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3V3J
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Kinetic and structural studies of thermostabilized mutants of HCA II.
分子名称: Carbonic anhydrase 2, ZINC ION
著者Boone, C.D, Fisher, S.Z, McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
3V2J
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Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION
著者Aggarwal, M, McKenna, A.
登録日2011-12-12
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II
To be Published
3V3F
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Kinetic and structural studies of thermostabilized mutants of HCA II.
分子名称: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION
著者Boone, C.D, Fisher, S.Z, McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
4E2O
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BU of 4e2o by Molmil
Crystal structure of alpha-amylase from Geobacillus thermoleovorans, GTA, complexed with acarbose
分子名称: 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha-amylase, CALCIUM ION, ...
著者Mok, S.C, Teh, A.H, Saito, J.A, Najimudin, N, Alam, M.
登録日2012-03-09
公開日2013-03-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Crystal structure of a compact alpha-amylase from Geobacillus thermoleovorans.
Enzyme.Microb.Technol., 53, 2013
4DO9
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Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: stereoselective binding of r-isomer
分子名称: 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, C C G A C C G C G C A T C A G C, CHLORIDE ION, ...
著者Batra, V.K.
登録日2012-02-09
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases
J.Am.Chem.Soc., 134, 2012
1OHG
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STRUCTURE OF THE DSDNA BACTERIOPHAGE HK97 MATURE EMPTY CAPSID
分子名称: CHLORIDE ION, MAJOR CAPSID PROTEIN, SULFATE ION
著者Helgstrand, C, Wikoff, W.R, Duda, R.L, Hendrix, R.W, Johnson, J.E, Liljas, L.
登録日2003-05-26
公開日2003-12-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献The Refined Structure of a Protein Catenane: The Hk97 Bacteriophage Capsid at 3.44A Resolution
J.Mol.Biol., 334, 2003
2FRZ
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Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F/V247L/C334A)
分子名称: Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Rao, Z, Wong, L.L, Xu, F, Bell, S.G.
登録日2006-01-20
公開日2007-01-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pentachlorobenzene oxidation by engineered cytochrome P450cam: Substrate binding and the mechanism of aromatic C-H bond oxidation
To be Published
4E2F
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Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state
分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION
著者Guo, W, Kantrowitz, E.R.
登録日2012-03-08
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DY9
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Leishmania major Peroxidase is a Cytochrome c Peroxidase
分子名称: Cytochrome c, PROTOPORPHYRIN IX CONTAINING FE
著者Jasion, V.S, Poulos, T.L.
登録日2012-02-28
公開日2012-03-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.082 Å)
主引用文献Leishmania major Peroxidase Is a Cytochrome c Peroxidase.
Biochemistry, 51, 2012
5TH3
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Restriction/modification system-Type II R.SwaI cleaved DNA complex
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (cleaved 25-MER, ...
著者Shen, B.W, Stoddard, B.L.
登録日2016-09-29
公開日2016-12-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
5TJK
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Crystal structure of GTA + A trisaccharide (native)
分子名称: GLYCEROL, Histo-blood group ABO system transferase, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside
著者Legg, M.S.G, Gagnon, S.M.L, Evans, S.V.
登録日2016-10-04
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release.
Glycobiology, 27, 2017
5QBW
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BU of 5qbw by Molmil
Crystal structure of human Cathepsin-S with bound ligand
分子名称: Cathepsin S, N-{[2-chloro-5-(2-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-3-oxo-2,3-dihydropyridazin-4-yl)phenyl]methyl}-4-fluorobenzamide
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QCJ
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Crystal structure of human Cathepsin-S with bound ligand
分子名称: 5-hydroxy-3-{1-[(2S)-2-hydroxy-3-{5-(methylsulfonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl]piperidin-4-yl}-1H-pyrrolo[3,2-c]pyridin-5-ium, Cathepsin S, SULFATE ION
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QBZ
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Crystal structure of human Cathepsin-S with bound ligand
分子名称: Cathepsin S, N-{[2-chloro-5-(4-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-3-oxo-3,4-dihydropyrazin-2-yl)phenyl]methyl}-4-fluorobenzamide
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QC8
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Crystal structure of human Cathepsin-S with bound ligand
分子名称: Cathepsin S, N-benzyl-1-{3-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}methanamine
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QC0
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Crystal structure of human Cathepsin-S with bound ligand
分子名称: 2-(dimethylamino)-1-[4-(2-oxo-2-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-1-propyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethyl)piperidin-1-yl]ethan-1-one, Cathepsin S
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
4CA0
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Structural Basis for the microtubule binding of the human kinetochore Ska complex
分子名称: SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1
著者Abad, M, Medina, B, Santamaria, A, Zou, J, Plasberg-Hill, C, Madhumalar, A, Jayachandran, U, Redli, P.M, Rappsilber, J, Nigg, E.A, Jeyaprakash, A.A.
登録日2013-10-04
公開日2014-01-22
実験手法X-RAY DIFFRACTION (2.259 Å)
主引用文献Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
5UGW
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BU of 5ugw by Molmil
STRUCTURE OF THE HUMAN TELOMERASE THUMB DOMAIN
分子名称: GLUTATHIONE, Telomerase reverse transcriptase
著者Skordalakes, E, Hoffman, H.
登録日2017-01-10
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
J. Biol. Chem., 292, 2017
5O7K
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BU of 5o7k by Molmil
Crystal structure of a single chain monellin mutant (Y65R) pH 2.0
分子名称: Monellin chain B,Monellin chain A, SULFATE ION
著者Pica, A, Merlino, A.
登録日2017-06-09
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862, 2017
4ERN
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BU of 4ern by Molmil
Crystal structure of the C-terminal domain of human XPB/ERCC-3 excision repair protein at 1.80 A
分子名称: TFIIH basal transcription factor complex helicase XPB subunit
著者Hilario, E, Li, Y, Fan, L.
登録日2012-04-20
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the C-terminal half of human XPB helicase and the impact of the disease-causing mutation XP11BE.
Acta Crystallogr.,Sect.D, 69, 2013
5QCA
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Crystal structure of human Cathepsin-S with bound ligand
分子名称: 1-{4-[(2-chloro-5-{1-[3-(4-cyclopropylpiperazin-1-yl)propyl]-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}-N-[(4-chlorophenyl)methyl]methanamine, Cathepsin S, SULFATE ION
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QBX
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BU of 5qbx by Molmil
Crystal structure of human Cathepsin-S with bound ligand
分子名称: (2S)-1-[4-(2-methoxyphenyl)piperidin-1-yl]-3-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propan-2-ol, Cathepsin S
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QCE
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BU of 5qce by Molmil
Crystal structure of human Cathepsin-S with bound ligand
分子名称: Cathepsin S, N-benzyl-1-{2-chloro-5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}methanamine
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5NJ7
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BU of 5nj7 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and arsenoplatin-1
分子名称: Ribonuclease pancreatic, arsenoplatin-1
著者Ferraro, G, Merlino, A.
登録日2017-03-28
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Arsenoplatin-1 Is a Dual Pharmacophore Anticancer Agent.
J.Am.Chem.Soc., 141, 2019
8OHD
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60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R.
登録日2023-03-21
公開日2024-02-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024

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件を2024-08-21に公開中

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