PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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3WIX	Crystal structure of Mcl-1 in complex with compound 4 分子名称: 7-(4-carboxyphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Sogabe, S, Igaki, S, Hayano, Y. 登録日 2013-09-26 公開日 2013-11-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
3WIY	Crystal structure of Mcl-1 in complex with compound 10 分子名称: 7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Sogabe, S, Igaki, S, Hayano, Y. 登録日 2013-09-26 公開日 2013-11-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
1P2F	Crystal Structure Analysis of Response Regulator DrrB, a Thermotoga maritima OmpR/PhoB Homolog 分子名称: Response Regulator 著者 Robinson, V.L, Wu, T, Stock, A.M. 登録日 2003-04-15 公開日 2003-04-29 最終更新日 2018-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural analysis of the domain interface in DrrB, a response regulator of the OmpR/PhoB subfamily J.Bacteriol., 185, 2003
1J9J	CRYSTAL STRUCTURE ANALYSIS OF SURE PROTEIN FROM T.MARITIMA 分子名称: MAGNESIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, SULFATE ION 著者 Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. 登録日 2001-05-27 公開日 2001-09-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family. Nat.Struct.Biol., 8, 2001
3WFF	Mineralocorticoid receptor ligand-binding domain with compound 2b 分子名称: 6-[4-(2,4-difluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor, PHOSPHATE ION 著者 Sogabe, S, Habuka, N. 登録日 2013-07-19 公開日 2013-08-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists. Bioorg.Med.Chem., 21, 2013
3W33	EGFR kinase domain complexed with compound 19b 分子名称: 4-{[4-(1-benzothiophen-4-yloxy)-3-chlorophenyl]amino}-N-(2-hydroxyethyl)-8,9-dihydro-7H-pyrimido[4,5-b]azepine-6-carboxamide, Epidermal growth factor receptor, SULFATE ION 著者 Sogabe, S, Kawakita, Y. 登録日 2012-12-07 公開日 2013-03-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors Bioorg.Med.Chem., 21, 2013
3W77	Crystal Structure of azoreductase AzrA 分子名称: FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 著者 Ogata, D, Yu, J, Ooi, T, Yao, M. 登録日 2013-02-27 公開日 2014-02-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
3WFG	Mineralocorticoid receptor ligand-binding domain with compuond 2e 分子名称: 1,2-ETHANEDIOL, 6-[(2S)-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor 著者 Sogabe, S, Habuka, N. 登録日 2013-07-19 公開日 2013-08-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists. Bioorg.Med.Chem., 21, 2013
3WIZ	Crystal structure of Bcl-xL in complex with compound 10 分子名称: 7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Bcl-2-like protein 1, PHOSPHATE ION 著者 Sogabe, S, Igaki, S, Hayano, Y. 登録日 2013-09-26 公開日 2013-11-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
4A6T	Crystal structure of the omega transaminase from Chromobacterium violaceum in complex with PLP 分子名称: OMEGA TRANSAMINASE, PYRIDOXAL-5'-PHOSPHATE 著者 Logan, D.T, Hakansson, M, Yengo, K, Svedendahl Humble, M, Engelmark Cassimjee, K, Walse, B, Abedi, V, Federsel, H.-J, Berglund, P. 登録日 2011-11-08 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of the Chromobacterium Violaceum Omega-Transaminase Reveal Major Structural Rearrangements Upon Binding of Coenzyme Plp. FEBS J., 279, 2012
4A6U	Crystal structure of the omega transaminase from Chromobacterium violaceum in the apo form, crystallised from PEG 3350 分子名称: OMEGA TRANSAMINASE, SODIUM ION, THIOCYANATE ION 著者 Logan, D.T, Hakansson, M, Yengo, K, Svedendahl Humble, M, Engelmark Cassimjee, K, Walse, B, Abedi, V, Federsel, H.-J, Berglund, P. 登録日 2011-11-08 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.687 Å) 主引用文献 Crystal Structures of the Chromobacterium Violaceum Omega-Transaminase Reveal Major Structural Rearrangements Upon Binding of Coenzyme Plp. FEBS J., 279, 2012
4A72	Crystal structure of the omega transaminase from Chromobacterium violaceum in a mixture of apo and PLP-bound states 分子名称: OMEGA TRANSAMINASE, PYRIDOXAL-5'-PHOSPHATE 著者 Logan, D.T, Hakansson, M, Yengo, K, Svedendahl Humble, M, Engelmark Cassimjee, K, Walse, B, Abedi, V, Federsel, H.-J, Berglund, P. 登録日 2011-11-10 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structures of the Chromobacterium Violaceum Omega-Transaminase Reveal Major Structural Rearrangements Upon Binding of Coenzyme Plp. FEBS J., 279, 2012
1LBM	CRYSTAL STRUCTURE OF PHOSPHORIBOSYL ANTHRANILATE ISOMERASE (PRAI) IN COMPLEX WITH REDUCED 1-(O-CARBOXYPHENYLAMINO)-1-DEOXYRIBULOSE 5-PHOSPHATE (RCDRP) 分子名称: 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, PHOSPHORIBOSYL ANTHRANILATE ISOMERASE 著者 Hennig, M, Sterner, R, Kirschner, K. 登録日 2002-04-04 公開日 2002-12-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates Biochemistry, 41, 2002
4A6R	Crystal structure of the omega transaminase from Chromobacterium violaceum in the apo form, crystallised from polyacrylic acid 分子名称: OMEGA TRANSAMINASE, POLYACRYLIC ACID 著者 Logan, D.T, Hakansson, M, Yengo, K, Svedendahl Humble, M, Engelmark Cassimjee, K, Walse, B, Abedi, V, Federsel, H.-J, Berglund, P. 登録日 2011-11-08 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.349 Å) 主引用文献 Crystal Structures of the Chromobacterium Violaceum Omega-Transaminase Reveal Major Structural Rearrangements Upon Binding of Coenzyme Plp. FEBS J., 279, 2012
1INL	Crystal Structure of Spermidine Synthase from Thermotoga Maritima 分子名称: Spermidine synthase 著者 Korolev, S, Skarina, T, Ikeguchi, Y, Pegg, A.E, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) 登録日 2001-05-14 公開日 2001-11-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor. Nat.Struct.Biol., 9, 2002
3SFT	Crystal structure of Thermotoga maritima CheB methylesterase catalytic domain 分子名称: Chemotaxis response regulator protein-glutamate methylesterase 著者 Park, S.Y, Crane, B.R. 登録日 2011-06-14 公開日 2011-07-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 An insight into the interaction mode between CheB and chemoreceptor from two crystal structures of CheB methylesterase catalytic domain Biochem.Biophys.Res.Commun., 411, 2011
2FGC	Crystal structure of Acetolactate synthase- small subunit from Thermotoga maritima 分子名称: MAGNESIUM ION, acetolactate synthase, small subunit 著者 Petkowski, J.J, Chruszcz, M, Zimmerman, M.D, Zheng, H, Cymborowski, M.T, Koclega, K.D, Kudritska, M, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2005-12-21 公開日 2006-02-07 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit. Protein Sci., 16, 2007
1J9L	CRYSTAL STRUCTURE OF SURE PROTEIN FROM T.MARITIMA IN COMPLEX WITH VANADATE 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, ... 著者 Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. 登録日 2001-05-28 公開日 2001-09-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family. Nat.Struct.Biol., 8, 2001
5OLQ	Rhamnogalacturonan lyase 分子名称: CALCIUM ION, PHOSPHATE ION, Rhamnogalacturonan lyase 著者 Basle, A, Luis, A.S, Gilbert, H.J. 登録日 2017-07-28 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol, 3, 2018
5OLR	Rhamnogalacturonan lyase 分子名称: CALCIUM ION, PHOSPHATE ION, Rhamnogalacturonan lyase, ... 著者 Basle, A, Luis, A.S, Gilbert, H.J. 登録日 2017-07-28 公開日 2017-11-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol, 3, 2018
1J9K	CRYSTAL STRUCTURE OF SURE PROTEIN FROM T.MARITIMA IN COMPLEX WITH TUNGSTATE 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, ... 著者 Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. 登録日 2001-05-27 公開日 2001-09-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family. Nat.Struct.Biol., 8, 2001
5OLS	Rhamnogalacturonan lyase 分子名称: 4-deoxy-beta-L-threo-hex-4-enopyranuronic acid-(1-2)-alpha-L-rhamnopyranose-(1-4)-beta-D-galactopyranuronic acid, CALCIUM ION, Rhamnogalacturonan lyase, ... 著者 Basle, A, Luis, A.S, Gilbert, H.J. 登録日 2017-07-28 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol, 3, 2018
3SXK	Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator 分子名称: BICARBONATE ION, SULFATE ION, Transcriptional regulator, ... 著者 Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) 登録日 2011-07-15 公開日 2011-11-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator To be Published
1OIF	Family 1 b-glucosidase from Thermotoga maritima 分子名称: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, BETA-GLUCOSIDASE 著者 Gloster, T, Zechel, D, Boraston, A.B, Boraston, C.M, Macdonald, J.M, Tilbrook, D.M, Stick, R.V, Davies, G.J. 登録日 2003-06-16 公開日 2003-11-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases J.Am.Chem.Soc., 125, 2003
1O2A	Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FAD at 1.8 A resolution 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX 著者 Mathews, I.I, Deacon, A.M, Canaves, J.M, McMullan, D, Lesley, S.A, Agarwalla, S, Kuhn, P, Joint Center for Structural Genomics (JCSG) 登録日 2003-02-18 公開日 2003-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein Structure, 11, 2003

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