PDB: 97310 件ウェブページステータス検索Chemie searchBIRD

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4DLG	Ternary Structure of the large Fragment of Taq DNA polymerase 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA polymerase I, ... 著者 Marx, A, Diederichs, K, Obeid, S, Holzberger, B. 登録日 2012-02-06 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of protein Chem Sci, 3, 2012
7R6Y	E117K mutant pyruvate kinase from rabbit muscle 分子名称: ACETATE ION, MAGNESIUM ION, OXALATE ION, ... 著者 Rodriguez-Romero, A, Rodriguez-Hernandez, A. 登録日 2021-06-24 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The K + -Dependent and -Independent Pyruvate Kinases Acquire the Active Conformation by Different Mechanisms. Int J Mol Sci, 23, 2022
2W97	Crystal Structure of eIF4E Bound to Glycerol and eIF4G1 peptide 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GLYCEROL, ... 著者 Brown, C.J, Verma, C.S, Walkinshaw, M.D, Lane, D.P. 登録日 2009-01-22 公開日 2010-03-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site. Cell Cycle, 8, 2009
8TQO	Eukaryotic translation initiation factor 2B tetramer 分子名称: Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit epsilon, ... 著者 Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P. 登録日 2023-08-08 公開日 2023-12-06 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat.Chem.Biol., 20, 2024
8TQZ	Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit 分子名称: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... 著者 Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P. 登録日 2023-08-08 公開日 2023-12-06 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat.Chem.Biol., 20, 2024
6QIP	Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-MERCAPTOETHANOL, Beta-2-microglobulin, ... 著者 Johansson, E. 登録日 2019-01-21 公開日 2020-02-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative. Biochemistry, 59, 2020
6HR7	HMG-CoA reductase from Methanothermococcus thermolithotrophicus apo form at 2.4 A resolution 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... 著者 Wagner, T, Voegeli, B, Erb, T.J, Shima, S. 登録日 2018-09-26 公開日 2019-02-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme. Febs Lett., 593, 2019
6HR8	HMG-CoA reductase from Methanothermococcus thermolithotrophicus in complex with NADPH at 2.9 A resolution 分子名称: DI(HYDROXYETHYL)ETHER, HMG-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Wagner, T, Voegeli, B, Erb, T.J, Shima, S. 登録日 2018-09-26 公開日 2019-02-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme. Febs Lett., 593, 2019
6RBE	State 2 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C. 登録日 2019-04-10 公開日 2019-06-26 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism. Nat Commun, 10, 2019
5ULI	Crystal Structure of mouse DXO in complex with (3'-NADP)+ and calcium ion 分子名称: CALCIUM ION, Decapping and exoribonuclease protein, [[(2R,3S,4R,5R)-5-(3-aminocarbonyl-4H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate 著者 Doamekpor, S.K, Tong, L. 登録日 2017-01-24 公開日 2017-05-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding. Cell, 168, 2017
5Z11	Crystal Structure of Grass Carp CD8 alpha alpha Homodimers 分子名称: CD8 alpha chain 著者 Wang, J. 登録日 2017-12-22 公開日 2018-04-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structure of the Grass Carp CD8 alpha alpha Homodimers Indicates a Dramatic Evolution of CD8 from Ectotherms to Endotherms. To Be Published
6U34	Binary complex of native hAChE with oxime reactivator RS194B 分子名称: (2E)-N-[2-(azepan-1-yl)ethyl]-2-(hydroxyimino)acetamide, Acetylcholinesterase, GLYCEROL, ... 著者 Kovalevsky, A, Gerlits, O, Radic, Z. 登録日 2019-08-21 公開日 2020-02-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase. J.Biol.Chem., 295, 2020
8APR	CaMct - Mesaconyl-CoA C1:C4 CoA Transferase of Chloroflexus aurantiacus 分子名称: 2-methylfumaryl-CoA isomerase, CHLORIDE ION 著者 Pfister, P, Zarzycki, J, Erb, T.J. 登録日 2022-08-10 公開日 2022-12-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for a Cork-Up Mechanism of the Intra-Molecular Mesaconyl-CoA Transferase. Biochemistry, 62, 2023
7JK4	Structure of Drosophila ORC bound to AT-rich DNA and Cdc6 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (34-MER), ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-27 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
7JGS	Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 2) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-19 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
7JK2	Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-27 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
7JGR	Structure of Drosophila ORC bound to DNA (84 bp) and Cdc6 分子名称: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-19 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
7JK3	Structure of Drosophila ORC bound to GC-rich DNA and Cdc6 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-27 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
3MBY	Ternary complex of DNA Polymerase BETA with template base A and 8oxodGTP in the active site with a dideoxy terminated primer 分子名称: 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Beard, W.A, Hou, E.W, Pedersen, L.C, Prasad, R, Wilson, S.H. 登録日 2010-03-26 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site. Nat.Struct.Mol.Biol., 17, 2010
6Z29	Structure of eIF4G1 (37-49) - PUB1 RRM3 chimera in solution 分子名称: Eukaryotic initiation factor 4F subunit p150,Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 著者 Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M. 登録日 2020-05-15 公開日 2021-05-26 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1, and self-assembly. Front Mol Biosci, 9, 2022
6F09	Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) pSer718 peptide 分子名称: 14-3-3 protein zeta/delta, Ubiquitin carboxyl-terminal hydrolase 8 著者 Centorrino, F, Ballone, A, Ottmann, C, Guo, S, Leysen, S. 登録日 2017-11-17 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.594 Å) 主引用文献 Biophysical and structural insight into the USP8/14-3-3 interaction. FEBS Lett., 592, 2018
1PFX	PORCINE FACTOR IXA 分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, FACTOR IXA 著者 Brandstetter, H, Bauer, M, Huber, R, Lollar, P, Bode, W. 登録日 1995-07-19 公開日 1996-08-17 最終更新日 2013-02-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. Proc.Natl.Acad.Sci.USA, 92, 1995
6GMU	Serum paraoxonase-1 by directed evolution with the L69G/H134R/F222S/T332S mutations 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Ben-David, M, Sussman, J.L, Tawfik, D.S. 登録日 2018-05-28 公開日 2019-04-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition. Mol.Biol.Evol., 37, 2020
6G82	Serum paraoxonase-1 by directed evolution with the L69S/H115W/F222S mutations 分子名称: CALCIUM ION, Serum paraoxonase-1 by directed evolution with the L69S/H115W/F222S mutations 著者 Ben-David, M, Sussman, J.L, Tawfik, D.S. 登録日 2018-04-07 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition. Mol.Biol.Evol., 37, 2020
6H0A	Serum paraoxonase-1 by directed evolution with the L69G/H115W/H134R/F222S/T332S mutations 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, CALCIUM ION, ... 著者 Ben-David, M, Sussman, J.L, Tawfik, D.S. 登録日 2018-07-07 公開日 2019-07-17 最終更新日 2020-04-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition. Mol.Biol.Evol., 37, 2020

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