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1L17	HYDROPHOBIC STABILIZATION IN T4 LYSOZYME DETERMINED DIRECTLY BY MULTIPLE SUBSTITUTIONS OF ILE 3 分子名称: T4 LYSOZYME 著者 Matsumura, M, Dao-Pin, S, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3. Nature, 334, 1988
1L45	CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991
1L79	DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Hurley, J.H, Matthews, B.W. 登録日 1991-11-12 公開日 1993-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme. J.Mol.Biol., 224, 1992
1L55	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991
1L84	A CAVITY-CONTAINING MUTANT OF T4 LYSOZYME IS STABILIZED BY BURIED BENZENE 分子名称: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Eriksson, A.E, Matthews, B.W. 登録日 1992-01-21 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene. Nature, 355, 1992
1L69	MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Zhang, X, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992
1L85	SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Eriksson, A.E, Matthews, B.W. 登録日 1992-01-21 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences. J.Mol.Biol., 229, 1993
1LGU	T4 Lysozyme Mutant L99A/M102Q 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme 著者 Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. 登録日 2002-04-16 公開日 2002-05-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Model Binding Site for Testing Scoring Functions in Molecular Docking J.Mol.Biol., 322, 2002
1L12	CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME 分子名称: T4 LYSOZYME 著者 Dao-Pin, S, Alber, T, Matthews, B.W. 登録日 1988-02-05 公開日 1988-04-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987
1L16	STRUCTURAL ANALYSIS OF THE TEMPERATURE-SENSITIVE MUTANT OF BACTERIOPHAGE T4 LYSOZYME, GLYCINE 156 (RIGHT ARROW) ASPARTIC ACID 分子名称: T4 LYSOZYME 著者 Gray, T.M, Matthews, B.W. 登録日 1988-02-05 公開日 1988-04-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural analysis of the temperature-sensitive mutant of bacteriophage T4 lysozyme, glycine 156----aspartic acid. J.Biol.Chem., 262, 1987
1L24	ENHANCED PROTEIN THERMOSTABILITY FROM SITE-DIRECTED MUTATIONS THAT DECREASE THE ENTROPY OF UNFOLDING 分子名称: T4 LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding. Proc.Natl.Acad.Sci.USA, 84, 1987
1L34	HIGH-RESOLUTION STRUCTURE OF THE TEMPERATURE-SENSITIVE MUTANT OF PHAGE LYSOZYME, ARG 96 (RIGHT ARROW) HIS 分子名称: T4 LYSOZYME 著者 Weaver, L.H, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-resolution structure of the temperature-sensitive mutant of phage lysozyme, Arg 96----His. Biochemistry, 28, 1989
1L41	CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991
1L48	STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2022-11-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991
1L51	STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991
1L03	CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME 著者 Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W. 登録日 1988-02-05 公開日 1988-04-16 最終更新日 2022-11-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987
1L60	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: T4 LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers, 32, 1992
1L67	TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Heinz, D, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc.Natl.Acad.Sci.USA, 89, 1992
1L0J	METHIONINE CORE MUTANT OF T4 LYSOZYME 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME 著者 Gassner, N.C, Baase, W.A, Mooers, B.H, Busam, R.D, Weaver, L.H, Lindstrom, J.D, Quillin, M.L, Matthews, B.W. 登録日 2002-02-11 公開日 2003-06-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability BIOPHYS.CHEM., 100, 2003
1L18	HYDROPHOBIC STABILIZATION IN T4 LYSOZYME DETERMINED DIRECTLY BY MULTIPLE SUBSTITUTIONS OF ILE 3 分子名称: T4 LYSOZYME 著者 Matsumura, M, Dao-Pin, S, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3. Nature, 334, 1988
1L74	MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Zhang, X, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992
1L94	SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Eriksson, A.E, Matthews, B.W. 登録日 1992-01-21 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences. J.Mol.Biol., 229, 1993
1L32	REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY 分子名称: T4 LYSOZYME 著者 Bell, J.A, Dao-Pin, S, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability. Science, 239, 1988
1L37	CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991
1L56	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers, 32, 1992

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