PDB: 2913 件ウェブページステータス検索Chemie searchBIRD

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6PUD	Structure of human MAIT A-F7 TCR in complex with human MR1-5'OH-Pentyl-5-OP-U 分子名称: 6-[(5-hydroxypentyl)amino]-5-[(E)-propylideneamino]pyrimidine-2,4(1H,3H)-dione, Beta-2-microglobulin, Human TCR alpha chain, ... 著者 Awad, W, Rossjohn, J. 登録日 2019-07-18 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nat.Immunol., 21, 2020
2H26	human CD1b in complex with endogenous phosphatidylcholine and spacer 分子名称: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Beta-2-microglobulin, GLYCEROL, ... 著者 Garcia-Alles, L.F, Maveyraud, L, Vallina, A.T, Guillet, V, Mourey, L. 登録日 2006-05-18 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. Embo J., 25, 2006
1DQQ	CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY HYHEL-63 分子名称: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN) 著者 Li, H, Mariuzza, R.A. 登録日 2000-01-04 公開日 2000-01-19 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,). Biochemistry, 39, 2000
3O3A	Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2010-07-23 公開日 2010-12-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition. J.Med.Chem., 53, 2010
2WY3	Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands 分子名称: 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Mueller, S, Zocher, G, Steinle, A, Stehle, T. 登録日 2009-11-11 公開日 2010-02-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the Hcmv Ul16-Micb Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse Nkg2D Ligands. Plos Pathog., 6, 2010
6PUG	Structure of human MAIT A-F7 TCR in complex with human MR1-2`OH-Ethyl-5-OP-U 分子名称: 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione, Beta-2-microglobulin, CHLORIDE ION, ... 著者 Awad, W, Rossjohn, J. 登録日 2019-07-18 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nat.Immunol., 21, 2020
5EFI	Crystal structure of mouse CD1d in complex with the p99p lipopeptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Girardi, E, Wang, J, Zajonc, D.M. 登録日 2015-10-23 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of an alpha-Helical Peptide and Lipopeptide Bound to the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule CD1d. J.Biol.Chem., 291, 2016
1FZO	MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A. 登録日 2000-10-03 公開日 2001-03-28 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity. Immunity, 14, 2001
2AXF	The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation 分子名称: 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ... 著者 Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R. 登録日 2005-09-05 公開日 2005-11-29 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation J.Exp.Med., 202, 2005
3BP7	The high resolution crystal structure of HLA-B*2709 in complex with a Cathepsin A signal sequence peptide, pCatA 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A. 登録日 2007-12-18 公開日 2008-12-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens J.Biol.Chem., 284, 2009
1JGU	STRUCTURAL BASIS FOR DISFAVORED ELIMINATION REACTION IN CATALYTIC ANTIBODY 1D4 分子名称: (2-AMINO-3-PHENYL-BICYCLO[2.2.1]HEPT-2-YL)-PHENYL-METHANONE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Larsen, N.A, Heine, A, Crane, L, Cravatt, B.F, Lerner, R.A, Wilson, I.A. 登録日 2001-06-26 公開日 2001-12-05 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. J.Mol.Biol., 314, 2001
3BO8	The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. 登録日 2007-12-17 公開日 2008-12-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity Protein Sci., 18, 2009
8SBK	Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A). 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, ... 著者 Mallik, L, Young, M.C, Sgourakis, N.G. 登録日 2023-04-03 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
3C5J	Crystal structure of HLA DR52c 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Elongation factor 1-alpha 2, HLA class II histocompatibility antigen, ... 著者 Dai, S, Kappler, J.W. 登録日 2008-01-31 公開日 2008-08-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proc.Natl.Acad.Sci.USA, 105, 2008
3X13	Crystal structure of HLA-B*0801.N80I 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... 著者 Vivian, J.P, Rossjohn, J. 登録日 2014-10-24 公開日 2014-12-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope J.Immunol., 194, 2015
5W38	1.80A resolution structure of human IgG3 Fc (N392K) 分子名称: CITRATE ANION, Immunoglobulin heavy constant gamma 3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Lovell, S, Mehzabeen, N, Battaile, K.P, Shah, I, Tolbert, T.J. 登録日 2017-06-07 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural characterization of the Man5 glycoform of human IgG3 Fc. Mol. Immunol., 92, 2017
3FQT	Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes 分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ... 著者 Petersen, J, Rossjohn, J. 登録日 2009-01-07 公開日 2009-03-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes Proc.Natl.Acad.Sci.Usa, 106, 2009
1KCV	Crystal structure of antibody pc282 分子名称: PC282 IMMUNOGLOBULIN 著者 Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. 登録日 2001-11-11 公開日 2002-05-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response. J.Immunol., 168, 2002
1UM6	catalytic antibody 21h3 分子名称: antibody 21h3, H chain, L chain 著者 Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. 登録日 2003-09-23 公開日 2004-10-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms To be Published
1UVQ	Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, GLYCINE, ... 著者 Siebold, C, Hansen, B.E, Wyer, J.R, Harlos, K, Esnouf, R.E, Svejgaard, A, Bell, J.I, Strominger, J.L, Jones, E.Y, Fugger, L. 登録日 2004-01-22 公開日 2004-02-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy Proc.Natl.Acad.Sci.USA, 101, 2004
5VUE	HLA-B*57:01 presenting LTVQVARVW 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-19 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
2ZSV	Crystal structure of H-2Kb in complex with JHMV epitope S598 分子名称: 8-mer peptide from spike glycoprotein, Beta-2-microglobulin, CYSTEINE, ... 著者 Theodossis, A, Dunstone, M.A, Rossjohn, J. 登録日 2008-09-18 公開日 2008-11-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. Plos Pathog., 4, 2008
2Z9T	Crystal structure of the human beta-2 microglobulin mutant W60G 分子名称: Beta-2-microglobulin 著者 Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M. 登録日 2007-09-26 公開日 2008-04-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties J.Mol.Biol., 378, 2008
1I7U	CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-6V 分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... 著者 Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J. 登録日 2001-03-10 公開日 2001-10-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface J.Biol.Chem., 276, 2001
3L3D	Crystal structure of HLA-B*4402 in complex with the F3A mutant of a self-peptide derived from DPA*0201 分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... 著者 Theodossis, A, Ely, L.K, Rossjohn, J. 登録日 2009-12-16 公開日 2010-03-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010

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