PDB: 304 件ウェブページステータス検索Chemie searchBIRD

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5W8L	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 59 and NADH 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-([1,1'-biphenyl]-3-yl)-5-(cyclopropylmethyl)-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, ... 著者 Davies, D.R, Dranow, D.M. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
2A94	Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH. 分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase 著者 Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. 登録日 2005-07-11 公開日 2006-01-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH. Biochemistry, 44, 2005
2E37	Structure of TT0471 protein from Thermus thermophilus 分子名称: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Lokanath, N.K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-11-21 公開日 2007-11-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of TT0471 protein from Thermus thermophilus To be Published
4UUN	Trichomonas vaginalis lactate dehydrogenase in complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4UUO	Apo Trichomonas vaginalis malate dehydrogenase 分子名称: CYTOSOLIC MALATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.842 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4WLF	Crystal structure of L-malate bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-malate bound MDH2 To Be Published
4WLN	Crystal structure of apo MDH2 分子名称: Malate dehydrogenase, mitochondrial, PHOSPHATE ION 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of apo MDH2 To Be Published
4WLE	Crystal structure of citrate bound MDH2 分子名称: CITRIC ACID, Malate dehydrogenase, mitochondrial 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of citrate bound MDH2 To Be Published
4WLV	Crystal structure of NAD bound MDH2 分子名称: Malate dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-08 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of NAD bound MDH2 To Be Published
2X0R	R207S, R292S Mutant of Malate Dehydrogenase from the Halophilic Archeon Haloarcula marismortui (HoloForm) 分子名称: CHLORIDE ION, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Irimia, A, Ebel, C, Vellieux, F.M.D, Richard, S.B, Cosenza, L.W, Zaccai, G, Madern, D. 登録日 2009-12-17 公開日 2009-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.915 Å) 主引用文献 The Oligomeric States of Haloarcula Marismortui Malate Dehydrogenase are Modulated by Solvent Components as Shown by Crystallographic and Biochemical Studies J.Mol.Biol., 326, 2003
4WLU	Crystal structure of L-malate and NAD bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-08 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal structure of L-malate and NAD bound MDH2 To Be Published
2X0I	2.9 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALATE DEHYDROGENASE, SODIUM ION, ... 著者 Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M.D, Karshikoff, A, Tibbelin, G, Ladenstein, R, Lien, T, Birkeland, N.-K. 登録日 2009-12-14 公開日 2009-12-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 The 2.9A Resolution Crystal Structure of Malate Dehydrogenase from Archaeoglobus Fulgidus: Mechanisms of Oligomerisation and Thermal Stabilisation. J.Mol.Biol., 335, 2004
4WLO	Crystal structure of oxaloacetate and NADH bound MDH2 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of oxaloacetate and NADH bound MDH2 To Be Published
2X8L	Plasmodium falciparum lactate dehydrogenase apo structure 分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE 著者 Birkinshaw, R.W, Brady, R.L. 登録日 2010-03-10 公開日 2010-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Apo Crystal Structure of Plasmodium Falciparum Lactate Dehydrogenase To be Published
2XXB	Penta-mutant of Thermus thermophilus lactate dehydrogenase, complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, L-LACTATE DEHYDROGENASE 著者 Diop, F, Coquelle, N, Vellieux, F.M.D. 登録日 2010-11-09 公開日 2010-11-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Lactate Dehydrogenase from T. Thermophilus, Penta-Mutant (Complex with AMP) To be Published
2XXJ	Penta mutant of lactate dehydrogenase from Thermus thermophilus, ternary complex 分子名称: L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... 著者 Tickle, J, de Mendoza Barbera, E, Vellieux, F.M.D. 登録日 2010-11-10 公開日 2010-11-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.964 Å) 主引用文献 Lactate Dehydrogenase from T. Thermophilus, Penta- Mutant (Ternary Complex) To be Published
2X0J	2.8 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH ETHENO-NAD 分子名称: ETHENO-NAD, MALATE DEHYDROGENASE, SULFATE ION 著者 Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M, Karshikoff, A, Tibbelin, G, Ladenstein, R, Lien, T, Birkeland, N.K. 登録日 2009-12-14 公開日 2009-12-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.786 Å) 主引用文献 The 2.9A Resolution Crystal Structure of Malate Dehydrogenase from Archaeoglobus Fulgidus: Mechanisms of Oligomerisation and Thermal Stabilisation. J.Mol.Biol., 335, 2004
2ZQY	T-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei 分子名称: L-lactate dehydrogenase, NITRATE ION 著者 Arai, K, Ishimitsu, T, Fushinobu, S, Uchikoba, H, Matsuzawa, H, Taguchi, H. 登録日 2008-08-22 公開日 2009-09-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase. Proteins, 78, 2010
2ZQZ	R-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei 分子名称: L-lactate dehydrogenase, SULFATE ION 著者 Arai, K, Ishimitsu, T, Fushinobu, S, Uchikoba, H, Matsuzawa, H, Taguchi, H. 登録日 2008-08-22 公開日 2009-09-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase. Proteins, 78, 2010
1WZE	Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. 登録日 2005-03-04 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for alteration of cofactor specificity of malate dehydrogenase from Thermus flavus to be published
1WZI	Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus 分子名称: Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. 登録日 2005-03-05 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for alteration of cofactor specificity of malate dehydrogenase from Thermus flavus to be published
1XIV	Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol 分子名称: 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL, L-lactate dehydrogenase 著者 Conners, R, Cameron, A, Read, J.A, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-09-22 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase MOL.BIOCHEM.PARASITOL., 142, 2005
1Y6J	L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135 分子名称: L-lactate dehydrogenase 著者 Chen, L, Yang, H, Kataeva, I, Chen, L.R, Tempel, W, Lee, D, Habel, J, Zhou, W, Lin, D, Ljungdahl, L, Liu, Z.-J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) 登録日 2004-12-06 公開日 2004-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135 To be Published
1UXI	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: FUMARIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
1UXH	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: FUMARIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004

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