PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

---

3SPF	Crystal Structure of Bcl-xL bound to BM501 分子名称: 4-(4-chlorophenyl)-1-[(3S)-3,4-dihydroxybutyl]-N-[3-(4-methylpiperazin-1-yl)propyl]-3-phenyl-1H-pyrrole-2-carboxamide, Bcl-2-like protein 1, GLYCEROL 著者 Meagher, J.L, Stuckey, J.A. 登録日 2011-07-01 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold. J.Med.Chem., 55, 2012
3SRV	Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor 分子名称: 2-{[(3R,4R)-3-aminotetrahydro-2H-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK 著者 Somers, D.O, Neu, M. 登録日 2011-07-07 公開日 2011-09-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
3SPR	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer FC-THF 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A-THF, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-07-03 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SS7	Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.55 A resolution 分子名称: D-serine dehydratase, GLYCEROL, POTASSIUM ION, ... 著者 Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D. 登録日 2011-07-07 公開日 2012-01-18 最終更新日 2012-02-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of D-serine dehydratase from Escherichia coli. Biochim.Biophys.Acta, 1824, 2011
3SSE	DNA binding domain of restriction endonuclease bound to DNA 分子名称: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*A*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*T*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3') 著者 Sukackaite, R, Grazulis, S, Siksnys, V. 登録日 2011-07-08 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine. Nucleic Acids Res., 40, 2012
3SSL	Engineered high-affinity halide-binding protein derived from YFP: iodide complex 分子名称: Green fluorescent protein, IODIDE ION 著者 Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W. 登録日 2011-07-08 公開日 2012-07-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.449 Å) 主引用文献 Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition To be published
3SQO	PCSK9 J16 Fab complex 分子名称: J16 Heavy chain, J16 Light chain, PCSK9 prodomain, ... 著者 Strop, P. 登録日 2011-07-05 公開日 2012-05-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates. J.Pharmacol.Exp.Ther., 340, 2012
3SSY	Engineered low-affinity halide-binding protein derived from YFP: iodide complex 分子名称: Green fluorescent protein, IODIDE ION 著者 Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W. 登録日 2011-07-08 公開日 2012-07-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.769 Å) 主引用文献 Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition To be Published
3STM	Structure of human LFABP in complex with one molecule of palmitic acid 分子名称: Fatty acid-binding protein, liver, PALMITIC ACID 著者 Sharma, A, Sharma, A. 登録日 2011-07-11 公開日 2011-08-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.216 Å) 主引用文献 Fatty acid induced remodeling within the Human liver fatty acid binding protein J.Biol.Chem., 2011
3STV	Crystal Structure of tomato Methylketone Synthase I complexed with 3-hydroxyoctanoate 分子名称: (3S)-3-hydroxyoctanoic acid, BROMIDE ION, Methylketone synthase 1 著者 Auldridge, M.E, Austin, M.B, Noel, J.P. 登録日 2011-07-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. Plant Cell, 24, 2012
3SSA	Crystal structure of subunit B mutant N157T of the A1AO ATP synthase 分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Sundararaman, L, Manimekalai, M.S.S, Jeyakanthan, J, Gruber, G. 登録日 2011-07-08 公開日 2012-09-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of subunit A mutants H156A, N157A and N157T of the A1AO ATP synthase To be Published
3SSX	E. coli trp aporeporessor L75F mutant 分子名称: TRIS(HYDROXYETHYL)AMINOMETHANE, Trp operon repressor 著者 Benoff, B, Carey, J, Berman, H.M, Lawson, C.L. 登録日 2011-07-08 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5801 Å) 主引用文献 Environment-dependent long-range structural distortion in a temperature-sensitive point mutant. Protein Sci., 21, 2012
3SV9	Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir 分子名称: (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, GLYCEROL, NS3 protease, ... 著者 Schiffer, C.A, Romano, K.P. 登録日 2011-07-12 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
3SY0	S25-2- A(2-8)-A(2-4)KDO trisaccharide complex 分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, MAGNESIUM ION, S25-2 FAB (IGG1K) heavy chain, ... 著者 Nguyen, H.P, Seto, N.O, Mackenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V. 登録日 2011-07-15 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.489 Å) 主引用文献 Germline antibody recognition of distinct carbohydrate epitopes NAT.STRUCT.BIOL., 10, 2003
3SYK	Crystal structure of the AAA+ protein CbbX, selenomethionine structure 分子名称: Protein CbbX, SULFATE ION 著者 Mueller-Cajar, O, Stotz, M, Wendler, P, Hartl, F.U, Bracher, A, Hayer-Hartl, M. 登録日 2011-07-18 公開日 2011-11-09 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Structure and function of the AAA+ protein CbbX, a red-type Rubisco activase. Nature, 479, 2011
3SXC	Crystal structure of BBBB+UDP+Gal with Glycerol as the cryoprotectant 分子名称: DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... 著者 Johal, A.R, Evans, S.V. 登録日 2011-07-14 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
3SXK	Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator 分子名称: BICARBONATE ION, SULFATE ION, Transcriptional regulator, ... 著者 Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) 登録日 2011-07-15 公開日 2011-11-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator To be Published
3SZ3	Crystal structure of Tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan 分子名称: GLYCEROL, TRYPTOPHAN, Tryptophanyl-tRNA synthetase 著者 Cooper, D.R, Kudritska, M, Chruszcz, M, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-07-18 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan To be Published
3T0P	Crystal structure of a Putative DNA polymerase III beta subunit (EUBREC_0002; ERE_29750) from Eubacterium rectale ATCC 33656 at 2.26 A resolution 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-07-20 公開日 2011-08-10 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Crystal structure of a Putative DNA polymerase III beta subunit (EUBREC_0002; ERE_29750) from Eubacterium rectale ATCC 33656 at 2.26 A resolution To be published
3SZZ	Crystal Structure of Phosphonoacetate hydrolase from Sinorhizobium meliloti 1021 in complex with Acetate 分子名称: ACETATE ION, ZINC ION, phosphonoacetate hydrolase 著者 Agarwal, V, Nair, S.K. 登録日 2011-07-19 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and mechanistic insights into C-p bond hydrolysis by phosphonoacetate hydrolase. Chem.Biol., 18, 2011
3T1D	The mutant structure of human Siderocalin W79A, R81A, Y106F bound to Enterobactin 分子名称: 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-07-21 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands. J Struct Biol X, 2, 2019
3T0T	Crystal structure of S. aureus Pyruvate Kinase 分子名称: N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION, Pyruvate kinase 著者 Worrall, L.J, Vuckovic, M, Strynadka, N.C.J. 登録日 2011-07-20 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase. Acs Chem.Biol., 7, 2012
3T29	TMAO-grown trigonal trypsin (bovine) 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Cahn, J, Venkat, M, Marshall, H, Juers, D. 登録日 2011-07-22 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
3T2J	Tetragonal thermolysin in the presence of betaine 分子名称: CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Cahn, J, Hti Lar Seng, N.S, Juers, D. 登録日 2011-07-22 公開日 2011-12-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
3T48	Crystal Structure of truncated form of Staphylococcal Complement Inhibitor D (SCIN-D) at 1.5 Angstrom 分子名称: SCIN-D 著者 Garcia, B.L, Geisbrecht, B.V, Summers, B.J. 登録日 2011-07-25 公開日 2011-11-23 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family. J.Biol.Chem., 287, 2012

<589590591592593594595596597598599600601602603604>