PDB: 71 件ウェブページステータス検索Chemie searchBIRD

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1I9C	GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM: COMPLEX WITH ADENOSYLCOBALAMIN AND SUBSTRATE 分子名称: (2S,3S)-3-methyl-aspartic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... 著者 Gruber, K, Kratky, C. 登録日 2001-03-19 公開日 2002-03-19 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Radical Shuttling in a Protein: Ribose Pseudorotation Controls Alkyl-Radical Transfer in the Coenzyme B(12) Dependent Enzyme Glutamate Mutase Angew.Chem.Int.Ed.Engl., 40, 2001
1K7Y	E. coli MetH C-terminal fragment (649-1227) 分子名称: COBALAMIN, SULFATE ION, methionine synthase 著者 Bandarian, V, Pattridge, K.A, Lennon, B.W, Huddler, D.P, Matthews, R.G, Ludwig, M.L. 登録日 2001-10-22 公開日 2001-12-21 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Domain alternation switches B(12)-dependent methionine synthase to the activation conformation. Nat.Struct.Biol., 9, 2002
8SSD	Methionine synthase, C-terminal fragment, Cobalamin and Reactivation Domains from Thermus thermophilus HB8 分子名称: Methionine synthase 著者 Yamada, K, Mendoza, J, Koutmos, M. 登録日 2023-05-08 公開日 2023-10-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo. Nat Commun, 14, 2023
8SSE	Methionine synthase, C-terminal fragment, Cobalamin and Reactivation Domains from Thermus thermophilus HB8 分子名称: COBALAMIN, Methionine synthase 著者 Yamada, K, Mendoza, J, Koutmos, M. 登録日 2023-05-08 公開日 2023-10-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo. Nat Commun, 14, 2023
8T0Q	Open state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... 著者 Tian, S, Voss, P, Pham, K, Klose, T. 登録日 2023-06-01 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase To Be Published
8T0V	Closed state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... 著者 Tian, S, Voss, P, Pham, K, Klose, T. 登録日 2023-06-01 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase To Be Published
1CB7	GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM RECONSTITUTED WITH METHYL-COBALAMIN 分子名称: CO-METHYLCOBALAMIN, D(-)-TARTARIC ACID, PROTEIN (GLUTAMATE MUTASE) 著者 Gruber, K, Reitzer, R, Kratky, C. 登録日 1999-03-03 公開日 2000-02-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights. Structure Fold.Des., 7, 1999
1CCW	STRUCTURE OF THE COENZYME B12 DEPENDENT ENZYME GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM 分子名称: CYANOCOBALAMIN, D(-)-TARTARIC ACID, PROTEIN (GLUTAMATE MUTASE) 著者 Reitzer, R, Gruber, K, Kratky, C. 登録日 1999-03-01 公開日 2000-03-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights Structure Fold.Des., 7, 1999
1BMT	HOW A PROTEIN BINDS B12: A 3.O ANGSTROM X-RAY STRUCTURE OF THE B12-BINDING DOMAINS OF METHIONINE SYNTHASE 分子名称: CO-METHYLCOBALAMIN, METHIONINE SYNTHASE 著者 Drennan, C.L, Huang, S, Drummond, J.T, Matthews, R.G, Ludwig, M.L. 登録日 1994-09-02 公開日 1995-06-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase. Science, 266, 1994
3KP1	Crystal structure of ornithine 4,5 aminomutase (Resting State) 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-ornithine aminomutase E component, ... 著者 Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. 登録日 2009-11-14 公開日 2010-01-26 最終更新日 2019-10-30 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
3KOW	Crystal Structure of ornithine 4,5 aminomutase backsoaked complex 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-ornithine aminomutase E component, ... 著者 Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. 登録日 2009-11-14 公開日 2010-01-26 最終更新日 2012-10-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
3KOX	Crystal Structure of ornithine 4,5 aminomutase in complex with 2,4-diaminobutyrate (Anaerobic) 分子名称: (2S)-2-amino-4-{[(1Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}butanoic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... 著者 Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. 登録日 2009-11-14 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
3IVA	Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half with AdoHcy bound 分子名称: COBALAMIN, Methionine synthase, NITRATE ION, ... 著者 Pattridge, K.A, Koutmos, M, Smith, J.L. 登録日 2009-08-31 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insights into the reactivation of cobalamin-dependent methionine synthase. Proc.Natl.Acad.Sci.USA, 106, 2009
3KP0	Crystal Structure of ORNITHINE 4,5 AMINOMUTASE in complex with 2,4-diaminobutyrate (DAB) (Aerobic) 分子名称: (2S)-2-amino-4-{[(1Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}butanoic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... 著者 Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. 登録日 2009-11-14 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
3IV9	Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half in a "His-On" conformation 分子名称: COBALAMIN, Methionine synthase 著者 Pattridge, K.A, Koutmos, M, Smith, J.L. 登録日 2009-08-31 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Insights into the reactivation of cobalamin-dependent methionine synthase. Proc.Natl.Acad.Sci.USA, 106, 2009
3KOY	Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic) 分子名称: (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ... 著者 Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. 登録日 2009-11-14 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
3KOZ	Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Anaerobic) 分子名称: (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ... 著者 Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. 登録日 2009-11-14 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
6REQ	METHYLMALONYL-COA MUTASE, 3-CARBOXYPROPYL-COA INHIBITOR COMPLEX 分子名称: 3-CARBOXYPROPYL-COENZYME A, COBALAMIN, GLYCEROL, ... 著者 Evans, P.R, Mancia, F. 登録日 1998-09-03 公開日 1999-09-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of substrate complexes of methylmalonyl-CoA mutase. Biochemistry, 38, 1999
3REQ	METHYLMALONYL-COA MUTASE, SUBSTRATE-FREE STATE (POOR QUALITY STRUCTURE) 分子名称: ADENOSINE, COBALAMIN, METHYLMALONYL-COA MUTASE 著者 Evans, P.R, Mancia, F. 登録日 1997-12-04 公開日 1998-03-18 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism. Structure, 6, 1998
7REQ	METHYLMALONYL-COA MUTASE, 2-CARBOXYPROPYL-COA INHIBITOR COMPLEX 分子名称: 2-CARBOXYPROPYL-COENZYME A, COBALAMIN, GLYCEROL, ... 著者 Evans, P.R, Mancia, F. 登録日 1998-09-10 公開日 1998-09-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of substrate complexes of methylmalonyl-CoA mutase. Biochemistry, 38, 1999
1REQ	METHYLMALONYL-COA MUTASE 分子名称: COBALAMIN, DESULFO-COENZYME A, GLYCEROL, ... 著者 Evans, P.R, Mancia, F. 登録日 1996-01-19 公開日 1997-01-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution. Structure, 4, 1996
8STA	Isobutyryl-CoA mutase fused in the presence of GMPPCP 分子名称: Isobutyryl-CoA mutase fused 著者 Vaccaro, F.A, Drennan, C.L. 登録日 2023-05-09 公開日 2023-08-09 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase. J.Biol.Chem., 299, 2023
5REQ	Methylmalonyl-COA MUTASE, Y89F Mutant, substrate complex 分子名称: COBALAMIN, GLYCEROL, METHYLMALONYL(CARBADETHIA)-COENZYME A, ... 著者 Evans, P.R, Thomae, N.H. 登録日 1998-08-03 公開日 1998-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase. Biochemistry, 37, 1998
6OXD	Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Itaconyl coenzyme A, ... 著者 Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M. 登録日 2019-05-13 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Science, 366, 2019
6OXC	Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Methylmalonyl-CoA mutase large subunit, ... 著者 Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M. 登録日 2019-05-13 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Science, 366, 2019

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