PDB: 63 件ウェブページステータス検索Chemie searchBIRD

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7MQ8	Cryo-EM structure of the human SSU processome, state pre-A1 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Vanden Broeck, A, Singh, S, Klinge, S. 登録日 2021-05-05 公開日 2021-09-22 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Nucleolar maturation of the human small subunit processome. Science, 373, 2021
7MQ9	Cryo-EM structure of the human SSU processome, state pre-A1* 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Vanden Broeck, A, Singh, S, Klinge, S. 登録日 2021-05-05 公開日 2021-09-22 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 Nucleolar maturation of the human small subunit processome. Science, 373, 2021
7MQA	Cryo-EM structure of the human SSU processome, state post-A1 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Vanden Broeck, A, Singh, S, Klinge, S. 登録日 2021-05-05 公開日 2021-09-22 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Nucleolar maturation of the human small subunit processome. Science, 373, 2021
7SE6	Crystal structure of human Fibrillarin in ligand-free state 分子名称: FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SE7	Crystal structure of human Fibrillarin in complex with S-adenosyl-L-methionine 分子名称: S-ADENOSYLMETHIONINE, rRNA 2'-O-methyltransferase fibrillarin 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SE8	Crystal structure of human Fibrillarin in complex with fragment 1 from cocktail soak 分子名称: (5S)-3-methyl-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazin-1(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SE9	Crystal structure of human Fibrillarin in complex with compound 1 from single soak 分子名称: (5S)-3-methyl-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazin-1(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SEA	Crystal structure of human Fibrillarin in complex with compound 2 from cocktail soak 分子名称: 6-(trifluoromethyl)pyrimidin-4-amine, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SEB	Crystal structure of human Fibrillarin in complex with compound 2 from single soak 分子名称: 6-(trifluoromethyl)pyrimidin-4-amine, FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SEC	Crystal structure of human Fibrillarin in complex with compound 1a 分子名称: 2-[(8S)-4-oxo-2-(trifluoromethyl)-4,5-dihydropyrazolo[1,5-a]pyrazin-6-yl]acetamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SED	Crystal structure of human Fibrillarin in complex with compound 2a 分子名称: FORMIC ACID, N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine, rRNA 2'-O-methyltransferase fibrillarin 著者 Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. 登録日 2021-09-30 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15, 2021
7SUK	Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells 分子名称: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-11-17 公開日 2022-07-06 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome. Commun Biol, 5, 2022
7XPL	Crystal structure of a C/D-free RNA-guided RNA 2'-O-methyltransferase 分子名称: BMG3 RNA strand A, BMG3 RNA strand B, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ... 著者 Wang, J, Ye, K. 登録日 2022-05-04 公開日 2022-10-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.213 Å) 主引用文献 Methylation guide RNAs without box C/D motifs. Rna, 28, 2022

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