8PBQ
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8PBM
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8PBN
| Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... | 著者 | del Cano-Ochoa, F, Ramon-Maiques, S. | 登録日 | 2023-06-09 | 公開日 | 2023-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
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8PBR
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8PBT
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8PBU
| Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... | 著者 | del Cano-Ochoa, F, Ramon-Maiques, S. | 登録日 | 2023-06-09 | 公開日 | 2023-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
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8PBS
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6SJ3
| Amidohydrolase, AHS with 3-HBA | 分子名称: | 1,2-ETHANEDIOL, 3-HYDROXYBENZOIC ACID, Amidohydrolase, ... | 著者 | Naismith, J.H, Song, H. | 登録日 | 2019-08-12 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility. Angew.Chem.Int.Ed.Engl., 59, 2020
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2Z29
| Thr109Ala dihydroorotase from E. coli | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | 著者 | Lee, M, Maher, M.J, Guss, J.M. | 登録日 | 2007-05-17 | 公開日 | 2007-10-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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6SJ0
| Amidohydrolase, AHS | 分子名称: | Amidohydrolase, BICARBONATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Naismith, J.H, Song, H. | 登録日 | 2019-08-12 | 公開日 | 2020-01-15 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility. Angew.Chem.Int.Ed.Engl., 59, 2020
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6SJ2
| Amidohydrolase, AHS with 3-HAA | 分子名称: | 3-HYDROXYANTHRANILIC ACID, Amidohydrolase, GLYCEROL, ... | 著者 | Naismith, J.H, Song, H. | 登録日 | 2019-08-12 | 公開日 | 2020-01-15 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility. Angew.Chem.Int.Ed.Engl., 59, 2020
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6SJ1
| Amidohydrolase, AHS | 分子名称: | Amidohydrolase, ZINC ION | 著者 | Naismith, J.H, Song, H. | 登録日 | 2019-08-12 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility. Angew.Chem.Int.Ed.Engl., 59, 2020
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8IHR
| Cryo-EM structure of ochratoxin A-detoxifying amidohydrolase ADH3 in complex with Phe | 分子名称: | Amidohydrolase family protein, PHENYLALANINE, ZINC ION | 著者 | Dai, L.H, Niu, D, Huang, J.-W, Li, X, Shen, P.P, Li, H, Hu, Y.M, Yang, Y, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-02-23 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Cryo-EM structure and rational engineering of a superefficient ochratoxin A-detoxifying amidohydrolase. J Hazard Mater, 458, 2023
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8IHQ
| Cryo-EM structure of ochratoxin A-detoxifying amidohydrolase ADH3 | 分子名称: | Amidohydrolase family protein, ZINC ION | 著者 | Dai, L.H, Niu, D, Huang, J.-W, Li, X, Shen, P.P, Li, H, Hu, Y.M, Yang, Y, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-02-23 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Cryo-EM structure and rational engineering of a superefficient ochratoxin A-detoxifying amidohydrolase. J Hazard Mater, 458, 2023
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5X1C
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8JE0
| A novel amidohydrolase | 分子名称: | 1,2-ETHANEDIOL, Amidase, ZINC ION | 著者 | Ma, D, Feng, R. | 登録日 | 2023-05-15 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A novel amidohydrolase catalyze the degradation of PAM by Klebsiella sp. PCX To Be Published
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5XGW
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5XGX
| Crystal structure of colwellia psychrerythraea strain 34H isoaspartyl dipeptidase E80Q mutant complexed with beta-isoaspartyl lysine | 分子名称: | D-ASPARTIC ACID, D-LYSINE, Isoaspartyl dipeptidase, ... | 著者 | Lee, J.H, Lee, C.W, Park, S.H. | 登録日 | 2017-04-18 | 公開日 | 2018-02-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H. PLoS ONE, 12, 2017
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5YNZ
| Crystal structure of the dihydroorotase domain (K1556A) of human CAD | 分子名称: | CAD protein, ZINC ION | 著者 | Huang, Y.H, Chen, K.L, Cheng, J.H, Huang, C.Y. | 登録日 | 2017-10-26 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.774 Å) | 主引用文献 | Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site Biochem. Biophys. Res. Commun., 505, 2018
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5YKD
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8PBG
| Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... | 著者 | del Cano-Ochoa, F, Ramon-Maiques, S. | 登録日 | 2023-06-09 | 公開日 | 2023-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
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8PBI
| Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... | 著者 | del Cano-Ochoa, F, Ramon-Maiques, S. | 登録日 | 2023-06-09 | 公開日 | 2023-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
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8PBE
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8PBJ
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8PBH
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