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4Q96
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BU of 4q96 by Molmil
CID of human RPRD1B in complex with an unmodified CTD peptide
分子名称: RPB1-CTD, Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, ...
著者Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC)
登録日2014-04-29
公開日2014-06-04
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
4Q94
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BU of 4q94 by Molmil
human RPRD1B CID in complex with a RPB1-CTD derived Ser2 phosphorylated peptide
分子名称: Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, UNKNOWN ATOM OR ION, ...
著者Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC)
登録日2014-04-29
公開日2014-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
4FLA
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BU of 4fla by Molmil
Crystal structure of human RPRD1B, carboxy-terminal domain
分子名称: Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION
著者Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC)
登録日2012-06-14
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
3NFG
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BU of 3nfg by Molmil
Crystal structure of Dimerization module of RNA polymerase I subcomplex A49/A34.5
分子名称: DNA-directed RNA polymerase I subunit RPA34, DNA-directed RNA polymerase I subunit RPA49
著者Geiger, S.R.
登録日2010-06-10
公開日2010-09-08
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
1ONV
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BU of 1onv by Molmil
NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1
分子名称: Transcription initiation factor IIF, alpha subunit, serine phosphatase FCP1a
著者Nguyen, B.D, Abbott, K.L, Potempa, K, Kobor, M.S, Archambault, J, Greenblatt, J, Legault, P, Omichinski, J.G.
登録日2003-03-02
公開日2003-05-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1
Proc.Natl.Acad.Sci.USA, 100, 2003
3NFH
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BU of 3nfh by Molmil
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)
分子名称: DNA-directed RNA polymerase I subunit RPA49
著者Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
登録日2010-06-10
公開日2010-09-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFI
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BU of 3nfi by Molmil
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DNA-directed RNA polymerase I subunit RPA49
著者Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
登録日2010-06-10
公開日2010-09-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
1GX6
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BU of 1gx6 by Molmil
Hepatitis C Virus RNA polymerase in complex with UTP and manganese
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE, URIDINE 5'-TRIPHOSPHATE
著者Bressanelli, S, Rey, F.A.
登録日2002-03-27
公開日2002-04-10
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
1GX5
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BU of 1gx5 by Molmil
Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Bressanelli, S, Rey, F.A.
登録日2002-03-27
公開日2002-04-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
4QJF
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BU of 4qjf by Molmil
X-ray crystal structure of Thermocuccus kodakarensis RNA polymerase Rpp4/Rpo7 (RpoF/RpoE) complex
分子名称: DNA-directed RNA polymerase, subunit E', subunit F
著者Murakami, K.S.
登録日2014-06-03
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.312 Å)
主引用文献Crystal structure of euryarchaeal RNA polymerase and insight into the evolution of RNA polymerase II structure
Nat.Commun., 2014
3S1M
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BU of 3s1m by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1)
分子名称: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
登録日2011-05-15
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Initiation complex structure and promoter proofreading.
Science, 333, 2011
6YYS
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BU of 6yys by Molmil
Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State II, primary channel engaged and active site interfering
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Kouba, T, Koval, T, Krasny, L, Dohnalek, J.
登録日2020-05-05
公開日2020-11-04
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase.
Nat Commun, 11, 2020
6F5P
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BU of 6f5p by Molmil
A mechanism for the activation of the influenza virus transcriptase
分子名称: ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, DNA-directed RNA polymerase subunit, MAGNESIUM ION, ...
著者Serna Martin, I, Grimes, J.M.
登録日2017-12-02
公開日2018-09-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4.14 Å)
主引用文献A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
6F5O
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BU of 6f5o by Molmil
A mechanism for the activation of the influenza virus transcriptase
分子名称: 3' promoter vRNA, 5' promoter vRNA, Polymerase acidic protein, ...
著者Serna Martin, I, Grimes, J.M.
登録日2017-12-02
公開日2018-06-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-14
公開日2023-05-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-20
公開日2023-05-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
9EGY
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BU of 9egy by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Markert, J, Farnung, L.
登録日2024-11-21
公開日2024-12-18
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EGX
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BU of 9egx by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Markert, J, Farnung, L.
登録日2024-11-21
公開日2024-12-18
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EGZ
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BU of 9egz by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, bp +27
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Markert, J.W, Farnung, L.
登録日2024-11-21
公開日2024-12-18
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EH0
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BU of 9eh0 by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 30 bp upstream
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Markert, J, Farnung, L.
登録日2024-11-21
公開日2024-12-18
最終更新日2025-02-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EH2
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BU of 9eh2 by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Markert, J, Farnung, L.
登録日2024-11-21
公開日2024-12-18
最終更新日2025-02-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
7NKX
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BU of 7nkx by Molmil
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-08-25
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
9EH1
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BU of 9eh1 by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 20 bp upstream
分子名称: DNA-directed RNA polymerase I, II, and III subunit RPABC5, ...
著者Markert, J, Farnung, L.
登録日2024-11-21
公開日2024-12-18
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025

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件を2025-07-09に公開中

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