZI
| RB69 DNA Polymerase (Y567A) ternary complex with dATP Opposite 7,8-dihydro-8-oxoguanine | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | 登録日 | 2010-03-01 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Biochemistry, 49, 2010
|
|
3MAQ
| Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | 著者 | Yang, W, Wang, F. | 登録日 | 2010-03-24 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
|
|
3NHG
| RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dTTP Opposite dG | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | 著者 | Wang, M, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-14 | 公開日 | 2011-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
|
|
3NCI
| RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J. | 登録日 | 2010-06-04 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex. Biochemistry, 50, 2011
|
|
3NE6
| RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dCTP Opposite dG | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-08 | 公開日 | 2011-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
|
|
3NGI
| RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite dG | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | 著者 | Wang, M, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-11 | 公開日 | 2011-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.886 Å) | 主引用文献 | Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
|
|
3NDK
| RB69 DNA Polymerase (Y567A) Ternary Complex with dCTP Opposite dG | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-07 | 公開日 | 2011-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
|
|
8J8G
| Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and cidofovir diphosphate | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*T)-3'), ... | 著者 | Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C. | 登録日 | 2023-05-01 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270, 2024
|
|
8J86
| Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*TP*)-3'), ... | 著者 | Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C. | 登録日 | 2023-04-30 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270, 2024
|
|
8J8F
| Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), ... | 著者 | Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C. | 登録日 | 2023-05-01 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270, 2024
|
|
8KG6
| Yeast replisome in state I | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | 登録日 | 2023-08-17 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
|
|