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4N90
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Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody
分子名称: Fab heavy chain, Fab light chain, Tumor necrosis factor ligand superfamily member 10, ...
著者Huang, X.
登録日2013-10-18
公開日2014-09-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity.
Cancer Cell, 26, 2014
7AV9
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BU of 7av9 by Molmil
Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2
分子名称: 1,2-ETHANEDIOL, PH-interacting protein
著者Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F.
登録日2020-11-04
公開日2021-01-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2
To Be Published
7AV8
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Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212
分子名称: PH-interacting protein
著者Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC)
登録日2020-11-04
公開日2021-01-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212
To Be Published
6NMI
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BU of 6nmi by Molmil
Cryo-EM structure of the human TFIIH core complex
分子名称: CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ...
著者Greber, B.J, Toso, D, Fang, J, Nogales, E.
登録日2019-01-10
公開日2019-03-13
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The complete structure of the human TFIIH core complex.
Elife, 8, 2019
6OD1
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IraD-bound to RssB D58P variant
分子名称: Anti-adapter protein IraD, Regulator of RpoS
著者Deaconescu, A.M, Dorich, V.
登録日2019-03-25
公開日2019-04-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for inhibition of a response regulator of sigmaSstability by a ClpXP antiadaptor.
Genes Dev., 33, 2019
5NJT
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BU of 5njt by Molmil
Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N.
登録日2017-03-29
公開日2017-06-14
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.
EMBO J., 36, 2017
1S5V
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BU of 1s5v by Molmil
Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue Tyr107 to Phe107
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
2GTL
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BU of 2gtl by Molmil
Lumbricus Erythrocruorin at 3.5A resolution
分子名称: CALCIUM ION, CARBON MONOXIDE, Extracellular globin 2, ...
著者Royer Jr, W.E, Sharma, H, Strand, K, Knapp, J.E, Bhyravbhatla, B.
登録日2006-04-28
公開日2006-07-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Lumbricus erythrocruorin at 3.5 a resolution: architecture of a megadalton respiratory complex.
Structure, 14, 2006
5M5Y
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BU of 5m5y by Molmil
RNA Polymerase I elongation complex 2
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W.
登録日2016-10-23
公開日2016-12-21
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
5M5X
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BU of 5m5x by Molmil
RNA Polymerase I elongation complex 1
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W.
登録日2016-10-23
公開日2016-12-21
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
4NFN
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Human tau tubulin kinase 1 (TTBK1) complexed with 3-({5-[(4-amino-4-methylpiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-bromophenol
分子名称: 3-({5-[(4-amino-4-methylpiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-bromophenol, SULFATE ION, Tau-tubulin kinase 1
著者Sheriff, S.
登録日2013-10-31
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor.
Acta Crystallogr F Struct Biol Commun, 70, 2014
5N60
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BU of 5n60 by Molmil
Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation I)
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P.
登録日2017-02-14
公開日2017-04-05
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
6VJ4
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BU of 6vj4 by Molmil
1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis
分子名称: Peptidylprolyl isomerase PrsA
著者Minasov, G, Shuvalova, L, Kiryukhina, O, Wiersum, G, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-01-14
公開日2020-02-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis
To Be Published
1PAA
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BU of 1paa by Molmil
STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION
分子名称: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
著者Bernstein, B.E, Hoffman, R.C, Horvath, S.J, Herriott, J.R, Klevit, R.E.
登録日1994-07-15
公開日1994-10-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition.
Biochemistry, 33, 1994
5N61
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BU of 5n61 by Molmil
RNA polymerase I initially transcribing complex
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P.
登録日2017-02-14
公開日2017-04-05
最終更新日2019-10-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
2H9G
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BU of 2h9g by Molmil
Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5)
分子名称: Fab BdF1, heavy chain, light chain, ...
著者Hymowitz, S.G, Compaan, D.M.
登録日2006-06-09
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists.
J.Mol.Biol., 361, 2006
1S5T
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BU of 1s5t by Molmil
Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue thr44 to val44
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
1ZA3
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BU of 1za3 by Molmil
The crystal structure of the YSd1 Fab bound to DR5
分子名称: Fab-YSd1 heavy chain, Fab-YSd1 light chain, Tumor necrosis factor receptor superfamily member 10B
著者Fellouse, F.A, Li, B, Compaan, D.M, Peden, A.A, Hymowitz, S.G, Sidhu, S.S.
登録日2005-04-05
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Molecular recognition by a binary code.
J.Mol.Biol., 348, 2005
2A6N
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BU of 2a6n by Molmil
Dihydrodipicolinate synthase (E. coli)- mutant R138A
分子名称: Dihydrodipicolinate synthase, POTASSIUM ION
著者Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A.
登録日2005-07-03
公開日2005-10-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
7YAN
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BU of 7yan by Molmil
UDP-glucuronosyltransferase2B17 C-terminal domain
分子名称: L(+)-TARTARIC ACID, UDP-glucuronosyltransferase 2B17
著者Wang, C.Y, Zhang, L.
登録日2022-06-28
公開日2023-07-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献UDP-glucuronosyltransferase2B17 C-terminal domain
To Be Published
7YF5
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Crystal Structure of the UDPGA Binding Domain of the Human Phase II Metabolizing Enzyme UDP-Glucuronosyltransferase 2B10
分子名称: SULFATE ION, UDP-glucuronosyltransferase 2B10
著者Yin, X.L, Tong, J.S.
登録日2022-07-07
公開日2023-07-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.527 Å)
主引用文献Crystal Structure Determination of Nucleotide-sugar Binding Domain of Human UDP-glucuronosyltransferases 2B10.
Protein Pept.Lett., 30, 2023
7QHW
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TTBK1 kinase domain in complex with inhibitor 29
分子名称: GLYCEROL, SULFATE ION, Tau-tubulin kinase 1, ...
著者Nozal, V, Liehta, D.
登録日2021-12-14
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
1YXD
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Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A
分子名称: CHLORIDE ION, LYSINE, POTASSIUM ION, ...
著者Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A.
登録日2005-02-20
公開日2005-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
8QPP
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Bacillus subtilis MutS2-collided disome complex (stalled 70S)
分子名称: 16S rRNA (1533-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R.
登録日2023-10-02
公開日2023-12-27
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Embo J., 43, 2024
7Q8V
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Crystal structure of TTBK1 in complex with VNG2.73 (compound 42)
分子名称: PHOSPHATE ION, Tau-tubulin kinase 1, ~{N}-[4-(2-chloranylphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine
著者Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
登録日2021-11-11
公開日2022-03-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022

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