PDB: 12280 件ウェブページステータス検索Chemie searchBIRD

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5SXJ	Crystal Structure of PI3Kalpha in complex with fragment 29 分子名称: BENZHYDROXAMIC ACID, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. 登録日 2016-08-09 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Bioorg. Med. Chem., 25, 2017
5SXC	Crystal Structure of PI3Kalpha in complex with fragment 8 分子名称: 5-FLUOROURACIL, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. 登録日 2016-08-09 公開日 2017-02-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Bioorg. Med. Chem., 25, 2017
5SXF	Crystal Structure of PI3Kalpha in complex with fragment 9 分子名称: HYDROXYPHENYL PROPIONIC ACID, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. 登録日 2016-08-09 公開日 2017-02-15 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Bioorg. Med. Chem., 25, 2017
5SXK	Crystal Structure of PI3Kalpha in complex with fragment 18 分子名称: 2-methylbenzene-1,3-diamine, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. 登録日 2016-08-09 公開日 2017-02-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Bioorg. Med. Chem., 25, 2017
5T6C	Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a dichloro-methylpyridinyl-methoxy-phenyl-pyridine piperazine ligand 分子名称: 1-(4-{3,5-dichloro-4-[(2-methylpyridin-3-yl)methoxy]phenyl}pyridin-2-yl)piperazine, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA 著者 Robinson, D.A, Wyatt, P.G. 登録日 2016-09-01 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. J. Med. Chem., 60, 2017

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