PDB: 223532 件ウェブページステータス検索Chemie searchBIRD

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5YIE	Crystal Structure of KNI-10742 bound Plasmepsin II (PMII) from Plasmodium falciparum 分子名称: (4R)-3-[(2S,3S)-3-[2-[4-[2-azanylethyl(ethyl)amino]-2,6-dimethyl-phenoxy]ethanoylamino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-N-[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Plasmepsin II, ... 著者 Mishra, V, Rathore, I, Bhaumik, P. 登録日 2017-10-04 公開日 2018-07-11 最終更新日 2019-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights. Febs J., 285, 2018
3OJ7	Crystal structure of a histidine triad family protein from entamoeba histolytica, bound to sulfate 分子名称: Putative histidine triad family protein, SULFATE ION, ZINC ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-08-20 公開日 2010-09-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP. Acta Crystallogr F Struct Biol Commun, 71, 2015
3GM7	1.58 A resolution X-ray structure of (CUG)6 分子名称: 5'-R(*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*G)-3' 著者 Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. 登録日 2009-03-13 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy. Nucleic Acids Res., 37, 2009
5YIC	Crystal Structure of KNI-10333 bound Plasmepsin II (PMII) from Plasmodium falciparum 分子名称: (4R)-3-[(2S,3S)-3-[[(2R)-2-[2-(4-aminophenyl)ethanoylamino]-3-methylsulfanyl-propanoyl]amino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-N-[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, GLYCEROL, ... 著者 Mishra, V, Rathore, I, Bhaumik, P. 登録日 2017-10-03 公開日 2018-07-11 最終更新日 2019-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights. Febs J., 285, 2018
1DD3	CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L12 FROM THERMOTOGA MARITIMA 分子名称: 50S RIBOSOMAL PROTEIN L7/L12 著者 Wahl, M.C, Bourenkov, G.P, Bartunik, H.D, Huber, R. 登録日 1999-11-08 公開日 2000-11-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Flexibility, conformational diversity and two dimerization modes in complexes of ribosomal protein L12. EMBO J., 19, 2000
2LFM	A partially folded structure of amyloid-beta(1 40) in an aqueous environment 分子名称: Beta-amyloid protein 40 著者 Vivekanandan, S, Brender, J.R, Lee, S.Y, Ramamoorthy, A. 登録日 2011-07-06 公開日 2011-07-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A partially folded structure of amyloid-beta(1-40) in an aqueous environment. Biochem.Biophys.Res.Commun., 411, 2011
5YIB	Crystal Structure of KNI-10743 bound Plasmepsin II (PMII) from Plasmodium falciparum 分子名称: (4R)-3-[(2S,3S)-3-[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2,6-dimethyl-phenoxy]ethanoylamino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-N-[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide, 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... 著者 Rathore, I, Mishra, V, Bhaumik, P. 登録日 2017-10-03 公開日 2018-07-11 最終更新日 2019-05-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights. Febs J., 285, 2018
5YID	Crystal Structure of KNI-10395 bound Plasmepsin II (PMII) from Plasmodium falciparum 分子名称: (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-{[S-methyl-N-(phenylacetyl)-L-cysteinyl]amino}-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Plasmepsin II, ... 著者 Mishra, V, Rathore, I, Bhaumik, P. 登録日 2017-10-04 公開日 2018-07-11 最終更新日 2019-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights. Febs J., 285, 2018
6D71	Crystal Structure of the Human Miro1 N-terminal GTPase bound to GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 1 著者 Smith, K.P, Focia, P.J, Rice, S.E, Freymann, D.M. 登録日 2018-04-23 公開日 2019-10-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7180779 Å) 主引用文献 Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase. J.Struct.Biol., 212, 2020
5HU9	Crystal structure of ABL1 in complex with CHMFL-074 分子名称: 1,2-ETHANEDIOL, 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide, CHLORIDE ION, ... 著者 Kong, L.L, Yun, C.H. 登録日 2016-01-27 公開日 2016-07-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.529 Å) 主引用文献 Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) Oncotarget, 7, 2016
5HIW	Sorangium cellulosum So Ce56 cytochrome P450 260B1 分子名称: Cytochrome P450 CYP260B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Salamanca-Pinzon, S.G, Carius, Y, Khatri, Y, Bernhardt, R, Lancaster, C.R.D. 登録日 2016-01-12 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-function analysis for the hydroxylation of Delta 4 C21-steroids by the myxobacterial CYP260B1. Febs Lett., 590, 2016
2LWP	The NMR solution structure of the the ubiquitin homology domain of mouse BAG-1 分子名称: BAG family molecular chaperone regulator 1 著者 Huang, H, Yu, C. 登録日 2012-08-05 公開日 2013-06-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The NMR solution structure of the ubiquitin homology domain of Bcl-2-associated athanogene 1 (BAG-1-UBH) from Mus musculus. Biochem.Biophys.Res.Commun., 431, 2013
3LQY	Crystal structure of putative isochorismatase hydrolase from Oleispira antarctica 分子名称: GLYCEROL, putative isochorismatase hydrolase 著者 Goral, A, Chruszcz, M, Kagan, O, Cymborowski, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2010-02-10 公開日 2010-03-16 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica. J.Struct.Funct.Genom., 13, 2012
2MEM	Solution NMR structure of SLED domain of Scml2 分子名称: Sex comb on midleg-like protein 2 著者 Bezsonova, I. 登録日 2013-09-24 公開日 2014-04-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of the DNA-binding Domain from Scml2 (Sex Comb on Midleg-like 2). J.Biol.Chem., 289, 2014
2LXZ	Solution Structure of the Antimicrobial Peptide Human Defensin 5 分子名称: Defensin-5 著者 Wommack, A.J, Robson, S.A, Wanniarahchi, Y.A, Wan, A, Turner, C.J, Nolan, E.M. 登録日 2012-09-10 公開日 2012-11-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 NMR solution structure and condition-dependent oligomerization of the antimicrobial Peptide human defensin 5. Biochemistry, 51, 2012
2MUH	High-resolution NMR structure of the protegrin-2 docked to DPC Micelles 分子名称: Protegrin-2 著者 Filippov, A.V, Efimov, S.V, Klochkov, V.V, Antzutkin, O.N. 登録日 2014-09-10 公開日 2014-12-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 High-resolution NMR structure of the antimicrobial peptide protegrin-2 in the presence of DPC micelles. J.Biomol.Nmr, 61, 2015
7WZU	Crystal structure of metallo-beta-lactamase IMP-6. 分子名称: Beta-lactamase, ZINC ION 著者 Yamaguchi, Y, Kurosaki, H. 登録日 2022-02-19 公開日 2023-01-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-beta-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution. Acs Infect Dis., 9, 2023
6A82	Crystal structure of the C-terminal periplasmic domain of EcEptC from Escherichia coli 分子名称: Phosphoethanolamine transferase EptC, SODIUM ION 著者 Zhao, Y.Q, Gu, Y.J, Cheng, W. 登録日 2018-07-06 公開日 2018-12-26 最終更新日 2019-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli. FEBS J., 286, 2019
6UTM	Native E. coli Glyceraldehyde 3-phosphate dehydrogenase 分子名称: GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, SN-GLYCEROL-3-PHOSPHATE, ... 著者 Rodriguez-Hernandez, A, Romo-Arevalo, E, Rodriguez-Romero, A. 登録日 2019-10-29 公開日 2019-12-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 A Novel Substrate-Binding Site in the X-Ray Structure of an Oxidized E. coli Glyceraldehyde 3-Phosphate Dehydrogenase Elucidated by Single-Wavelength Anomalous Dispersion Crystals, 9, 2019
5HKE	bile salt hydrolase from Lactobacillus salivarius 分子名称: Bile salt hydrolase, PHOSPHATE ION 著者 Hu, X.-J. 登録日 2016-01-14 公開日 2016-05-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of bile salt hydrolase from Lactobacillus salivarius. Acta Crystallogr F Struct Biol Commun, 72, 2016
4PRF	A Second Look at the HDV Ribozyme Structure and Dynamics. 分子名称: Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A 著者 Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S. 登録日 2014-03-05 公開日 2014-10-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.395 Å) 主引用文献 New tools provide a second look at HDV ribozyme structure, dynamics and cleavage. Nucleic Acids Res., 42, 2014
7VKE	Crystal structure of human CD38 ECD in complex with UniDab(TM) F11A 分子名称: 1,2-ETHANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CHLORIDE ION, ... 著者 Schooten, W.V, Schellenberger, U, Ugamraj, H.S, Manicka, S, Bijpuria, S, Gondu, R.K. 登録日 2021-09-29 公開日 2022-08-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity. Mabs, 14, 2022
5A7B	Structure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan5211 分子名称: 2-[[4-(diethylamino)piperidin-1-yl]methyl]-6-ethynyl-4-(3-phenoxyprop-1-ynyl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C. 登録日 2015-07-03 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere. Acs Chem.Biol., 10, 2015
3MTW	Crystal structure of L-Lysine, L-Arginine carboxypeptidase Cc2672 from Caulobacter Crescentus CB15 complexed with N-methyl phosphonate derivative of L-Arginine 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, L-Arginine carboxypeptidase Cc2672, ... 著者 Fedorov, A.A, Fedorov, E.V, Xiang, D.F, Raushel, F.M, Almo, S.C. 登録日 2010-05-01 公開日 2010-07-28 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Functional Identification and Structure Determination of Two Novel Prolidases from cog1228 in the Amidohydrolase Superfamily Biochemistry, 49, 2010
3MYN	Mutation of Methionine-86 in Dehaloperoxidase-hemoglobin: Effects of the Asp-His-Fe Triad in a 3/3 Globin 分子名称: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Bowden, E.F, de Serrano, V.S, D'Antonio, E.L, Franzen, S. 登録日 2010-05-10 公開日 2011-04-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.194 Å) 主引用文献 Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin. Biochemistry, 50, 2011

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