PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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7LNT	Ternary complex of the Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus bound to benzyl monophosphate and ATP 分子名称: (phenylmethyl) dihydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R. 登録日 2021-02-08 公開日 2021-12-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
7LES	Acanthamoeba castellanii CYP51 (AcCYP51)-Imidazole complex 分子名称: DI(HYDROXYETHYL)ETHER, FORMIC ACID, IMIDAZOLE, ... 著者 Sharma, V, Podust, L.M. 登録日 2021-01-15 公開日 2021-12-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Homodimerization Counteracts the Detrimental Effect of Nitrogenous Heme Ligands on the Enzymatic Activity of Acanthamoeba castellanii CYP51. Biochemistry, 61, 2022
3USQ	Structure of D159S/Y194F glycogenin mutant truncated at residue 270 分子名称: CHLORIDE ION, GLYCEROL, Glycogenin-1 著者 Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A. 登録日 2011-11-23 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mechanisms of monomeric and dimeric glycogenin autoglucosylation. J.Biol.Chem., 287, 2012
7LNV	Apo Structure of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus 分子名称: GLYCEROL, Isopentenyl phosphate kinase, MALONATE ION 著者 Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R. 登録日 2021-02-08 公開日 2021-12-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
7LUH	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment bromophenoxy propanamide 分子名称: (2~{R})-2-(4-bromanylphenoxy)propanamide, Thiol:disulfide interchange protein 著者 Petit, G.A, Martin, J.L, McMahon, R.M. 登録日 2021-02-22 公開日 2022-01-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LUJ	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment 4-methoxy-N-phenylbenzenesulfonamide 分子名称: 4-methoxy-~{N}-phenyl-benzenesulfonamide, SULFATE ION, Thiol:disulfide interchange protein 著者 Petit, G.A, Martin, J.L, McMahon, R.M. 登録日 2021-02-22 公開日 2022-01-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LL4	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-114. 分子名称: Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[3-fluoro-4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile 著者 Karim, M.R, Schonbrunn, E. 登録日 2021-02-03 公開日 2022-01-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 High-resolution crystal structure of human Janus Kinase 2 kinase domain (JH1) bound to PN5-114. To Be Published
7LAT	Campylobacter jejuni keto-acid reductoisomerase in complex with Mg2+ 分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION 著者 Guddat, L.W. 登録日 2021-01-06 公開日 2022-01-12 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase Acs Catalysis, 2024
4OU3	Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... 著者 Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F. 登録日 2014-02-14 公開日 2014-11-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy. J.Biol.Chem., 289, 2014
7LL5	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. 分子名称: 1,2-ETHANEDIOL, Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile 著者 Karim, M.R, Schonbrunn, E. 登録日 2021-02-03 公開日 2022-01-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. To Be Published
7LSQ	The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer 分子名称: 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline, ACETATE ION, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2021-02-18 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.67130542 Å) 主引用文献 Design of Large Stokes Shift Fluorescent Proteins Based on Excited State Proton Transfer of an Engineered Photobase. J.Am.Chem.Soc., 143, 2021
7M1E	Structural and functional studies about scorpine showed the presence of blocking channel and cytolytic activities as well as two different structural domains 分子名称: Scorpine 著者 del Rio, J.F, Lopez, A.E, Titaux, G. 登録日 2021-03-12 公開日 2022-01-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and functional studies of scorpine: A channel blocker and cytolytic peptide. Toxicon, 222, 2022
7LAF	15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor 分子名称: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B 著者 Newcomer, M.E, Gilbert, N.C, Neau, D.B. 登録日 2021-01-06 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2. Bioorg.Med.Chem., 46, 2021
7L91	Structure of Metallo Beta-Lactamase L1 in a Complex with Hydrolyzed Moxalactam Determined by Pink-Beam Serial Crystallography 分子名称: (2R)-2-[(R)-carboxy{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}methoxymethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, Putative metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase), ZINC ION 著者 Wilamowski, M, Kim, Y, Sherrell, D.A, Lavens, A, Henning, R, Maltseva, N, Endres, M, Babnigg, G, Vukica, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-01-01 公開日 2022-02-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase. Nat Commun, 13, 2022
7LVE	Jug r 2 Leader Sequence Residues 117-161 分子名称: Vicilin Jug r 2.0101 著者 Mueller, G.A, Foo, A.C.Y, DeRose, E.F. 登録日 2021-02-25 公開日 2022-02-02 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides. J.Agric.Food Chem., 70, 2022
7LH6	The structure of Bacteroides plebeius L-galactose dehydrogenase 分子名称: L-galactose dehydrogenase 著者 Robb, C.S, Pluvinage, B, Vickers, C, Boraston, A.B. 登録日 2021-01-21 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Metabolism of a hybrid algal galactan by members of the human gut microbiome. Nat.Chem.Biol., 18, 2022
5JY7	Complex of Mycobacterium smegmatis trehalose synthase with maltokinase 分子名称: CALCIUM ION, Maltokinase, Trehalose synthase/amylase TreS 著者 Futterer, K, Kermani, A.A, Besra, G.S. 登録日 2016-05-13 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Crystal structure of the TreS-Pep2 complex, initiating alpha-glucan synthesis in the GlgE pathway of mycobacteria. J.Biol.Chem., 2019
4FQR	Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing antibody C05, ... 著者 Ekiert, D.C, Wilson, I.A. 登録日 2012-06-25 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489, 2012
7LJP	Structure of Thermotoga maritima SmpB 分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ... 著者 Chan, C.W, Mondragon, A. 登録日 2021-01-29 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Thermotoga maritima SmpB reveals its C-terminal tail domain in a helical conformation mimicking that of a ribosome-bound state To Be Published
7LFF	Crystal structure of the Candida albicans kinesin-8 motor domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION 著者 Allingham, J.S, Hunter, B. 登録日 2021-01-16 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7LGG	Asymmetric unit for phage Qbeta oblate particle 分子名称: Capsid protein 著者 Chang, J.Y, Zhang, J. 登録日 2021-01-20 公開日 2022-01-26 最終更新日 2022-03-09 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural Assembly of Q beta Virion and Its Diverse Forms of Virus-like Particles. Viruses, 14, 2022
7LGH	Asymmetric unit for phage Qbeta small prolate particle 分子名称: Capsid protein 著者 Chang, J.Y, Zhang, J. 登録日 2021-01-20 公開日 2022-01-26 最終更新日 2022-03-09 実験手法 ELECTRON MICROSCOPY (8.9 Å) 主引用文献 Structural Assembly of Q beta Virion and Its Diverse Forms of Virus-like Particles. Viruses, 14, 2022
7LHA	Structure of the Exo-L-galactose-6-sulfatase BuS1_11 from Bacteroides uniformis 分子名称: CALCIUM ION, Exo-L-galactose-6-sulfatase, NICKEL (II) ION 著者 Robb, C.S, Boraston, A.B. 登録日 2021-01-21 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Metabolism of a hybrid algal galactan by members of the human gut microbiome. Nat.Chem.Biol., 18, 2022
7LNP	Structure of the exo-alpha-L-galactosidase BpGH29 (D264N mutant) from Bacteroides plebeius in complex with paranitrophenyl-alpha-L-galactopyranoside 分子名称: CALCIUM ION, CHLORIDE ION, Exo-alpha-L-galactosidase, ... 著者 Boraston, A.B, Robb, C.S. 登録日 2021-02-08 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Metabolism of a hybrid algal galactan by members of the human gut microbiome. Nat.Chem.Biol., 18, 2022
7LIH	CryoEM structure of Mayaro virus icosahedral subunit 分子名称: Capsid protein, E1 protein, E2 protein 著者 Chmielewski, D, Kaelber, J.T, Jin, J, Weaver, S, Auguste, A.J, Chiu, W. 登録日 2021-01-27 公開日 2022-02-09 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Near-atomic resolution Cryo-EM structure of Mayaro virus identifies key structural determinants of alphavirus particle formation To Be Published

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