PDB: 8267 件ウェブページステータス検索Chemie searchBIRD

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7NVW	TFIIH in a pre-translocated state (without ADP-BeF3) 分子名称: CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription factor IIE subunit 1, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
5MDT	Structure of the CTD-interacting domain (CID) of Seb1 from S. pombe. 分子名称: Rpb7-binding protein seb1 著者 Wittmann, S, Renner, M, Vasiljeva, L, Grimes, J. 登録日 2016-11-13 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun, 8, 2017
1YV2	Hepatitis C virus NS5B RNA-dependent RNA Polymerase genotype 2a 分子名称: GLYCEROL, RNA dependent RNA polymerase, SULFATE ION 著者 Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. 登録日 2005-02-14 公開日 2005-03-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors J.Biol.Chem., 280, 2005
1S0V	Structural basis for substrate selection by T7 RNA polymerase 分子名称: 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ... 著者 Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-01-05 公開日 2004-02-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate selection by t7 RNA polymerase. Cell(Cambridge,Mass.), 116, 2004
5OHQ	Crystal structure of the KOW6-KOW7 domain of human DSIF 分子名称: CHLORIDE ION, SODIUM ION, Transcription elongation factor SPT5 著者 Bernecky, C, Plitzko, J.M, Cramer, P. 登録日 2017-07-17 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.098 Å) 主引用文献 Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
1YVZ	Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor 分子名称: 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION 著者 Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. 登録日 2005-02-16 公開日 2005-03-22 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
1YVX	Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor 分子名称: 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION 著者 Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. 登録日 2005-02-16 公開日 2005-03-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
7JV7	Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex 分子名称: CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ... 著者 Xie, Y, Ren, Y. 登録日 2020-08-20 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.850553 Å) 主引用文献 Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
7NVV	XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, General transcription and DNA repair factor IIH helicase subunit XPB, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
4Q5S	Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3'), ... 著者 Murakami, K.S. 登録日 2014-04-17 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme. J.Biol.Chem., 289, 2014
2LO6	Structure of Nrd1 CID bound to phosphorylated RNAP II CTD 分子名称: DNA-directed RNA polymerase II subunit RPB1, Protein NRD1 著者 Kubicek, K, Cerna, H, Pasulka, J, Holub, P, Hrossova, D, Loehr, F, Hofr, C, Vanacova, S, Stefl, R. 登録日 2012-01-17 公開日 2012-12-26 実験手法 SOLUTION NMR 主引用文献 Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. Genes Dev., 26, 2012
3OMX	Crystal structure of Ssu72 with vanadate complex 分子名称: CG14216, VANADATE ION 著者 Zhang, Y, Zhang, M, Zhang, Y. 登録日 2010-08-27 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3366 Å) 主引用文献 Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem.J., 434, 2011
2RF4	Crystal structure of the RNA Polymerase I subcomplex A14/43 分子名称: DNA-directed RNA polymerase I subunit RPA4 著者 Geiger, S.R, Kuhn, C.D, Cramer, P. 登録日 2007-09-28 公開日 2008-01-15 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Functional architecture of RNA polymerase I. Cell(Cambridge,Mass.), 131, 2007
2A69	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2A68	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-01 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
8JLD	Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail 分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-02 公開日 2023-10-04 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
8JL9	Cryo-EM structure of the human nucleosome with scFv 分子名称: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-02 公開日 2023-10-04 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
8JLB	Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant 分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-02 公開日 2023-10-04 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (2.36 Å) 主引用文献 Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
3FDF	Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Orthorhombic crystal form. Northeast Structural Genomics Consortium target FR253. 分子名称: FR253 著者 Kuzin, A.P, Chen, Y, Seetharaman, J, Forouhar, F, Chinag, Y, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2008-11-25 公開日 2009-01-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Orthorombic crystal structure of serine phosphatase of rna polymerase ii ctd from fly drosofila melanogaster. northeast structural genomics consortium target fr253. To be Published
8JLA	Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 分子名称: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-02 公開日 2023-10-04 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.44 Å) 主引用文献 Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
5HCN	GPN-loop GTPase Npa3 in complex with GMPPCP 分子名称: GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... 著者 Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. 登録日 2016-01-04 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
5HCI	GPN-loop GTPase Npa3 in complex with GDP 分子名称: GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. 登録日 2016-01-04 公開日 2016-01-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
6IZX	The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678 分子名称: 2-oxo-2H-1,3-benzoxathiol-5-yl acetate, COBALT (II) ION, Genome polyprotein, ... 著者 Shimizu, H, Sekine, S. 登録日 2018-12-20 公開日 2019-12-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase. Plos Negl Trop Dis, 13, 2019
6IZY	The RNA-dependent RNA polymerase domain of dengue 2 NS5 分子名称: COBALT (II) ION, Genome polyprotein, ZINC ION 著者 Shimizu, H, Sekine, S. 登録日 2018-12-20 公開日 2019-12-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase. Plos Negl Trop Dis, 13, 2019
2F8E	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein 分子名称: MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-12-02 公開日 2006-03-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006

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