PDB: 1712 件ウェブページステータス検索Chemie searchBIRD

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6WS0	Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT 分子名称: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B 著者 McPherson, K.S, Korzhnev, D.M. 登録日 2020-04-30 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis. Chemmedchem, 16, 2021
2EHW	Conserved hypothetical proteim (TTHB059) from Thermo thermophilus HB8 分子名称: Hypothetical protein TTHB059 著者 Rehse, P.H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-09 公開日 2007-09-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Conserved hypothetical proteim (TTHB059) from Thermo thermophilus HB8 To be Published
2EXC	Inhibitor complex of JNK3 分子名称: Mitogen-activated protein kinase 10, N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE 著者 Xue, Y. 登録日 2005-11-08 公開日 2006-11-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Inhibitor complex of JNK3 To be Published
2DPW	Hpothetical Transferase Structure from Thermus thermophilus 分子名称: Hypothetical protein TTHA0179, SODIUM ION 著者 Rehse, P.H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-05-17 公開日 2007-05-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Hypothetical Transferase from Thermus thermophilus To be Published
1U2U	Nmr solution structure of a designed heterodimeric leucine zipper 分子名称: General control protein GCN4 著者 Marti, D.N, Bosshard, H.R. 登録日 2004-07-20 公開日 2004-10-05 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Inverse electrostatic effect: electrostatic repulsion in the unfolded state stabilizes a leucine zipper. Biochemistry, 43, 2004
5VYC	Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A. 登録日 2017-05-24 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Rep, 20, 2017
5VOS	VGSNKGAIIGL from Amyloid Beta determined by MicroED 分子名称: Amyloid beta A4 protein 著者 Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S, Griner, S.L, Gonen, T. 登録日 2017-05-03 公開日 2018-01-03 最終更新日 2024-03-13 実験手法 ELECTRON CRYSTALLOGRAPHY (1.42 Å) 主引用文献 Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J. Biol. Chem., 293, 2018
5UTM	Mutant Structures of Streptococcus Agalactiae GBS Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Schormann, N, Ulett, G.C, Chattopadhyay, D. 登録日 2017-02-15 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Mutant Structures of Streptococcus agalactiae GAPDH To Be Published
5WEC	Structure of an alternative pilotin from the type II secretion system of Vibrio cholerae 分子名称: Lipoprotein 著者 Williamson, Z.A, Reed, R.W, Korotkov, K.V. 登録日 2017-07-08 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.563 Å) 主引用文献 Structure and function of a new pilotin from the type II secretion system of Vibrio cholerae To Be Published
5TER	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-chloro-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-8-methyl-2-naphthonitrile (JLJ651), a Non-nucleoside Inhibitor 分子名称: 5-chloro-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-8-methyl-2-naphthonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... 著者 Chan, A.H, Anderson, K.S. 登録日 2016-09-22 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents. ACS Med Chem Lett, 7, 2016
3PGT	CRYSTAL STRUCTURE OF HGSTP1-1[I104] COMPLEXED WITH THE GSH CONJUGATE OF (+)-ANTI-BPDE 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7,8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID, PROTEIN (GLUTATHIONE S-TRANSFERASE), ... 著者 Ji, X, Xiao, B. 登録日 1999-03-22 公開日 1999-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1. Biochemistry, 38, 1999
3TTI	Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol 著者 Plantevin-Krenitsky, V, Nadolny, L, Delgado, M, Ayala, L, Clareen, S, Hilgraf, R, Albers, R, Hegde, S, D'Sidocky, N, Sapienza, J, Wright, J, McCarrick, M, Bahmanyar, S, Chamberlain, P, Delker, S.L, Muir, J, Giegel, D, Xu, L, Celeridad, M, Lachowitzer, J, Bennett, B, Moghaddam, M, Khatsenko, O, Katz, J, Fan, R, Bai, A, Tang, Y, Shirley, M.A, Benish, B, Bodine, T, Blease, K, Raymon, H, Cathers, B.E, Satoh, Y. 登録日 2011-09-14 公開日 2012-02-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
3U85	Crystal structure of human menin in complex with MLL1 分子名称: Histone-lysine N-methyltransferase 2A, Menin 著者 Huang, J, Wan, B, Lei, M. 登録日 2011-10-15 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
4ZK0	Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure 分子名称: Serpin B4, ZINC ION 著者 Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J. 登録日 2015-04-29 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates. Biochem Biophys Rep, 2, 2015
4ZK3	Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. Low pH structure 分子名称: Serpin B3 著者 Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J. 登録日 2015-04-29 公開日 2015-07-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates. Biochem Biophys Rep, 2, 2015
5A2Q	Structure of the HCV IRES bound to the human ribosome 分子名称: 18S RRNA, HCV IRES, MAGNESIUM ION, ... 著者 Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. 登録日 2015-05-21 公開日 2015-07-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
5AJ0	Cryo electron microscopy of actively translating human polysomes (POST state). 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. 登録日 2015-02-19 公開日 2015-05-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
4YR8	Crystal structure of JNK in complex with a regulator protein 分子名称: CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 著者 Liu, X, Wang, J, Wu, J.W, Wang, Z.X. 登録日 2015-03-14 公開日 2016-03-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation. Nat Commun, 7, 2016
7PWY	Structure of human dimeric ACMSD in complex with the inhibitor TES-1025 分子名称: 2-[3-[(5-cyano-6-oxidanylidene-4-thiophen-2-yl-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]ethanoic acid, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, POTASSIUM ION, ... 著者 Cianci, M, Giacche, N, Carotti, A, Liscio, P, Amici, A, Cialabrini, L, De Franco, F, Pellicciari, R, Raffaelli, N. 登録日 2021-10-07 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis of Human Dimeric alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase Inhibition With TES-1025. Front Mol Biosci, 9, 2022
1P7H	Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element 分子名称: 5'-D(*AP*AP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*A)-3', 5'-D(*TP*TP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... 著者 Giffin, M.J, Stroud, J.C, Bates, D.L, von Koenig, K.D, Hardin, J, Chen, L. 登録日 2003-05-01 公開日 2003-09-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element Nat.Struct.Biol., 10, 2003
7PK5	Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein) 分子名称: Cyclic di-GMP phosphodiesterase PdeL 著者 Fadel, J, Schirmer, T. 登録日 2021-08-25 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein) To Be Published
7QVP	Human collided disome (di-ribosome) stalled on XBP1 mRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Denk, T.G, Tesina, P, Beckmann, R. 登録日 2022-01-22 公開日 2022-10-12 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Nat Commun, 13, 2022
7RBW	Structure of Biliverdin-binding Serpin of Boana punctata (polka-dot tree frog) 分子名称: BILIVERDINE IX ALPHA, Biliverdin bindin serpin 著者 Fedorov, E, Manoilov, K.Y, Verkhusha, V, Almo, S.C, Ghosh, A. 登録日 2021-07-06 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural and Functional Characterization of a Biliverdin-Binding Near-Infrared Fluorescent Protein From the Serpin Superfamily. J.Mol.Biol., 434, 2021
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. 登録日 2022-02-09 公開日 2023-02-22 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
7SC4	filamin complex-1 分子名称: Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION 著者 Liu, J, Qin, J. 登録日 2021-09-27 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage. Blood, 141, 2023

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