PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

---

5SPH	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z4718398515 - (R,S) isomer 分子名称: (1R,2S)-1-[4-(methylcarbamamido)benzamido]-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RHK	Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cleavage and polyadenylation specificity factor subunit 4, NITRATE ION, ... 著者 Das, K, Ma, L.-C, Xiao, R, Radvansky, B, Aramini, J, Zhao, L, Arnold, E, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2007-10-09 公開日 2008-07-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for suppression of a host antiviral response by influenza A virus. Proc.Natl.Acad.Sci.Usa, 105, 2008
5SPK	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with REAL250003296134 - (R) isomer 分子名称: 3-[(3R)-1-(6-amino-5-chloropyrimidin-4-yl)piperidin-3-yl]propanoic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RMX	Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A 分子名称: NKG2-A/NKG2-B type II integral membrane protein, Tyrosine-protein phosphatase non-receptor type 6 著者 Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-11-30 公開日 2008-12-02 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structural basis for the recognition of the two NKG2A immunoreceptor tyrosine-based inhibitory motifs (ITIMs) by the C-terminal SH2 domain of protein tyrosine phosphatase SHP-1 To be Published
4V6X	Structure of the human 80S ribosome 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. 登録日 2013-02-27 公開日 2014-07-09 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
8HS3	Gi bound orphan GPR20 in ligand-free state 分子名称: Ggama, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Lin, X, Jiang, S, Xu, F. 登録日 2022-12-16 公開日 2023-03-08 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 The activation mechanism and antibody binding mode for orphan GPR20. Cell Discov, 9, 2023
4USS	Populus trichocarpa glutathione transferase X1-1 (GHR1), complexed with glutathione 分子名称: GLUTATHIONE, GLUTATHIONYL HYDROQUINONE REDUCTASE, PHOSPHATE ION 著者 Lallement, P.A, Meux, E, Gualberto, J.M, Dumaracay, S, Favier, F, Didierjean, C, Saul, F, Haouz, A, Morel-Rouhier, M, Gelhaye, E, Rouhier, N, Hecker, A. 登録日 2014-07-13 公開日 2014-12-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Glutathionyl-Hydroquinone Reductases from Poplar are Plastidial Proteins that Deglutathionylate Both Reduced and Oxidized Glutathionylated Quinones. FEBS Lett., 589, 2015
8HFB	Evolved variant of quercetin 2,4-dioxygenase from Bacillus subtilis 分子名称: 1,2-ETHANEDIOL, GLYCEROL, NICKEL (II) ION, ... 著者 Eom, H, Song, W.J. 登録日 2022-11-10 公開日 2023-03-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Underlying Role of Hydrophobic Environments in Tuning Metal Elements for Efficient Enzyme Catalysis. J.Am.Chem.Soc., 145, 2023
5SPL	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000611664196 - (S,S) isomer 分子名称: Non-structural protein 3, [(2S,4S)-4-methyl-2-(5-methylfuran-2-yl)piperidin-1-yl](7H-pyrrolo[2,3-d]pyrimidin-4-yl)methanone 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RNO	Solution Structure of the N-terminal SAP Domain of SUMO E3 Ligases from Oryza sativa 分子名称: Putative DNA-binding protein 著者 Suzuki, R, Shindo, H, Tase, A, Yamazaki, T. 登録日 2008-01-30 公開日 2008-12-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases from Saccharomyces cerevisiae and Oryza sativa. Proteins, 75, 2009
4UT4	Burkholderia pseudomallei heptokinase WcbL, D-mannose complex. 分子名称: CHLORIDE ION, PUTATIVE SUGAR KINASE, alpha-D-mannopyranose 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-18 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
2RHX	Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine 分子名称: Lethal(3)malignant brain tumor-like protein, N-DIMETHYL-LYSINE, SULFATE ION, ... 著者 Li, H, Patel, D.J. 登録日 2007-10-09 公開日 2007-12-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28, 2007
5SPJ	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000893101964 分子名称: 5-chloro-N~3~-[(4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methyl]pyrazine-2,3-diamine, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
5SPN	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with FRESH00010608284 分子名称: 1-cyclopentyl-3-methyl-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-5-sulfonamide, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4UV2	Structure of the curli transport lipoprotein CsgG in a non-lipidated, pre-pore conformation 分子名称: CURLI PRODUCTION TRANSPORT COMPONENT CSGG 著者 Goyal, P, Krasteva, P.V, Gerven, N.V, Gubellini, F, Broeck, I.V.D, Troupiotis-Tsailaki, A, Jonckheere, W, Pehau-Arnaudet, G, Pinkner, J.S, Chapman, M.R, Hultgren, S.J, Howorka, S, Fronzes, R, Remaut, H. 登録日 2014-08-04 公開日 2014-09-24 最終更新日 2014-12-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg. Nature, 516, 2014
8HBA	Crystal structure of NAD-II riboswitch (single strand) with NAD 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, RNA (55-MER) 著者 Peng, X, Lilley, D.M.J, Huang, L. 登録日 2022-10-27 公開日 2023-03-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Crystal structures of the NAD+-II riboswitch reveal two distinct ligand-binding pockets. Nucleic Acids Res., 51, 2023
2TPT	STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE 分子名称: SULFATE ION, THYMIDINE PHOSPHORYLASE 著者 Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E. 登録日 1997-11-24 公開日 1999-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase. J.Mol.Biol., 281, 1998
8HIL	A cryo-EM structure of B. oleracea RNA polymerase V at 3.57 Angstrom 分子名称: DNA-dependent RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, DNA-directed RNA polymerase subunit, ... 著者 Du, X, Xie, G, Hu, H, Du, J. 登録日 2022-11-20 公開日 2023-03-22 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
5SPB	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5010894404 - (R,R) and (S,S) isomers 分子名称: (1R,2R)-4-hydroxy-1-[4-(phenylcarbamamido)benzamido]-2,3-dihydro-1H-indene-2-carboxylic acid, (1S,2S)-4-hydroxy-1-[4-(phenylcarbamamido)benzamido]-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RIG	CRYSTAL STRUCTURE OF RECOMBINANT RABBIT INTERFERON-GAMMA AT 2.7-ANGSTROMS RESOLUTION 分子名称: INTERFERON-GAMMA 著者 Samudzi, C.T, Burton, L.E, Rubin, J.R. 登録日 1993-01-11 公開日 1993-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of recombinant rabbit interferon-gamma at 2.7-A resolution. J.Biol.Chem., 266, 1991
4UXO	Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... 著者 Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. 登録日 2014-08-27 公開日 2014-09-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
4UZ5	STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM IV - 2.1A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, NOTUM 著者 Zebisch, M, Jones, E.Y. 登録日 2014-09-04 公開日 2015-02-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Notum Deacylates Wnt Proteins to Suppress Signalling Activity. Nature, 519, 2015
8HBS	Crystal of rAlfNmt 分子名称: Glycylpeptide N-tetradecanoyltransferase 著者 Wang, Y, Wang, S. 登録日 2022-10-30 公開日 2023-03-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 N -Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus. Microbiol Spectr, 11, 2023
2ROB	Solution structure of calcium bound soybean calmodulin isoform 4 C-terminal domain 分子名称: CALCIUM ION, Calmodulin 著者 Ishida, H, Huang, H, Yamniuk, A.P, Takaya, Y, Vogel, H.J. 登録日 2008-03-14 公開日 2008-04-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structures of two soybean calmodulin isoforms provide a structural basis for their selective target activation properties J.Biol.Chem., 283, 2008
5SOL	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000910475722 - (S,R) isomer 分子名称: (8S)-8-fluoro-6-(6-{[(2R)-2-hydroxypropyl]amino}pyrimidin-4-yl)-6-azaspiro[3.4]octane-8-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023

<429430431432433434435436437438439440441442443444>