4F8H
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![BU of 4f8h by Molmil](/molmil-images/mine/4f8h) | X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel | 分子名称: | (R)-ketamine, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Proton-gated ion channel, ... | 著者 | Pan, J.J, Chen, Q, Willenbring, D, Kong, X.P, Cohen, A, Xu, Y, Tang, P. | 登録日 | 2012-05-17 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine. Structure, 20, 2012
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7LHE
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![BU of 7lhe by Molmil](/molmil-images/mine/7lhe) | Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION | 著者 | Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. | 登録日 | 2021-01-22 | 公開日 | 2021-06-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of type 1 IP3R channel in a lipid bilayer Commun Biol, 4, 2021
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7LHF
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![BU of 7lhf by Molmil](/molmil-images/mine/7lhf) | Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION | 著者 | Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. | 登録日 | 2021-01-22 | 公開日 | 2021-06-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Cryo-EM structure of type 1 IP3R channel in a lipid bilayer Commun Biol, 4, 2021
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3P50
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![BU of 3p50 by Molmil](/molmil-images/mine/3p50) | Structure of propofol bound to a pentameric ligand-gated ion channel, GLIC | 分子名称: | 2,6-BIS(1-METHYLETHYL)PHENOL, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. | 登録日 | 2010-10-07 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel Nature, 469, 2011
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3P4W
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![BU of 3p4w by Molmil](/molmil-images/mine/3p4w) | Structure of desflurane bound to a pentameric ligand-gated ion channel, GLIC | 分子名称: | (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. | 登録日 | 2010-10-07 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel Nature, 469, 2011
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7YP7
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![BU of 7yp7 by Molmil](/molmil-images/mine/7yp7) | apo-ADGRG2 coupled to Gs | 分子名称: | Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.M, Bu, R.Q, Xue, C.Y, Guo, S.C, Yuan, D.P, Xiao, P, Sun, J.P. | 登録日 | 2022-08-02 | 公開日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | apo-ADGRG2 coupled to Gs Nat.Chem.Biol., 2022
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7YDJ
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![BU of 7ydj by Molmil](/molmil-images/mine/7ydj) | Cryo EM structure of CD97/miniG12 complex | 分子名称: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Wang, N. | 登録日 | 2022-07-04 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Cryo EM structure of CD97/miniG12 complex To Be Published
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2YKS
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![BU of 2yks by Molmil](/molmil-images/mine/2yks) | |
1HAF
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![BU of 1haf by Molmil](/molmil-images/mine/1haf) | |
1HAE
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![BU of 1hae by Molmil](/molmil-images/mine/1hae) | |
1PZ8
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![BU of 1pz8 by Molmil](/molmil-images/mine/1pz8) | Modulation of agrin function by alternative splicing and Ca2+ binding | 分子名称: | Agrin, CALCIUM ION | 著者 | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | 登録日 | 2003-07-10 | 公開日 | 2004-04-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE, 12, 2004
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1PZ7
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![BU of 1pz7 by Molmil](/molmil-images/mine/1pz7) | Modulation of agrin function by alternative splicing and Ca2+ binding | 分子名称: | Agrin, CALCIUM ION | 著者 | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | 登録日 | 2003-07-10 | 公開日 | 2004-04-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.421 Å) | 主引用文献 | Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE, 12, 2004
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1Q56
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![BU of 1q56 by Molmil](/molmil-images/mine/1q56) | NMR structure of the B0 isoform of the agrin G3 domain in its Ca2+ bound state | 分子名称: | Agrin | 著者 | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | 登録日 | 2003-08-06 | 公開日 | 2004-04-13 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Modulation of agrin function by alternative splicing and Ca2+ binding Structure, 12, 2004
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1PZ9
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![BU of 1pz9 by Molmil](/molmil-images/mine/1pz9) | Modulation of agrin function by alternative splicing and Ca2+ binding | 分子名称: | Agrin | 著者 | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | 登録日 | 2003-07-10 | 公開日 | 2004-04-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE, 12, 2004
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2AOW
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![BU of 2aow by Molmil](/molmil-images/mine/2aow) | Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine | 分子名称: | Histamine N-methyltransferase, TACRINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | 登録日 | 2005-08-14 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs J.Mol.Biol., 353, 2005
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2AOX
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![BU of 2aox by Molmil](/molmil-images/mine/2aox) | Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine | 分子名称: | Histamine N-methyltransferase, TACRINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | 登録日 | 2005-08-14 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs J.Mol.Biol., 353, 2005
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6PNW
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![BU of 6pnw by Molmil](/molmil-images/mine/6pnw) | |
7SQ2
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![BU of 7sq2 by Molmil](/molmil-images/mine/7sq2) | Reprocessed and refined structure of Phospholipase C-beta and Gq signaling complex | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, ACETATE ION, CALCIUM ION, ... | 著者 | Endo-Streeter, S.T, Sondek, J, Harden, T.K. | 登録日 | 2021-11-04 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Kinetic Scaffolding Mediated by a Phospholipase C-{beta} and Gq Signaling Complex Science, 330, 2010
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1QKD
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1QKE
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![BU of 1qke by Molmil](/molmil-images/mine/1qke) | |
7SJL
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![BU of 7sjl by Molmil](/molmil-images/mine/7sjl) | |
8IU2
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![BU of 8iu2 by Molmil](/molmil-images/mine/8iu2) | Cryo-EM structure of Long-wave-sensitive opsin 1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Peng, Q, Cheng, X.Y, Li, J, Lu, Q.Y, Li, Y.Y, Zhang, J. | 登録日 | 2023-03-23 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structure of Long-wave-sensitive opsin 1 To Be Published
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6EBX
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![BU of 6ebx by Molmil](/molmil-images/mine/6ebx) | |
6CBV
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![BU of 6cbv by Molmil](/molmil-images/mine/6cbv) | Crystal structure of BRIL bound to an affinity matured synthetic antibody. | 分子名称: | BRIL, FORMIC ACID, GLYCEROL, ... | 著者 | Mukherjee, S, Skrobek, B, Kossiakoff, A.A. | 登録日 | 2018-02-05 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.872 Å) | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun, 11, 2020
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1ERA
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![BU of 1era by Molmil](/molmil-images/mine/1era) | |