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5YZB
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Crystal Structure of Human CRMP-2 with S522D-T509D-T514D-S518D mutations crystallized with GSK3b
分子名称: Dihydropyrimidinase-related protein 2
著者Imasaki, T, Sumi, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R.
登録日2017-12-13
公開日2018-03-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Insights into the Altering Function of CRMP2 by Phosphorylation.
Cell Struct. Funct., 43, 2018
5OL4
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BU of 5ol4 by Molmil
1.28 A resolution of Sporosarcina pasteurii urease inhibited in the presence of NBPT
分子名称: 1,2-ETHANEDIOL, NICKEL (II) ION, Phosphoramidothioic O,O-acid, ...
著者Mazzei, L, Cianci, M, Musiani, F, Ciurli, S.
登録日2017-07-26
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Urease Inhibition in the Presence of N-(n-Butyl)thiophosphoric Triamide, a Suicide Substrate: Structure and Kinetics.
Biochemistry, 56, 2017
5XGX
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BU of 5xgx by Molmil
Crystal structure of colwellia psychrerythraea strain 34H isoaspartyl dipeptidase E80Q mutant complexed with beta-isoaspartyl lysine
分子名称: D-ASPARTIC ACID, D-LYSINE, Isoaspartyl dipeptidase, ...
著者Lee, J.H, Lee, C.W, Park, S.H.
登録日2017-04-18
公開日2018-02-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H.
PLoS ONE, 12, 2017
5YKD
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Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2017-10-14
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for pH-Dependent Oligomerization of Dihydropyrimidinase fromPseudomonas aeruginosaPAO1.
Bioinorg Chem Appl, 2018, 2018
5NKS
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BU of 5nks by Molmil
Human Dihydropyrimidinase-related Protein 4 (DPYSL4, CRMP3, ULIP-4)
分子名称: Dihydropyrimidinase-related protein 4
著者Mathea, S, Elkins, J.M, Strain-Damerell, C, Salah, E, Borkowska, O, Chalk, R, Burgess-Brown, N, Pinkas, D.M, von Delft, F, Krojer, T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
登録日2017-03-31
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Human Dihydropyrimidinase-related Protein 4 (DPYSL4, CRMP3, ULIP-4)
To Be Published
5X1C
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BU of 5x1c by Molmil
Crystal Structure of Human CRMP-2 without C-terminal Tail
分子名称: Dihydropyrimidinase-related protein 2
著者Nitta, R, Tomabechi, Y, Aoki, M, Shirouzu, M.
登録日2017-01-25
公開日2017-09-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structural basis for CRMP2-induced axonal microtubule formation
Sci Rep, 7, 2017
5X1D
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Crystal Structure of T246A-N247A Human CRMP-2 Mutant
分子名称: Dihydropyrimidinase-related protein 2
著者Nitta, R, Tomabechi, Y, Aoki, M, Shirouzu, M.
登録日2017-01-25
公開日2017-09-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for CRMP2-induced axonal microtubule formation
Sci Rep, 7, 2017
5X1A
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BU of 5x1a by Molmil
Crystal Structure of Human CRMP-2
分子名称: Dihydropyrimidinase-related protein 2
著者Nitta, R, Tomabechi, Y, Aoki, M, Shirouzu, M.
登録日2017-01-25
公開日2017-09-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.821 Å)
主引用文献Structural basis for CRMP2-induced axonal microtubule formation
Sci Rep, 7, 2017
5LP3
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BU of 5lp3 by Molmil
Three tetrameric rings of Isoaspartyl Dipeptidase fitted in an EM volume.
分子名称: Isoaspartyl dipeptidase
著者Garcia-Seisdedos, H, Empereur-Mot, C, Elad, N, Levy, E.D.
登録日2016-08-11
公開日2017-07-26
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (10.5 Å)
主引用文献Proteins evolve on the edge of supramolecular self-assembly.
Nature, 548, 2017
5VGM
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BU of 5vgm by Molmil
Crystal structure of dihydroorotase pyrC from Vibrio cholerae in complex with zinc at 1.95 A resolution.
分子名称: ACETATE ION, CHLORIDE ION, Dihydroorotase, ...
著者Lipowska, J, Shabalin, I.G, Miks, C.D, Winsor, J, Cooper, D.R, Shuvalova, L, Kwon, K, Lewinski, K, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-04-11
公開日2017-04-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
Int.J.Biol.Macromol., 136, 2019
5UQC
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BU of 5uqc by Molmil
Crystal structure of mouse CRMP2
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Dihydropyrimidinase-related protein 2
著者Khanna, M, Khanna, R, Perez-Miller, S, Francois-Moutal, L.
登録日2017-02-07
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.
Channels (Austin), 11, 2017
5MKV
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BU of 5mkv by Molmil
Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2) residues 13-516
分子名称: 1,2-ETHANEDIOL, Dihydropyrimidinase-related protein 2
著者Sethi, R, Zheng, Y, Krojer, T, Velupillai, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ahmed, A.A, von Delft, F.
登録日2016-12-05
公開日2017-02-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
5MLE
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BU of 5mle by Molmil
Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2 13-516) Mutant Y479E/Y499E
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dihydropyrimidinase-related protein 2, ...
著者Sethi, R, Zheng, Y, Talon, R, Velupillai, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ahmed, A.A, von Delft, F.
登録日2016-12-06
公開日2017-02-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
5LXX
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BU of 5lxx by Molmil
High-resolution structure of human collapsin response mediator protein 2
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydropyrimidinase-related protein 2, SULFATE ION
著者Myllykoski, M, Hensley, K, Kursula, P.
登録日2016-09-23
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility.
Amino Acids, 49, 2017
5HMD
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BU of 5hmd by Molmil
Crystal structure of triazine hydrolase variant (Y215H/E241Q)
分子名称: Triazine hydrolase, ZINC ION
著者Sugrue, E, Carr, P.D, Jackson, C.J.
登録日2016-01-16
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
5HME
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BU of 5hme by Molmil
Crystal structure of Triazine Hydrolase variant (P214T/Y215H)
分子名称: Triazine hydrolase, ZINC ION
著者Sugrue, E, Carr, P.D, Jackson, C.J.
登録日2016-01-16
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
5HMF
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BU of 5hmf by Molmil
Crystal structure of triazine hydrolase variant (P214T/Y215H/E241Q)
分子名称: Triazine hydrolase, ZINC ION
著者Sugrue, E, Carr, P.D, Jackson, C.J.
登録日2016-01-16
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
5E5C
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BU of 5e5c by Molmil
Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, C.C, Huang, Y.H, Hsieh, Y.C, Tzeng, C.T, Chen, C.J, Huang, C.Y.
登録日2015-10-08
公開日2016-09-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1: Insights into the molecular basis of formation of a dimer
Biochem.Biophys.Res.Commun., 478, 2016
4YIW
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BU of 4yiw by Molmil
DIHYDROOROTASE FROM BACILLUS ANTHRACIS WITH SUBSTRATE BOUND
分子名称: Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ZINC ION
著者Lei, H, Santarsiero, B.D, Rice, A.J, Lee, H, Johnson, M.E.
登録日2015-03-02
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase).
Bioorg.Med.Chem., 24, 2016
4Z42
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BU of 4z42 by Molmil
Crystal structure of urease from Yersinia enterocolitica
分子名称: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ...
著者Studer, G, Jakob, R.P, Mahi, M.A, Wiesand, U, Schwede, T, Maier, T.
登録日2015-04-01
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal structure of urease from Yersinia enterocolitica
To Be Published
5FSE
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BU of 5fse by Molmil
2.07 A resolution 1,4-Benzoquinone inhibited Sporosarcina pasteurii urease
分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ...
著者Mazzei, L, Cianci, M, Musiani, F, Ciurli, S.
登録日2016-01-04
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface.
Dalton Trans, 45, 2016
5FSD
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BU of 5fsd by Molmil
1.75 A resolution 2,5-dihydroxybenzensulfonate inhibited Sporosarcina pasteurii urease
分子名称: 1,2-ETHANEDIOL, 2,5-dihydroxybenzenesulfonic acid, HYDROXIDE ION, ...
著者Mazzei, L, Cianci, M, Musiani, F, Ciurli, S.
登録日2016-01-04
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface.
Dalton Trans, 45, 2016
5A6T
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BU of 5a6t by Molmil
1.65 A resolution Sulphite inhibited Sporosarcina pasteurii urease
分子名称: 1,2-ETHANEDIOL, NICKEL (II) ION, SULFATE ION, ...
著者Mazzei, L, Cianci, M, Benini, S, Bertini, L, Musiani, F, Ciurli, S.
登録日2015-07-01
公開日2015-12-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Kinetic and Structural Studies Reveal a Unique Binding Mode of Sulfite to the Nickel Center in Urease.
J.Inorg.Biochem., 154, 2015
4UB9
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Structural and catalytic characterization of molinate hydrolase
分子名称: Molinate hydrolase, ZINC ION
著者Leite, J.P, Duarte, M, Paiva, A, Ferreira-da-Silva, F, Matias, P.M, Nunes, O, Gales, L.
登録日2014-08-12
公開日2015-06-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides.
Plos One, 10, 2015
4V1X
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BU of 4v1x by Molmil
The structure of the hexameric atrazine chlorohydrolase, AtzA
分子名称: ATRAZINE CHLOROHYDROLASE, DI(HYDROXYETHYL)ETHER, FE (III) ION
著者Peat, T.S, Newman, J, Balotra, S, Lucent, D, Warden, A.C, Scott, C.
登録日2014-10-04
公開日2015-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structure of the Hexameric Atrazine Chlorohydrolase Atza.
Acta Crystallogr.,Sect.D, 71, 2015

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