PDB: 56 件ウェブページステータス検索Chemie searchBIRD

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7O9T	Crystal structure of Human Menin in apo form 分子名称: 1,2-ETHANEDIOL, Menin 著者 Groves, M.R, Gao, K. 登録日 2021-04-17 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.159 Å) 主引用文献 Crystal structure of Human Menin in apo form To Be Published
7O9X	Crystal structure of Human Menin with fragment 16 分子名称: (2-methoxyphenyl)methanamine, 1,2-ETHANEDIOL, GLYCEROL, ... 著者 Groves, M.R, Gao, K. 登録日 2021-04-17 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.299 Å) 主引用文献 Crystal structure of Human Menin with fragment 16 To Be Published
7O9Z	Crystal structure of Human Menin in complex with BD-08 分子名称: (~{E})-2-cyano-3-(2~{H}-indazol-6-yl)-~{N}-(2-morpholin-4-ylethyl)prop-2-enamide, 1,2-ETHANEDIOL, GLYCEROL, ... 著者 Groves, M.R, Gao, K. 登録日 2021-04-18 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Crystal structure of Human Menin in complex with BD-08 To Be Published
6BXY	Menin in complex with MI-1481 分子名称: 1,2-ETHANEDIOL, 4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DIMETHYL SULFOXIDE, ... 著者 Borkin, D, Klossowski, S, Pollock, J, Linhares, B, Cierpicki, T, Grembecka, J. 登録日 2017-12-19 公開日 2018-11-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction. J.Med.Chem., 61, 2018
4FXX	Structure of SF1 coiled-coil domain 分子名称: IMIDAZOLE, MALONATE ION, Splicing factor 1 著者 Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L. 登録日 2012-07-03 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4801 Å) 主引用文献 Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
4FXW	Structure of phosphorylated SF1 complex with U2AF65-UHM domain 分子名称: SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit 著者 Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. 登録日 2012-07-03 公開日 2013-01-16 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013

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