1YUY
 
 | | HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2a | | 分子名称: | RNA-Dependent RNA polymerase, SULFATE ION | | 著者 | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | | 登録日 | 2005-02-14 | | 公開日 | 2005-03-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
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3TJ1
 | | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | | 分子名称: | RNA polymerase I-specific transcription initiation factor RRN3 | | 著者 | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | | 登録日 | 2011-08-23 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
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3P9Y
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8JCH
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6TED
 | | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | | 分子名称: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | | 著者 | Vos, S.M, Farnung, L, Cramer, P. | | 登録日 | 2019-11-11 | | 公開日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
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8W8E
 | | human co-transcriptional RNA capping enzyme RNGTT | | 分子名称: | DNA (36-MER), DNA (45-MER), DNA-directed RNA polymerase II subunit E, ... | | 著者 | Li, Y, Wang, Q, Xu, Y, Li, Z. | | 登録日 | 2023-09-02 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of co-transcriptional RNA capping enzymes on paused transcription complex.
Nat Commun, 15, 2024
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8W8F
 | | human co-transcriptional RNA capping enzyme RNGTT-CMTR1 | | 分子名称: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (36-MER), DNA (45-MER), ... | | 著者 | Li, Y, Wang, Q, Xu, Y, Li, Z. | | 登録日 | 2023-09-02 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of co-transcriptional RNA capping enzymes on paused transcription complex.
Nat Commun, 15, 2024
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6IRY
 | | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH | | 分子名称: | 1,2-ETHANEDIOL, PDX1 C-terminal-inhibiting factor 1, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2018-11-14 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
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6IRX
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8JL9
 | | Cryo-EM structure of the human nucleosome with scFv | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
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8JLB
 | | Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
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8JLD
 | | Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
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8JLA
 | | Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
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6GMH
 | | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | | 分子名称: | CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... | | 著者 | Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. | | 登録日 | 2018-05-26 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
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8K5P
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7ZSB
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7ZSA
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7ZS9
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6GML
 | | Structure of paused transcription complex Pol II-DSIF-NELF | | 分子名称: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | | 登録日 | 2018-05-27 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
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5U5Q
 | | 12 Subunit RNA Polymerase II at Room Temperature collected using SFX | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A. | | 登録日 | 2016-12-07 | | 公開日 | 2017-03-29 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep, 7, 2017
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4WQS
 | | Thermus thermophilus RNA polymerase backtracked complex | | 分子名称: | DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Murayama, Y, Sekine, S, Yokoyama, S. | | 登録日 | 2014-10-22 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (4.306 Å) | | 主引用文献 | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
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4WZM
 | | Mutant K18E of RNA dependent RNA polymerase from Foot-and-Mouth Disease Virus complexed with RNA | | 分子名称: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Verdaguer, N, Ferrer-Orta, C, de la Higuera, N. | | 登録日 | 2014-11-20 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
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4WZQ
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7EU0
 | | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | | 分子名称: | DNA (33-MER), DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase IV subunit 1, ... | | 著者 | Fang, C.L, Wu, X.X, Huang, K, Zhang, Y. | | 登録日 | 2021-05-15 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
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7EU1
 | | The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme | | 分子名称: | DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerases II and IV subunit 5A, DNA-directed RNA polymerases II, ... | | 著者 | Fang, C.L, Wu, X.X, Huang, K, Zhang, Y. | | 登録日 | 2021-05-15 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
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