7JGY
| |
6PRW
| |
6PWH
| |
6OH1
| IgA1 Protease G5 domain structure | 分子名称: | Immunoglobulin A1 protease | 著者 | Eisenmesser, E.Z, Chi, Y.C, Paukovich, N, Redzic, J.S, Rahkola, J.T, Janoff, E.N. | 登録日 | 2019-04-04 | 公開日 | 2020-02-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Streptococcus pneumoniae G5 domains bind different ligands. Protein Sci., 28, 2019
|
|
7JGX
| |
7JHF
| |
7KQV
| |
7KRG
| |
6LXT
| Structure of post fusion core of 2019-nCoV S2 subunit | 分子名称: | Spike protein S2, TETRAETHYLENE GLYCOL, ZINC ION | 著者 | Zhu, Y, Sun, F. | 登録日 | 2020-02-11 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Res., 30, 2020
|
|
7LXA
| T4 lysozyme mutant L99A | 分子名称: | (2-methylprop-2-en-1-yl)benzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... | 著者 | Kamenik, A.S, Singh, I, Lak, P, Balius, T.E, Liedl, K.R, Shoichet, B.K. | 登録日 | 2021-03-03 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Energy penalties enhance flexible receptor docking in a model cavity. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7LOG
| T4 lysozyme mutant L99A in complex with 3-butylpyridine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-butylpyridine, BETA-MERCAPTOETHANOL, ... | 著者 | Kamenik, A.S, Singh, I, Lak, P, Balius, T.E, Liedl, K.R, Shoichet, B.K. | 登録日 | 2021-02-10 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | 主引用文献 | Energy penalties enhance flexible receptor docking in a model cavity. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
2C2T
| Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-((7,8-dicarbaundecaboran-7-yl)methyl)-6-methylpyrimidine, a novel boron containing, nonclassical Antifolate | 分子名称: | (S)-2,4-DIAMINO-5-((7,8-DICARBAUNDECABORAN-7-YL)METHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ... | 著者 | leung, A.K.W, reynolds, R.C, riordan, J.M, borhani, D.W. | 登録日 | 2005-09-30 | 公開日 | 2007-04-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation. J.Med.Chem., 50, 2007
|
|
2BKJ
| |
6MXR
| |
6MQF
| |
7M96
| Bovine sigma-2 receptor bound to Z4857158944 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-({[(1S)-1-hydroxy-2-methyl-1-phenylpropan-2-yl]amino}methyl)-1-methyl-3,4-dihydroquinolin-2(1H)-one, ... | 著者 | Alon, A, Kruse, A.C. | 登録日 | 2021-03-30 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structures of the sigma 2 receptor enable docking for bioactive ligand discovery. Nature, 600, 2021
|
|
7M95
| Bovine sigma-2 receptor bound to Z1241145220 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[1-(3-phenylpropyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine, CHOLESTEROL, ... | 著者 | Alon, A, Kruse, A.C. | 登録日 | 2021-03-30 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structures of the sigma 2 receptor enable docking for bioactive ligand discovery. Nature, 600, 2021
|
|
7MFI
| Bovine sigma-2 receptor bound to cholesterol | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHOLESTEROL, ... | 著者 | Alon, A, Kruse, A.C. | 登録日 | 2021-04-09 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structures of the sigma 2 receptor enable docking for bioactive ligand discovery. Nature, 600, 2021
|
|
7M94
| Bovine sigma-2 receptor bound to Roluperidone | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Roluperidone, Sigma intracellular receptor 2 | 著者 | Alon, A, Kruse, A.C. | 登録日 | 2021-03-30 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structures of the sigma 2 receptor enable docking for bioactive ligand discovery. Nature, 600, 2021
|
|
7M93
| Bovine sigma-2 receptor bound to PB28 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PB28, Sigma intracellular receptor 2 | 著者 | Alon, A, Kruse, A.C. | 登録日 | 2021-03-30 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Structures of the sigma 2 receptor enable docking for bioactive ligand discovery. Nature, 600, 2021
|
|
6MY4
| Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR] | 分子名称: | 1,2-ETHANEDIOL, anti-VEGF-A Fab fragment bH1 heavy chain, anti-VEGF-A Fab fragment bH1 light chain | 著者 | Shi, R, Picard, M.-E, Manenda, M. | 登録日 | 2018-11-01 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Binding symmetry and surface flexibility mediate antibody self-association. Mabs, 11, 2019
|
|
6MQD
| Myotoxin II from Bothrops moojeni complexed with Rosmarinic Acid | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, Basic phospholipase A2 homolog 2 | 著者 | Salvador, G.H.M, Fontes, M.R.M. | 登録日 | 2018-10-09 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches. Sci Rep, 9, 2019
|
|
7N0R
| |
7N0I
| |
2E3E
| |