PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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6W92	Human UHRF1 TTD domain 分子名称: E3 ubiquitin-protein ligase UHRF1 著者 Campbell, J.C, Chang, L, Sankaran, B, Young, D.W. 登録日 2020-03-21 公開日 2021-02-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Sci Rep, 11, 2021
3NC1	Crystal structure of the CRM1-RanGTP complex 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. 登録日 2010-06-04 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
3NGH	Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1 分子名称: PDZ domain-containing protein 1 著者 Kocher, O, Birrane, G, Krieger, M, Ladias, J.A. 登録日 2010-06-11 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1. J.Biol.Chem., 285, 2010
3NH7	Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA 分子名称: Antibody fragment Fab AbD1556, heavy chain, light chain, ... 著者 Mueller, T.D, Harth, S, Sebald, W. 登録日 2010-06-14 公開日 2010-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity Plos One, 5, 2010
8B3S	Structure of YjbA in complex with ClpC N-terminal Domain 分子名称: ATP-dependent Clp protease ATP-binding subunit ClpC / Negative regulator of tic competence clcC/mecB, GLYCEROL, MAGNESIUM ION, ... 著者 Evans, N.J, Isaacson, R.L, Camp, A.H, Collins, M.K. 登録日 2022-09-16 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure of YjbA in complex with ClpC N-terminal Domain To Be Published
8AP5	Cadmium-loaded form of Caenorhabditis elegans MTL-2 分子名称: CADMIUM ION, Metallothionein-2 著者 Leszczyszyn, O.I, Sturzenbaum, S.R, Blindauer, C.A. 登録日 2022-08-09 公開日 2024-01-17 実験手法 SOLUTION NMR 主引用文献 Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins. Chemosphere, 350, 2023
8AQ9	Domain 2 of zinc-loaded Caenorhabditis elegans MTL-1 分子名称: Metallothionein-1, ZINC ION 著者 Leszczyszyn, O.I, Sturzenbaum, S.R, Blindauer, C.A. 登録日 2022-08-11 公開日 2024-01-17 実験手法 SOLUTION NMR 主引用文献 Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins. Chemosphere, 350, 2023
6WJA	UDP-GlcNAc C4-epimerase mutant S121A/Y146F from Pseudomonas protegens in complex with UDP-GalNAc 分子名称: NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE 著者 Marmont, L.S, Pfoh, R, Howell, P.L. 登録日 2020-04-13 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.094 Å) 主引用文献 PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation. J.Biol.Chem., 295, 2020
3OWS	Crystal Structure of Ketosteroid Isomerase D40N/C69S/C81S/C97S/M116C-CN from P. putida with Bound Equilenin 分子名称: EQUILENIN, Steroid Delta-isomerase 著者 Sigala, P.A, Fenn, T.D, Herschlag, D. 登録日 2010-09-20 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site. Proc.Natl.Acad.Sci.USA, 109, 2013
4J99	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Gain-of-Function K659T Mutation. 分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Chen, H, Mohammadi, M. 登録日 2013-02-15 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8474 Å) 主引用文献 Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep, 4, 2013
8SMW	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 1) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
3P4K	The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution 分子名称: MAP kinase 14, Mitogen-activated protein kinase 14 著者 Akella, R, Min, X, Wu, Q, Gardner, K.H, Goldsmith, E.J. 登録日 2010-10-06 公開日 2011-01-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution Structure, 18, 2010
8SN7	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 5) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMX	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 2) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN6	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 4) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
6WTJ	Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication 分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase 著者 Khan, M.B, Arutyunova, E, Young, H.S, Lemieux, M.J. 登録日 2020-05-02 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun, 11, 2020
8SN4	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 2) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMY	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 3) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
3P7J	Drosophila HP1a chromo shadow domain 分子名称: GLYCEROL, Heterochromatin protein 1 著者 Kim, D, Chruszcz, M, Minor, W, Khorasanizadeh, S. 登録日 2010-10-12 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners. Chembiochem, 12, 2011
8SN2	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) 分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. 登録日 2023-04-26 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
4J8O	SET7/9 in complex with TAF10K189A peptide and AdoHcy 分子名称: Histone-lysine N-methyltransferase SETD7, S-ADENOSYL-L-HOMOCYSTEINE, Transcription initiation factor TFIID subunit 10 著者 Horowitz, S, Trievel, R.C. 登録日 2013-02-14 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases. J.Am.Chem.Soc., 135, 2013
8R3D	Crystal structure of Pent only at pH 8.8 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Beta propeller 著者 Flood, R.J, Crowley, P.B. 登録日 2023-11-08 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Multivalent Calixarene Complexation of a Designed Pentameric Lectin. Biomacromolecules, 25, 2024
6WCY	N160D Deamidation Mutant of Human gammaD-Crystallin 分子名称: Gamma-crystallin D, SULFATE ION 著者 Whitley, M.J, Rathi, N, Ambarian, M, Gronenborn, A.M. 登録日 2020-03-31 公開日 2021-01-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.204 Å) 主引用文献 Assessing the Structures and Interactions of gamma D-Crystallin Deamidation Variants. Structure, 29, 2021
6VU0	CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ENZYME I OF THE BACTERIAL PHOSPHOTRANSFERASE SYSTEM FROM THE ESCHERICHIA COLI ENZYME 分子名称: PEP-protein phosphotransferase system enzyme I, SULFATE ION 著者 Stewart Jr, C.E. 登録日 2020-02-14 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Hybrid Thermophilic/Mesophilic Enzymes Reveal a Role for Conformational Disorder in Regulation of Bacterial Enzyme I. J.Mol.Biol., 432, 2020
8QXI	SipA solution structure 分子名称: Uncharacterized protein SEF0032 著者 Neira, J.L. 登録日 2023-10-24 公開日 2024-03-06 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of the cyanobacterial regulator SipA. Arch.Biochem.Biophys., 754, 2024

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