PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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1PXI	HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-(2,5-Dichloro-thiophen-3-yl)-pyrimidin-2-ylamine 分子名称: 4-(2,5-DICHLOROTHIEN-3-YL)PYRIMIDIN-2-AMINE, Cell division protein kinase 2 著者 Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. 登録日 2003-07-04 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop Structure, 11, 2003
1PYI	CRYSTAL STRUCTURE OF A PPR1-DNA COMPLEX: DNA RECOGNITION BY PROTEINS CONTAINING A ZN2CYS6 BINUCLEAR CLUSTER 分子名称: DNA (5'-D(*TP*CP*GP*GP*CP*AP*AP*TP*TP*GP*CP*CP*GP*A)-3'), PROTEIN (PYRIMIDINE PATHWAY REGULATOR 1), ZINC ION 著者 Marmorstein, R, Harrison, S.C. 登録日 1995-01-04 公開日 1995-02-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster. Genes Dev., 8, 1994
1PW2	APO STRUCTURE OF HUMAN CYCLIN-DEPENDENT KINASE 2 分子名称: Cell division protein kinase 2 著者 Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. 登録日 2003-06-30 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop. Structure, 11, 2003
1PPF	X-RAY CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN LEUKOCYTE ELASTASE (PMN ELASTASE) AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR 分子名称: HUMAN LEUKOCYTE ELASTASE, TURKEY OVOMUCOID INHIBITOR (OMTKY3), alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Bode, W, Wei, A-Z. 登録日 1991-10-24 公開日 1994-01-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. EMBO J., 5, 1986
1Q4L	GSK-3 Beta complexed with Inhibitor I-5 分子名称: 2-CHLORO-5-[4-(3-CHLORO-PHENYL)-2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-3-YLAMINO]-BENZOIC ACID, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. 登録日 2003-08-04 公開日 2003-10-14 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors J.Mol.Biol., 333, 2003
2MSY	Solution structure of Hox homeodomain 分子名称: Homeobox protein Hox-C9 著者 Kim, H, Park, S, Han, J, Lee, B. 登録日 2014-08-11 公開日 2015-09-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding. Biochim.Biophys.Acta, 1854, 2015
4L85	Crystal structure of receiver domain of KdpE D52A mutant from E. coli 分子名称: IODIDE ION, KDP operon transcriptional regulatory protein KdpE 著者 Kumar, S, Yernool, D.A. 登録日 2013-06-15 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014
2N4T	NMR structure of Fbp28 WW domain L453W mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
2N4S	NMR structure of Fbp28 WW domain L453E mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
2N4W	NMR structure of Fbp28 WW domain T456Y mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
2MW9	NMR structure of FBP28 WW2 Y438R mutant 分子名称: Transcription elongation regulator 1 著者 Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. 登録日 2014-11-03 公開日 2014-12-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements. Proc.Natl.Acad.Sci.USA, 111, 2014
1R78	CDK2 complex with a 4-alkynyl oxindole inhibitor 分子名称: 4-((3R,4S,5R)-4-AMINO-3,5-DIHYDROXY-HEX-1-YNYL)-5-FLUORO-3-[1-(3-METHOXY-1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Cell division protein kinase 2 著者 Luk, K.-C, Simcox, M.E, Schutt, A, Rowan, K, Thompson, T, Chen, Y, Kammlott, U, DePinto, W, Dunten, P, Dermatakis, A. 登録日 2003-10-20 公開日 2004-01-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A new series of potent oxindole inhibitors of CDK2 Bioorg.Med.Chem.Lett., 14, 2004
1RML	NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES 分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, NAPHTHALENE TRISULFONATE 著者 Lozano, R.M, Jimenez, M.A, Santoro, J, Rico, M, Gimenez-Gallego, G. 登録日 1998-05-21 公開日 1998-11-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas. J.Mol.Biol., 281, 1998
4KNY	Crystal structure of the response regulator KdpE complexed to DNA in an active-like conformation 分子名称: KDP operon transcriptional regulatory protein KdpE, Promoter DNA 著者 Kumar, S, Narayanan, A, Yernool, D.A. 登録日 2013-05-10 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.945 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014
2N8G	NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens 分子名称: Homeobox protein GBX-1 著者 Proudfoot, A.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2015-10-15 公開日 2015-10-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens To be Published
2N4V	NMR structure of Fbp28 WW domain T456D mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
1PXJ	HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamine 分子名称: 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE, Cell division protein kinase 2 著者 Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. 登録日 2003-07-04 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop Structure, 11, 2003
1PYE	Crystal structure of CDK2 with inhibitor 分子名称: Cell division protein kinase 2, [2-AMINO-6-(2,6-DIFLUORO-BENZOYL)-IMIDAZO[1,2-A]PYRIDIN-3-YL]-PHENYL-METHANONE 著者 Zhang, F, Hamdouchi, C. 登録日 2003-07-08 公開日 2004-07-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines. MOL.CANCER THER., 3, 2004
2FPU	Crystal Structure of the N-terminal domain of E.coli HisB- Complex with histidinol 分子名称: CHLORIDE ION, Histidine biosynthesis bifunctional protein hisB, L-histidinol, ... 著者 Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2006-01-17 公開日 2006-09-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. J.Biol.Chem., 281, 2006
1PZZ	Crystal structure of FGF-1, V51N mutant 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Kim, J, Blaber, M. 登録日 2003-07-14 公開日 2004-07-27 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
2FPX	Crystal Structure of the N-terminal Domain of E.coli HisB- Sulfate complex. 分子名称: Histidine biosynthesis bifunctional protein hisB, MAGNESIUM ION, SULFATE ION, ... 著者 Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2006-01-17 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. J.Biol.Chem., 281, 2006
1PKD	THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO-CDK2/CYCLIN A 分子名称: 7-HYDROXYSTAUROSPORINE, Cell division protein kinase 2, Cyclin A2 著者 Johnson, L.N, De Moliner, E, Brown, N.R, Song, H. 登録日 2003-06-05 公開日 2003-06-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Crystal Structure of UCN-01 in Complex with Phospho-CDK2/Cyclin A To be Published
2LSU	The NMR high resolution structure of yeast Tah1 in a free form 分子名称: TPR repeat-containing protein associated with Hsp90 著者 Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X. 登録日 2012-05-07 公開日 2013-05-22 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex. Structure, 21, 2013
2FPW	Crystal Structure of the N-terminal Domain of E.coli HisB- Phosphoaspartate intermediate. 分子名称: CALCIUM ION, Histidine biosynthesis bifunctional protein hisB, ZINC ION 著者 Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2006-01-17 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. J.Biol.Chem., 281, 2006
2NTD	Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations 分子名称: Acidic fibroblast growth factor 1, FORMIC ACID 著者 Dubey, V.K, Blaber, M. 登録日 2006-11-07 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions J.Mol.Biol., 371, 2007

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