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6AKK
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BU of 6akk by Molmil
Crystal structure of the second Coiled-coil domain of SIKE1
分子名称: GLYCEROL, Suppressor of IKBKE 1
著者Zhou, L, Chen, M, Zhou, Z.C.
登録日2018-09-02
公開日2019-01-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
3H7F
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BU of 3h7f by Molmil
Crystal structure of serine hydroxymethyltransferase from Mycobacterium tuberculosis
分子名称: MAGNESIUM ION, Serine hydroxymethyltransferase 1
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-04-24
公開日2009-05-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
6A2O
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BU of 6a2o by Molmil
Crystal structure of wild type Plasmodium falciparum DHFR-TS complexed with BT3, NADPH, and dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5,5'-[propane-1,3-diylbis(oxy-4,1-phenylene)]bis(6-ethylpyrimidine-2,4-diamine), Bifunctional dihydrofolate reductase-thymidylate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y.
登録日2018-06-12
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
6A2M
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BU of 6a2m by Molmil
Crystal structure of wild type Plasmodium falciparum DHFR-TS complexed with BT2, NADPH, and dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y.
登録日2018-06-12
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
6AKL
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BU of 6akl by Molmil
Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain
分子名称: Striatin-3, Suppressor of IKBKE 1
著者Zhou, L, Chen, M, Zhou, Z.C.
登録日2018-09-02
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
3GOX
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BU of 3gox by Molmil
Crystal structure of the beta-beta-alpha-Me type II restriction endonuclease Hpy99I in the absence of EDTA
分子名称: 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', PENTAETHYLENE GLYCOL, ...
著者Sokolowska, M, Czapinska, H, Bochtler, M.
登録日2009-03-20
公開日2009-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Nucleic Acids Res., 37, 2009
4EO9
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BU of 4eo9 by Molmil
Crystal structure of a phosphoglycerate mutase gpm1 from Mycobacterium leprae
分子名称: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, CHLORIDE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-04-13
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3ORZ
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BU of 3orz by Molmil
PDK1 mutant bound to allosteric disulfide fragment activator 2A2
分子名称: 3-(1H-INDOL-3-YL)-4-{1-[2-(1-METHYLPYRROLIDIN-2-YL)ETHYL]-1H-INDOL-3-YL}-1H-PYRROLE-2,5-DIONE, 3-phosphoinositide-dependent protein kinase 1, 4-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxobutane-1-thiol
著者Sadowsky, J.D, Wells, J.A.
登録日2010-09-08
公開日2011-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9995 Å)
主引用文献Turning a protein kinase on or off from a single allosteric site via disulfide trapping.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OSP
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BU of 3osp by Molmil
Structure of rev1
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ...
著者Nair, D.T, Aggarwal, A.K.
登録日2010-09-09
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase.
J.Mol.Biol., 406, 2011
6A2K
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BU of 6a2k by Molmil
Crystal structure of wild type Plasmodium falciparum DHFR-TS complexed with BT1, NADPH, and dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y.
登録日2018-06-12
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
3H2J
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BU of 3h2j by Molmil
Crystal structure of the rice cell wall degrading esterase LipA from Xanthomonas oryzae
分子名称: esterase
著者Aparna, G, Chatterjee, A, Sonti, R.V, Sankaranarayanan, R.
登録日2009-04-14
公開日2009-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A Cell Wall-Degrading Esterase of Xanthomonas oryzae Requires a Unique Substrate Recognition Module for Pathogenesis on Rice
Plant Cell, 21, 2009
2P50
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BU of 2p50 by Molmil
Crystal structure of N-acetyl-D-Glucosamine-6-Phosphate deacetylase liganded with Zn
分子名称: N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C.
登録日2007-03-14
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase.
Biochemistry, 46, 2007
3D9Y
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BU of 3d9y by Molmil
Crystal Structure of Profilin from Schizosaccharomyces pombe
分子名称: GLYCEROL, Profilin
著者Ezezika, O.C, Nolen, B.J, Pollard, T.D.
登録日2008-05-28
公開日2008-12-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN.
J.Biol.Chem., 284, 2009
3OWV
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BU of 3owv by Molmil
Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae
分子名称: CHLORIDE ION, DNA-entry nuclease, MAGNESIUM ION
著者Moon, A.F, Midon, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
登録日2010-09-20
公開日2010-12-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
Nucleic Acids Res., 39, 2011
3P2Y
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BU of 3p2y by Molmil
Crystal structure of alanine dehydrogenase/pyridine nucleotide transhydrogenase from Mycobacterium smegmatis
分子名称: 1,2-ETHANEDIOL, Alanine dehydrogenase/pyridine nucleotide transhydrogenase, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-10-04
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3OME
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BU of 3ome by Molmil
Crystal structure of a probable ENOYL-COA Hydratase from Mycobacterium Smegmatis
分子名称: Enoyl-CoA hydratase, ZINC ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-26
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
2QDL
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BU of 2qdl by Molmil
Crystal structure of scaffolding protein TtCheW from Thermoanaerobacter tengcongensis
分子名称: Chemotaxis signal transduction protein, GLYCEROL
著者Yao, W, Shi, L, Liang, D.C.
登録日2007-06-21
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of scaffolding protein CheW from thermoanaerobacter tengcongensis.
Biochem.Biophys.Res.Commun., 361, 2007
4FPV
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BU of 4fpv by Molmil
Crystal structure of D. rerio TDP2 complexed with single strand DNA product
分子名称: DNA (5'-D(P*TP*GP*CP*AP*G)-3'), GLYCEROL, MAGNESIUM ION, ...
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2012-06-22
公開日2012-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Nat.Struct.Mol.Biol., 19, 2012
2QZL
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BU of 2qzl by Molmil
Crystal Structure of human Beta Secretase complexed with IXS
分子名称: Beta-secretase 1, N-[(1S)-1-benzyl-2-{[(1S)-2-(isobutylamino)-1-methyl-2-oxoethyl]amino}ethyl]-N'-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]isophthalamide
著者Munshi, S.
登録日2007-08-16
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献BACE-1 inhibition by a series of psi[CH2NH] reduced amide isosteres
Bioorg.Med.Chem.Lett., 16, 2006
3H0G
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BU of 3h0g by Molmil
RNA Polymerase II from Schizosaccharomyces pombe
分子名称: DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
著者Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D.
登録日2009-04-09
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Proc.Natl.Acad.Sci.USA, 106, 2009
3QKA
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BU of 3qka by Molmil
Crystal structure of enoyl-CoA hydratase EchA5 from Mycobacterium marinum
分子名称: Enoyl-CoA hydratase, EchA5
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-01-31
公開日2011-02-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4GC8
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BU of 4gc8 by Molmil
Crystal structure of FliM middle domain from H. pylori
分子名称: Flagellar motor switch protein
著者Lam, K.H, Au, S.W.N.
登録日2012-07-30
公開日2013-05-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of FliG-FliM interaction in Helicobacter pylori
Mol.Microbiol., 88, 2013
4FXF
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BU of 4fxf by Molmil
Structure of M2 pyruvate kinase in complex with phenylalanine
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Walkinshaw, M.D, Morgan, H.P.
登録日2012-07-03
公開日2013-03-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4G0S
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BU of 4g0s by Molmil
Crystal Structure of Epiphyas postvittana Takeout 1 expressed in Sf9 cells
分子名称: MYRISTIC ACID, Takeout-like protein 1
著者Hamiaux, C, Baker, E.N, Newcomb, R.D.
登録日2012-07-10
公開日2013-05-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.191 Å)
主引用文献Ligand promiscuity within the internal cavity of Epiphyas postvittana Takeout 1 protein.
J.Struct.Biol., 182, 2013
3QLJ
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BU of 3qlj by Molmil
Crystal structure of a short chain dehydrogenase from Mycobacterium avium
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-02-02
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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