PDB: 82129 件ウェブページステータス検索Chemie searchBIRD

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8CPP	CRYSTAL STRUCTURES OF CYTOCHROME P450-CAM COMPLEXED WITH CAMPHANE, THIOCAMPHOR, AND ADAMANTANE: FACTORS CONTROLLING P450 SUBSTRATE HYDROXYLATION 分子名称: CYTOCHROME P450CAM, PROTOPORPHYRIN IX CONTAINING FE, THIOCAMPHOR 著者 Raag, R, Poulos, T.L. 登録日 1990-05-18 公開日 1991-07-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of cytochrome P-450CAM complexed with camphane, thiocamphor, and adamantane: factors controlling P-450 substrate hydroxylation. Biochemistry, 30, 1991
8CPL	YZw2 a scaffold for cryo-EM of small proteins of interest 分子名称: PYRIDOXAL-5'-PHOSPHATE, Putrescine aminotransferase,Immunoglobulin G-binding protein A 著者 Moche, M, Friberg, O, Nygren, P.A, Nilvebrant, J. 登録日 2023-03-03 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.605 Å) 主引用文献 Engineered imaging scaffolds for cryo-EM of small proteins of interest. To Be Published
8CPK	Crystal structure of EtpA secretion domain from Enterotoxigenic Escherichia coli 分子名称: EtpA 著者 Ntui, C.M, Schubert, W.D, Fleckenstein, J.M. 登録日 2023-03-02 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 EtpA secretion domain To Be Published
8CPD	Cryo-EM structure of CRaf dimer with 14:3:3 分子名称: 14-3-3 protein zeta isoform X1, RAF proto-oncogene serine/threonine-protein kinase 著者 Dedden, D, Graedler, U, Schwarz, D, Thomsen, M, Leuthner, B, Schneider, E, Nitsche, J. 登録日 2023-03-02 公開日 2024-02-21 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes. J.Mol.Biol., 436, 2024
8CPB	1,6-anhydro-n-actetylmuramic acid kinase (AnmK) in complex with AMPPNP, and AnhMurNAc at 1.7 Angstroms resolution. 分子名称: 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, Anhydro-N-acetylmuramic acid kinase, GLYCEROL, ... 著者 Jimenez-Faraco, E, Hermoso, J.A. 登録日 2023-03-02 公開日 2023-09-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa. J.Biol.Chem., 299, 2023
8CPA	COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY 分子名称: CARBOXYPEPTIDASE A, O-(((1R)-((N-(PHENYL-METHOXY-CARBONYL)-ALANYL)-AMINO)METHYL)HYDROXYPHOSPHINYL)3-L-PHENYLLACTATE, ZINC ION 著者 Kim, H, Lipscomb, W.N. 登録日 1991-05-21 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Comparison of the structures of three carboxypeptidase A-phosphonate complexes determined by X-ray crystallography. Biochemistry, 30, 1991
8CP6	Type six secretion system exported effector 5 (Tse5) 分子名称: Toxin protein Tse5 著者 Gonzalez-Magana, A, Tascon, I, Ubarretxena-Belandia, I, Albesa-Jove, D. 登録日 2023-03-01 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane. Nat Commun, 14, 2023
8CP5	Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and Sulphate 分子名称: DI(HYDROXYETHYL)ETHER, FAD-binding protein, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Rotilio, L, Mattevi, A. 登録日 2023-03-01 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center. J.Biol.Chem., 299, 2023
8CP4	[4Fe-4S] cluster containing LarE in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, IRON/SULFUR CLUSTER, ... 著者 Zecchin, P, Pecqueur, L, Golinelli-Pimpaneau, B. 登録日 2023-03-01 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024
8CP3	Apo-LarE in complex with AMP-PNP 分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, NAD_synthase domain-containing protein, ... 著者 Zecchin, P, Pecqueur, L, Golinelli-Pimpaneau, B. 登録日 2023-03-01 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024
8CP2	Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and L-aspartate 分子名称: 3-NITROPROPANOIC ACID, ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Rotilio, L, Mattevi, A. 登録日 2023-03-01 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center. J.Biol.Chem., 299, 2023
8CP0	Structure of the catalytic domain of P. vivax Sub1 (trigonal crystal form) 分子名称: CALCIUM ION, subtilisin 著者 Martinez, M, Bouillon, A, Batista, F, Alzari, P.M, Barale, J.C, Haouz, A. 登録日 2023-03-01 公開日 2023-07-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.251 Å) 主引用文献 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived alpha-ketoamide inhibitor. Acta Crystallogr D Struct Biol, 79, 2023
8COZ	Structure of the catalytic domain of P. vivax Sub1 (triclinic crystal form) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SULFATE ION, ... 著者 Martinez, M, Bouillon, A, Batista, F, Alzari, P.M, Barale, J.C, Haouz, A. 登録日 2023-03-01 公開日 2023-07-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.438 Å) 主引用文献 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived alpha-ketoamide inhibitor. Acta Crystallogr D Struct Biol, 79, 2023
8COY	Structure of the catalytic domain of P. vivax Sub1 (triclinic crystal form) in complex with inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SULFATE ION, ... 著者 Martinez, M, Bouillon, A, Batista, F, Alzari, P.M, Barale, J.C, Haouz, A. 登録日 2023-03-01 公開日 2023-07-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.507 Å) 主引用文献 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived alpha-ketoamide inhibitor. Acta Crystallogr D Struct Biol, 79, 2023
8COV	Pa.FabF-C164Q in complex with 6-chloro-2-methyl-1H-indole-5-carboxylic acid 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, 6-chloranyl-2-methyl-1~{H}-indole-5-carboxylic acid, DIMETHYL SULFOXIDE, ... 著者 Georgiou, C, Brenk, R, Espeland, L.O. 登録日 2023-02-28 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
8COU	Pa.FabF-C164Q in complex with 3-acetamido-4-methoxybenzoic acid 分子名称: 3-acetamido-4-methoxy-benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ... 著者 Georgiou, C, Brenk, R. 登録日 2023-02-28 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
8COP	Mycobacterium tuberculosis dihydrofolate reductase in complex with N-(4-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)phenyl)methanesulfonamide 分子名称: COBALT (II) ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Kirkman, T.J, Dias, M.V.B. 登録日 2023-02-28 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Expansion of a series of pyrimidine derivatives utilising fragment-based merging showcasing anleads to increased affinity with to Mycobacterium tuberculosis dihydrofolate reductase To Be Published
8COM	Structure of the Nucleosome Core Particle from Trypanosoma brucei 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Burdett, H, Deak, G, Wilson, M.D. 登録日 2023-02-28 公開日 2023-07-12 最終更新日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Histone divergence in trypanosomes results in unique alterations to nucleosome structure. Nucleic Acids Res., 51, 2023
8COK	Structural analysis of ING3 protein and its binding to histone H3 分子名称: Inhibitor of growth protein 3 著者 Ferreras-Gutierrez, M, Medrano, F.J, Blanco, F.J. 登録日 2023-02-28 公開日 2023-05-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structural analysis of ING3 protein and histone H3 binding. Int.J.Biol.Macromol., 242, 2023
8COI	Human adenovirus-derived synthetic ADDobody binder 分子名称: ADDobody 著者 Buzas, D, Toelzer, C, Gupta, K, Berger-Schaffitzel, C, Berger, I. 登録日 2023-02-28 公開日 2023-12-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders. Structure, 32, 2024
8COH	Structure of the complement C5 specific nanobody TPP-3444 分子名称: CITRIC ACID, MANGANESE (II) ION, Nanobody TPP-3444 著者 Pedersen, D.V, Andersen, G.R. 登録日 2023-02-28 公開日 2024-01-03 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration. Mol.Immunol., 165, 2023
8CO5	The surface-engineered photosensory module (PAS-GAF-PHY) of the bacterial phytochrome Agp1 (AtBphP1) in the Pr form with parallel dimer formation 分子名称: 3-[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-2-[[5-[(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Bacteriophytochrome protein, MAGNESIUM ION 著者 Schmidt, A, Sauthof, L, Krauss, N, Scheerer, P. 登録日 2023-02-27 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structures of a bacterial phytochrome exhibiting a group-subgroup relationship reveal pronounced flexibility of the photosensory core module in the Pr state To Be Published
8CO2	YdaS N-terminal domain from prophage CP-933P in E. coli O157:H7 分子名称: ISOPROPYL ALCOHOL, Putative antirepressor protein Cro, SULFATE ION 著者 Prolic-Kalinsek, M, Loris, R. 登録日 2023-02-26 公開日 2023-03-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.63880718 Å) 主引用文献 YdaS from the Escherichia coli cryptic prophage CP-933P forms an evolutionary link between Cro repressors and HigA antitoxins To Be Published
8CO0	Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide 分子名称: 5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide, Carbonic anhydrase 9, GLYCEROL, ... 著者 Leitans, J, Tars, K. 登録日 2023-02-25 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect. J.Med.Chem., 66, 2023
8CNZ	mmLarE-[4Fe-4S] phased by Fe-SAD 分子名称: CHLORIDE ION, IODIDE ION, IRON/SULFUR CLUSTER, ... 著者 Pecqueur, L, Zecchin, P, Golinelli-Pimpaneau, B. 登録日 2023-02-24 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024

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