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7S6M
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Human PARP1 deltaV687-E688 bound to a DNA double strand break.
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*CP*G)-3'), ...
著者Rouleau-Turcotte, E, Pascal, J.M.
登録日2021-09-14
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery.
Mol.Cell, 82, 2022
8C7O
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BU of 8c7o by Molmil
Unliganded transcriptional pleiotropic repressor CodY from Staphylococcus aureus
分子名称: ACETATE ION, Global transcriptional regulator CodY, SULFATE ION
著者Hainzl, T, Sauer-Eriksson, A.E.
登録日2023-01-16
公開日2023-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insights into CodY activation and DNA recognition.
Nucleic Acids Res., 51, 2023
7E5W
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BU of 7e5w by Molmil
The structure of CcpA from Staphylococcus aureus
分子名称: Catabolite control protein A, SULFATE ION
著者Yu, G, Wei, X.
登録日2021-02-20
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation.
J.Biol.Chem., 298, 2022
6LTP
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BU of 6ltp by Molmil
Crystal structure of Cas12i2 binary complex
分子名称: Cas12i2, crRNA (56-mer RNA)
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-23
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
2MAM
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BU of 2mam by Molmil
Solution structure of the interdigitated double Tudor domain of RBBP1
分子名称: AT-rich interactive domain-containing protein 4A
著者Gong, W, Feng, Y.
登録日2013-07-15
公開日2014-01-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Retinoblastoma-binding protein 1 has an interdigitated double Tudor domain with DNA binding activity.
J.Biol.Chem., 289, 2014
5FTC
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BU of 5ftc by Molmil
Crystal structure of Pif1 helicase from Bacteroides in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, TPR DOMAIN PROTEIN
著者Chen, W.-F, Dai, Y.-X, Duan, X.-L, Liu, N.-N, Shi, W, Li, M, Dou, S.-X, Li, N, Dong, Y.-H, Rety, S, Xi, X.-G.
登録日2016-01-12
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.269 Å)
主引用文献Crystal Structures of the Bspif1 Helicase Reveal that a Major Movement of the 2B SH3 Domain is Required for DNA Unwinding
Nucleic Acids Res., 44, 2016
3FGH
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BU of 3fgh by Molmil
Human mitochondrial transcription factor A box B
分子名称: CADMIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Gangelhoff, T.A, Mungalachetty, P, Nix, J, Churchill, M.E.A.
登録日2008-12-06
公開日2009-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A
Nucleic Acids Res., 37, 2009
5FTD
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BU of 5ftd by Molmil
Crystal structure of Pif1 helicase from Bacteroides apo form
分子名称: PHOSPHATE ION, TPR DOMAIN PROTEIN
著者Chen, W.-F, Dai, Y.-X, Duan, X.-L, Liu, N.-N, Shi, W, Li, M, Dou, S.-X, Li, N, Dong, Y.-H, Rety, S, Xi, X.-G.
登録日2016-01-12
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Crystal Structures of the Bspif1 Helicase Reveal that a Major Movement of the 2B SH3 Domain is Required for DNA Unwinding
Nucleic Acids Res., 44, 2016
5FTF
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BU of 5ftf by Molmil
Crystal structure of Pif1 helicase from Bacteroides double mutant L95C-I339C
分子名称: ADENOSINE-5'-DIPHOSPHATE, TPR DOMAIN PROTEIN
著者Chen, W.-F, Dai, Y.-X, Duan, X.-L, Liu, N.-N, Shi, W, Li, M, Dou, S.-X, Li, N, Dong, Y.-H, Rety, S, Xi, X.-G.
登録日2016-01-13
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.412 Å)
主引用文献Crystal Structures of the Bspif1 Helicase Reveal that a Major Movement of the 2B SH3 Domain is Required for DNA Unwinding
Nucleic Acids Res., 44, 2016
6G6J
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BU of 6g6j by Molmil
The crystal structures of Human MYC:MAX bHLHZip complex
分子名称: Myc proto-oncogene protein, Protein max, SULFATE ION
著者Allen, M.D, Zinzalla, G.
登録日2018-04-01
公開日2019-04-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.
Biochemistry, 58, 2019
7P3F
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BU of 7p3f by Molmil
Streptomyces coelicolor dATP/ATP-loaded NrdR in complex with its cognate DNA
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
著者Martinez-Carranza, M, Stenmark, P.
登録日2021-07-07
公開日2022-05-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
6G6K
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BU of 6g6k by Molmil
The crystal structures of Human MYC:MAX bHLHZip complex
分子名称: CHLORIDE ION, Myc proto-oncogene protein, Protein max
著者Allen, M.D, Zinzalla, G.
登録日2018-04-01
公開日2019-04-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.
Biochemistry, 58, 2019
3MUJ
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BU of 3muj by Molmil
Early B-cell factor 3 (EBF3) IPT/TIG and dimerization helices
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Transcription factor COE3
著者Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schueler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC)
登録日2010-05-03
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif.
J.Biol.Chem., 285, 2010
6G6L
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BU of 6g6l by Molmil
The crystal structures of Human MYC:MAX bHLHZip complex
分子名称: Myc proto-oncogene protein, Protein max, SULFATE ION
著者Allen, M.D, Zinzalla, G.
登録日2018-04-01
公開日2019-04-10
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.
Biochemistry, 58, 2019
4G0V
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BU of 4g0v by Molmil
Human topoisomerase iibeta in complex with DNA and mitoxantrone
分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
著者Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
登録日2012-07-10
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
5FTB
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BU of 5ftb by Molmil
Crystal structure of Pif1 helicase from Bacteroides in complex with AMPPNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, POTASSIUM ION, ...
著者Chen, W.-F, Dai, Y.-X, Duan, X.-L, Liu, N.-N, Shi, W, Li, M, Dou, S.-X, Li, N, Dong, Y.-H, Rety, S, Xi, X.-G.
登録日2016-01-12
公開日2016-02-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Crystal Structures of the Bspif1 Helicase Reveal that a Major Movement of the 2B SH3 Domain is Required for DNA Unwinding
Nucleic Acids Res., 44, 2016
7D11
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BU of 7d11 by Molmil
Solution structure of a WKRY DNA-binding domain
分子名称: WRKY transcription factor 1, ZINC ION
著者Li, Q.W, Hu, Y.F, Jin, C.W.
登録日2020-09-12
公開日2021-09-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of a WKRY DNA-binding domain
To Be Published
1D1M
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BU of 1d1m by Molmil
CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT
分子名称: LAMBDA CRO REPRESSOR
著者Rupert, P.B, Mollah, A.K, Mossing, M.C, Matthews, B.W.
登録日1999-09-17
公開日1999-09-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The structural basis for enhanced stability and reduced DNA binding seen in engineered second-generation Cro monomers and dimers.
J.Mol.Biol., 296, 2000
4K8F
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BU of 4k8f by Molmil
Structure of the heme domain of CooA from Rhodospirillum rubrum
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator, Crp/Fnr family
著者Kuchinskas, M, Li, H, Poulos, T.L.
登録日2013-04-18
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The role of the DNA-binding domains in CooA activation.
Biochemistry, 45, 2006
6M9K
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BU of 6m9k by Molmil
Crystal structure of lambda exonuclease in complex with the Red beta C-terminal domain
分子名称: Exonuclease, Recombination protein bet, SULFATE ION
著者Bell, C.E, Caldwell, B.J.
登録日2018-08-23
公開日2019-01-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Red beta C-terminal domain in complex with lambda Exonuclease reveals an unexpected homology with lambda Orf and an interaction with Escherichia coli single stranded DNA binding protein.
Nucleic Acids Res., 47, 2019
7KLF
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BU of 7klf by Molmil
Ternary structure of Dpo4 bound to G in the template base paired with incoming dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*GP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2020-10-30
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
To Be Published
7KLE
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BU of 7kle by Molmil
Ternary structure of Dpo4 bound to N7mG in the template base paired with incoming dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*(FMG)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2020-10-30
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
To Be Published
5OFN
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BU of 5ofn by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
分子名称: DNA primase large subunit PriL,PriL-X fusion protein, DNA primase small subunit PriS, ZINC ION
著者Pellegrini, L, Holzer, S.
登録日2017-07-11
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
6WAF
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BU of 6waf by Molmil
Crystal Structure of SmcR N55I from Vibrio vulnificus
分子名称: LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.381 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
6WAH
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BU of 6wah by Molmil
Crystal Structure of SmcR L139R from Vibrio vulnificus
分子名称: 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021

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件を2024-09-04に公開中

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