8V84
| 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | 著者 | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | 登録日 | 2023-12-04 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
|
|
7B3O
| |
8V87
| 60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | 著者 | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | 登録日 | 2023-12-04 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
|
|
8V83
| 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | 著者 | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | 登録日 | 2023-12-04 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
|
|
7DOK
| |
4X1T
| The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP | 分子名称: | 1,2-ETHANEDIOL, Monogalactosyldiacylglycerol synthase 1, chloroplastic, ... | 著者 | Rocha, J, Breton, C. | 登録日 | 2014-11-25 | 公開日 | 2016-02-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural insights and membrane binding properties of MGD1, the major galactolipid synthase in plants. Plant J., 85, 2016
|
|
6LH6
| |
6YLY
| pre-60S State NE2 (TAP-Flag-Nop53) | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Beckmann, R. | 登録日 | 2020-04-07 | 公開日 | 2020-07-29 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Mol.Cell, 79, 2020
|
|
6YLX
| pre-60S State NE1 (TAP-Flag-Nop53) | 分子名称: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | 著者 | Kater, L, Beckmann, R. | 登録日 | 2020-04-07 | 公開日 | 2020-07-29 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Mol.Cell, 79, 2020
|
|
7U0H
| State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | 分子名称: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | 登録日 | 2022-02-18 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
|
|
7UQB
| Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-19 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
|
|
7UOO
| Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-13 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
|
|
7UQZ
| Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-20 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
|
|
7V08
| Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-05-10 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
|
|
7SG5
| |
7SG6
| |
7RWN
| Crystal Structure of BPTF bromodomain in complex with 4-chloro-5-{4-[(dimethylamino)methyl]anilino}-2-methylpyridazin-3(2H)-one | 分子名称: | 1,2-ETHANEDIOL, 4-chloro-5-{4-[(dimethylamino)methyl]anilino}-2-methylpyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF | 著者 | Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-20 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. J.Med.Chem., 64, 2021
|
|
7RWP
| Crystal Structure of BPTF bromodomain in complex with 5-[4-(aminomethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one | 分子名称: | 5-[4-(aminomethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one, CALCIUM ION, Nucleosome-remodeling factor subunit BPTF | 著者 | Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-20 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. J.Med.Chem., 64, 2021
|
|
7RWQ
| Crystal Structure of BPTF bromodomain in complex with 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyridazin-3(2H)-one | 分子名称: | 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyridazin-3(2H)-one, CALCIUM ION, Nucleosome-remodeling factor subunit BPTF | 著者 | Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-20 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. J.Med.Chem., 64, 2021
|
|
7RWO
| Crystal Structure of BPTF bromodomain in complex with 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyridazin-3(2H)-one | 分子名称: | 1,2-ETHANEDIOL, 4-chloro-2-methyl-5-[(1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF | 著者 | Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-20 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. J.Med.Chem., 64, 2021
|
|
4EY8
| Crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, Fasciculin-2, ... | 著者 | Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M. | 登録日 | 2012-05-01 | 公開日 | 2012-10-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5958 Å) | 主引用文献 | Structures of human acetylcholinesterase in complex with pharmacologically important ligands. J.Med.Chem., 55, 2012
|
|
5Z3G
| Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Zhu, X, Zhou, D, Ye, K. | 登録日 | 2018-01-06 | 公開日 | 2018-04-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell, 10, 2019
|
|
6EM1
| State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
|
|
4U1E
| Crystal structure of the eIF3b-CTD/eIF3i/eIF3g-NTD translation initiation complex | 分子名称: | Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 3 subunit I | 著者 | Zhang, S, Erzberger, J.P, Schaefer, T, Ban, N. | 登録日 | 2014-07-15 | 公開日 | 2014-09-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex. Cell, 158, 2014
|
|
6EM3
| State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
|
|