2IMG
| Crystal structure of dual specificity protein phosphatase 23 from Homo sapiens in complex with ligand malate ion | 分子名称: | D-MALATE, Dual specificity protein phosphatase 23 | 著者 | Agarwal, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2006-10-04 | 公開日 | 2006-10-17 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex. J.Biol.Chem., 283, 2008
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2J16
| Apo & Sulphate bound forms of SDP-1 | 分子名称: | MAGNESIUM ION, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE YIL113W | 著者 | Briggs, D.C, McDonald, N.Q. | 登録日 | 2006-08-09 | 公開日 | 2007-05-22 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases. Nature, 447, 2007
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2J17
| pTyr bound form of SDP-1 | 分子名称: | MAGNESIUM ION, O-PHOSPHOTYROSINE, TYROSINE-PROTEIN PHOSPHATASE YIL113W | 著者 | Briggs, D.C, McDonald, N.Q. | 登録日 | 2006-08-09 | 公開日 | 2007-05-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases. Nature, 447, 2007
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4JNB
| Crystal structure of the Catalytic Domain of Human DUSP12 | 分子名称: | Dual specificity protein phosphatase 12, SULFATE ION | 著者 | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | 登録日 | 2013-03-15 | 公開日 | 2014-03-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4JMJ
| Structure of dusp11 | 分子名称: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | 著者 | Jeong, D.G, Kim, S.J, Ryu, S.E. | 登録日 | 2013-03-14 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4JMK
| Structure of dusp8 | 分子名称: | Dual specificity protein phosphatase 8, SULFATE ION | 著者 | Jeong, D.G, Kim, S.J, Ryu, S.E. | 登録日 | 2013-03-14 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4KI9
| Crystal structure of the catalytic domain of human DUSP12 at 2.0 A resolution | 分子名称: | Dual specificity protein phosphatase 12, PHOSPHATE ION | 著者 | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | 登録日 | 2013-05-02 | 公開日 | 2014-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The family-wide structure and function of human dual-specificity protein phosphatases Acta Crystallogr.,Sect.D, 70, 2014
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4KYQ
| Structure of a product bound plant phosphatase | 分子名称: | CITRATE ANION, Phosphoglucan phosphatase LSF2, chloroplastic | 著者 | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | 登録日 | 2013-05-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation. Plant Cell, 25, 2013
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4KYR
| Structure of a product bound plant phosphatase | 分子名称: | PHOSPHATE ION, Phosphoglucan phosphatase LSF2, chloroplastic, ... | 著者 | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | 登録日 | 2013-05-29 | 公開日 | 2013-07-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation. Plant Cell, 25, 2013
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5XJV
| Two intermediate states of conformation switch in dual specificity phosphatase 13a | 分子名称: | Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION | 著者 | Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. | 登録日 | 2017-05-04 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Two intermediate states of the conformational switch in dual specificity phosphatase 13a Pharmacol. Res., 128, 2018
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5Y15
| Crystal structure of human DUSP28 | 分子名称: | Dual specificity phosphatase 28, PHOSPHATE ION | 著者 | Ku, B, Hong, W, Kim, S.J, Ryu, S.E. | 登録日 | 2017-07-19 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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5Y16
| Crystal structure of human DUSP28(Y102H) | 分子名称: | CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION | 著者 | Ku, B, Kim, M, Kim, S.J, Ryu, S.E. | 登録日 | 2017-07-19 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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5Z59
| Crystal structure of Tk-PTP in the inactive form | 分子名称: | Protein-tyrosine phosphatase | 著者 | Ku, B, Yun, H.Y, Kim, S.J. | 登録日 | 2018-01-17 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | 主引用文献 | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5Z5B
| Crystal structure of Tk-PTP in the G95A mutant form | 分子名称: | CHLORIDE ION, FORMIC ACID, Protein-tyrosine phosphatase | 著者 | Ku, B, Yun, H.Y, Kim, S.J. | 登録日 | 2018-01-17 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5Z5A
| Crystal structure of Tk-PTP in the active form | 分子名称: | Protein-tyrosine phosphatase, VANADATE ION | 著者 | Ku, B, Yun, H.Y, Kim, S.J. | 登録日 | 2018-01-17 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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1VHR
| HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, SULFATE ION | 著者 | Yuvaniyama, J, Denu, J.M, Dixon, J.E, Saper, M.A. | 登録日 | 1996-02-20 | 公開日 | 1996-06-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the dual specificity protein phosphatase VHR. Science, 272, 1996
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6L1S
| Crystal structure of DUSP22 mutant_C88S | 分子名称: | Dual specificity protein phosphatase 22, PHOSPHATE ION | 著者 | Lai, C.H, Chang, C.C, Lyu, P.C. | 登録日 | 2019-09-30 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.3611 Å) | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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1WRM
| Crystal structure of JSP-1 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, dual specificity phosphatase 22 | 著者 | Yokota, T, Kashima, A, Kato, R, Sugio, S. | 登録日 | 2004-10-22 | 公開日 | 2005-10-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution Proteins, 66, 2006
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6LMY
| Crystal structure of DUSP22 mutant_C88S/S93A | 分子名称: | Dual specificity protein phosphatase 22, PHOSPHATE ION | 著者 | Lai, C.H, Lyu, P.C. | 登録日 | 2019-12-27 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LOT
| Crystal structure of DUSP22 mutant_N128D | 分子名称: | Dual specificity protein phosphatase 22, SULFATE ION | 著者 | Lai, C.H, Lyu, P.C. | 登録日 | 2020-01-07 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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1X24
| Prl-1 (ptp4a) | 分子名称: | protein tyrosine phosphatase 4a1 | 著者 | Zhang, Z.Y, Sun, J.P, Liu, S, Wang, W.Q, Yang, H. | 登録日 | 2005-04-20 | 公開日 | 2005-10-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion(,) Biochemistry, 44, 2005
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6LVQ
| Crystal structure of DUSP22_VO4 | 分子名称: | Dual specificity protein phosphatase 22, VANADATE ION | 著者 | Lai, C.H, Lyu, P.C. | 登録日 | 2020-02-04 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LOU
| Crystal structure of DUSP22 mutant_C88S/S93N | 分子名称: | Dual specificity protein phosphatase 22, PHOSPHATE ION | 著者 | Lai, C.H, Lyu, P.C. | 登録日 | 2020-01-07 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5301 Å) | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6MC1
| Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-(methylthio)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3,3-dimethyl-1-{[9-(methylsulfanyl)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one, ACETATE ION, ... | 著者 | Gannam, Z.T.K, Anderson, K.S, Bennett, A.M, Lolis, E. | 登録日 | 2018-08-30 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | An allosteric site on MKP5 reveals a strategy for small-molecule inhibition. Sci.Signal., 13, 2020
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1XM2
| Crystal structure of Human PRL-1 | 分子名称: | SULFATE ION, Tyrosine Phosphatase | 著者 | Jeong, D.G, Kim, S.J, Kim, J.H, Son, J.H, Ryu, S.E. | 登録日 | 2004-10-01 | 公開日 | 2005-01-25 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms J.Mol.Biol., 345, 2005
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